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001). Multivariate analysis revealed that education, title, working hours per week, frequency of night shift were risk factors for psychological symptoms.
The situation of psychological health of ICU physicians in China is worrying, and it is urgent to take some effective measures to improve their mental health.
The situation of psychological health of ICU physicians in China is worrying, and it is urgent to take some effective measures to improve their mental health.Radiocesium was dispersed from the Fukushima Dai-ichi disaster in March 2011, causing comparatively high radioactive contamination in nearby environments. Radionuclide concentrations in wild rodents (Apodemus argenteus, and Apodemus speciosus) within these areas were monitored from 2012 to 2016. However, whole-organism to soil transfer parameters (i.e., concentration ratio, CRwo-soil) for wild rodents at Fukushima were not determined and hence were lacking from the international transfer databases. We augmented the 2012-2016 data by collecting soil activity concentrations (Bq kg-1, dry mass) from five rodent sampling sites in Fukushima Prefecture, and developed corresponding CRwo-soil values for radiocesium (134Cs and 137Cs) based on rodent radioactivity concentrations (Bq kg-1, fresh mass). The CRwo-soil were added to the Wildlife Transfer Database (WTD; http//www.wildlifetransferdatabase.org/), supporting the development of the International Commission on Radiological Protection's (ICRP) environmental protection framework, and increasing the WTD from 84 to 477 entries for cesium and Muridae ('Reference Rat'). Significant variation occurred in CRwo-soil values between study sites within Fukushima Prefecture. The geometric mean CRwo-soil, in this paper, was higher than that reported for Muridae species for Chernobyl. Radiocaesium absorbed dose rates were also estimated for wild rodents inhabiting the five Fukushima study sites and ranged from 1.3 to 33 μGy h-1. Absorbed dose rates decreased by a factor of two from 2012 to 2016. Dose rates in highly contaminated areas were within the ICRP derived consideration reference level for Reference Rat (0.1-1 mGy d-1), suggesting the possible occurrence of deleterious effects and need for radiological effect studies in the Fukushima area.
Proprioception is the awareness of body parts and includes joint position sense, kinesthesia, and sense of force. Cervical spine is one of the major affected areas in axial spondyloarthritis (axSpA), and is an essential region for proprioceptive receptors.
To investigate the cervical joint proprioceptive accuracy by using cervical joint positioning error (JPE) method in patients with axSpA and healthy controls.
Cross-sectional study.
JPE was calculated for cervical motions in the directions of flexion, extension, rotations, and lateral flexions. Time since diagnosis, symptom duration, spinal mobility, functional status, quality of life, disease activity, and pain were evaluated in axSpA patients. Cervical JPE of axSpA patients was also compared according to radiographic status, biologic use, and existence of cervical syndesmophytes.
Eighty-two axSpA patients (52 males) and 71 healthy subjects (53 males) were evaluated. Cervical JPE was higher in patients with axSpA compared to healthy subjects (p<0.001), except left lateral flexion (p=0.10). Cervical proprioceptive accuracy for extension and left rotation was better in biologics+subgroup compared to biologic- subgroup (p<0.05). No other differences were detected related to radiographic status nor existence of cervical syndesmophytes (p>0.05).
Cervical proprioception accuracy is impaired in patients with axSpA. It seems that controlling disease activity by using appropriate medication may have a positive effect on cervical proprioception accuracy.
Cervical proprioception accuracy is impaired in patients with axSpA. It seems that controlling disease activity by using appropriate medication may have a positive effect on cervical proprioception accuracy.Ultra-fast magic-angle spinning (UFMAS) at a MAS rate (ωR/2π) of 60 kHz or higher has dramatically improved the resolution and sensitivity of solid-state NMR (SSNMR). However, limited polarization transfer efficiency using cross-polarization (CP) between 1H and rare spins such as 13C still restricts the sensitivity and multi-dimensional applications of SSNMR using UFMAS. Selleckchem BTK inhibitor We propose a novel approach, which we call decoherence-optimized tilted-angle CP (DOTA CP), to improve CP efficiency with prolonged lifetime of 1H coherence in the spin-locked condition and efficient band-selective polarization transfer by incorporating off-resonance irradiation to 1H spins. 13C CP-MAS at ωR/2π of 70-90 kHz suggested that DOTA CP notably outperformed traditional adiabatic CP, a de-facto-standard CP scheme over the past decade, in sensitivity for the aliphatic-region spectra of 13C-labeled GB1 protein and N-formyl-Met-Leu-Phe samples by up to 1.4- and 1.2-fold, respectively. 1H-detected 2D 1H/13C SSNMR for the GB1 sample indicated the effectiveness of this approach in various multidimensional applications.Developing low-cost and efficient methods to enhance the electrochemiluminescence (ECL) intensity of luminophores is highly desirable and challenging. Herein, we develop a synergistic promotion strategy based on three types of co-reaction accelerators to achieve an efficient SnO2 quantum dots (SnO2 QDs)-based ternary ECL system. Specifically, the MnO2 nanoflowers (MnO2 NFs), Ag nanoparticles (Ag NPs) and hemin/G-quadruplex were rationally selected as co-reaction accelerators. Owing to the synergistic effect, the deft integration of three types of co-reaction accelerators enabled better structural stability, more exposed catalytic active sites, and faster charge transfer, thus more effectively facilitating the reduction of co-reactant (S2O82-) compared with that of the single co-reaction accelerator. To demonstrate the practical utility of this principle, an "on-off-super on" ECL biosensor was constructed in combination with a 3D DNA walker, which showed a superior linear range (10 aM-100 pM) and a low detection limit (2.
My Website: https://www.selleckchem.com/btk.html
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