Notes

Advancement associated with blood-brain barrier destruction related to alterations in brain metabolites following intense ischemia.
in optimizing screening colonoscopy quality.
Increasing driving distance to screening colonoscopy was negatively associated with adequate bowel preparation but not adenoma detection. Among an academic medical center population, the likelihood of adequate bowel preparation was highest in patients traveling 30 miles or less to their screening colonoscopy. Patient driving distance to colonoscopy is an important consideration in optimizing screening colonoscopy quality.
Caudate hepatectomy is one of the most difficult procedures among liver surgeries because of its deep location and proximity to the inferior vena cava (IVC), particularly in patients with a history of open hepatectomies. 1,2,3 METHODS A 77-year-old man underwent three open hepatectomies for hepatocellular carcinoma (HCC), including a sub-segmentectomy of S6 and partial hepatectomies of S7 and S8 during follow-up for hepatitis C virus-associated liver cirrhosis. PBIT ic50 However, HCC recurred in the caudate lobe behind the IVC (Supplemental video file 1). We lysed the severe adhesion in the upper abdomen, including the liver hilum, and exposed the ventral surface of the caudate lobe. We then used a Nathanson retractor to ventrally retract the severely enlarged left lobe. To counteract the severe adhesion that prevented us from controlling the hepatoduodenal ligament, we used the laparoscopic Satinsky vascular clamp for hilar inflow control. Using the anterior approach, we performed parenchymal resection from the distal side of the caudate lobe. Then, we gradually exposed the ventral surface of the IVC and separated the caudate lobe from the IVC. The IVC ligament was divided, and the caudate lobe, including the tumor behind the IVC, was removed.

The operation time was 229 min with a total hepatic hilar clamping time of 69 min and blood loss of 10 mL. The patient was discharged on postoperative day 8 without any complications. Pathological examination revealed moderately differentiated HCC (pT1N0M0) with a negative surgical margin.

The laparoscopic approach using specialized laparoscopic instruments is feasible for a tumor located in the caudate lobe behind the IVC, even in patients with a history of multiple open hepatectomies.
The laparoscopic approach using specialized laparoscopic instruments is feasible for a tumor located in the caudate lobe behind the IVC, even in patients with a history of multiple open hepatectomies.Many past cannabis prevention campaigns have proven largely ineffective due in part to the diversity of adolescents' cannabis-relevant beliefs. The current studies evaluated the impact of a sequential multiple message approach tailored to the usage norms of adolescents expressing negative attitudes toward a cannabis prevention appeal. A multiple-message strategy was implemented-initial unfavorable message evaluations were invalidated using attitudinal rebuttal feedback prior to presenting a third tailored communication. Participants were cannabis-abstinent middle and high school students (ages 11 to 16). Study 1 (N = 808) compared effects of gain- and loss-framed messages tailored to each student's normative usage perceptions. In Study 2 (N = 391), students were randomly assigned to receive a tailored or non-tailored message after receiving feedback meant to destabilize anti-message attitudes. For at-risk adolescents in Study 1 who perceived cannabis use as normative, a tailored gain-framed message resulted in the lowest usage intentions (p less then .05). In Study 2, a conditional multiple-moderated mediation model showed that for high-risk teens with normative beliefs and pro-cannabis attitudes, exposure to a tailored gain-framed communication was associated with decreased cannabis attitude certainty, and lower usage intentions 2 months later (p less then .05). Findings have implications for sequential messaging utilization in mass media campaigns and support the efficacy of tailored messages over a one-size-fits-all media approach. Further, results suggest that systematically weakening resistance to persuasive communications and tailoring messages consistent with individually perceived peer norms is an effective prevention strategy.
Splenic abscess is a rare complication following sleeve gastrectomy.

We performed a systematic review to clarify its clinical significance, presentation, and management. PubMed, Embase, MEDLINE, Google Scholar, and the Cochrane Library were searched up to the 19th of July 2020. A total of 18 patients were included, of which 11 were female and 7 were male. The mean age was 34.1 ± 12.3 years, and the mean body mass index was 45.8 ± 7.6 kg/m
. Type 2 diabetes mellitus was reported in 11.1% of patients and hypertension in 22.2%. Fever was the most common presenting symptom seen in 17 (94.4%) patients, followed by abdominal pain in 10 (55.6%). The mean duration from surgery to presentation was 98.6 ± 132.7 days (range 10-547 days). Computed tomography was used for investigations in 17/18 (94.4%) patients. Seven patients had reported leak, three reported bleeding, and 2 reported pleural effusion. Thirteen patients had unilocular abscess. All patients were treated with antibiotics. Four patients needed total parenteral nutrition, and three were given proton pump inhibitor. In total, 11 patients needed percutaneous drainage as a part of treatment and 11 patients needed total splenectomy and 1 needed partial splenectomy.

Splenic abscess following sleeve gastrectomy is a rare identity. The etiology of formation of splenic abscess needs further studies. A computed tomography of the abdomen with contrast is the preferred diagnostic tool. There is no gold standard treatment for splenic abscess.
Splenic abscess following sleeve gastrectomy is a rare identity. The etiology of formation of splenic abscess needs further studies. A computed tomography of the abdomen with contrast is the preferred diagnostic tool. There is no gold standard treatment for splenic abscess.
Single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is a bariatric procedure based on the standard duodenal switch surgery. It was first introduced in 2007 as a procedure for individuals with clinically severe obesity. Till date, primary SADI-S has not been used on Chinese with diabetes and body mass index (BMI) < 35 kg/m
.

Here, we account the use of this novel surgery in Chinese with diabetes and BMI < 35 kg/m
.

All relevant medical information, involving patients with diabetes and BMI < 35 kg/m
, who received primary SADI-S at Beijing Shijitan Hospital from June 2017 to December 2018, was retrospectively assessed.

Twenty-six patients were selected for evaluation, and all of them completed a 2-year follow-up. The age, diabetic duration, and preoperative BMI were 35.5 (range 20-63) years, 3.5 (range 0.5-18) years, and 34.40 (range 28.74-34.96) kg/m
, respectively. At 24 months, the percentage of total body weight loss (%TWL) and BMI were 26.26 (range 13.33-43.88) and 24.
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