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05). Significant differences between patients with and without OSA were found on the PANSS negative symptoms subscale, B-CATS digit symbol test, and in daytime sleepiness. None of the used screening scales showed satisfactory sensitivity and specificity. Obesity with coexisting neck circumference ≥41 cm in women or ≥43 cm in men (BMI-NECK model) predicted OSA in 57% of cases. CONCLUSIONS OSA should be screened in patients with schizophrenia as it has a negative influence on psychiatric symptoms and may contribute to the higher mortality of these patients. Assessment of BMI and neck circumference proves a good screening test in ambulatory contexts. Anti-NMDAR encephalitis most commonly presents to psychiatric services, so early identification of this disorder is essential. We aim to validate the two screening criteria (Scott et al. and Herken and Pruss) which have been proposed to identify first episode psychosis patients who should have anti-NMDAR antibody testing. The performance of the screening criteria were assessed using anti-NMDAR encephalitis cases published in the literature, and antibody positive and negative cases from a state-wide cohort (Queensland, Australia). Sensitivity, specificity and area under receiver operator characteristic curve analysis was performed. There were 258 anti-NMDAR encephalitis cases and 103 control cases, which demonstrated high performance of both Scott et al. "screening recommended" criteria (sensitivity 97.3%, specificity 85.4%, AUC 0.914) and Herken and Pruss "yellow flags" criteria (sensitivity 91.5%, specificity 83.5%, AUC 0.875). These criteria remained accurate when neurological variables were excluded, and in cases without psychosis. The Scott et al. "screening not recommended", and Herken and Pruss "red flags" criteria did not demonstrate clinical utility for first episode psychosis case screening. The screening criteria with good performance identify an atypical picture of psychiatric presentation with increased risk of anti-NMDAR positivity prior to overt neurological symptoms or investigations and may be beneficial to include in the routine psychiatric assessment process. Visual nonlinguistic local and global priming can change one's state of mind and influence other upcoming tasks. Reading involves both detailed and higher-level global processing. Little is known about the effects of visual non-linguistic priming on lower level processing of words, as well as about the potentially higher-level processing of written information. In two experiments, the effects of global versus local priming on single word reading (Experiment 1) as well as text reading (Experiment 2) were investigated in adults. The results revealed facilitation effects of local priming on single word reading as well as on text reading rate, with no impairment of reading accuracy and comprehension. These novel results are further interpreted within different cognitive and neurological frameworks. In addition, clinical and research implications for the local/global attention and reading domain are discussed. Boredom is an everyday experience during uneventful situations and while waiting. Such situations are typically described as unpleasant since oneself becomes the focus of awareness, and the subjective duration expands. Self-control is an individual trait that helps to cope with unpleasant situations. Hardly any systematic studies exist on real waiting situations where people's boredom and subjective time experience are assessed in relation to self-control. Therefore, we assessed 99 participants who first filled out self-report questionnaires on emotional and metacognitive control, the Scale for Experiencing Emotions (SEE) and the Temporal Metacognition Scale (TMCS). After giving a fake reason for why they had to wait, participants were shut in an empty room alone for 7.5 minutes and afterwards asked to report their impressions regarding the experienced time and reactions to the situation. SBE-β-CD datasheet Boredom was associated with the feeling of time passing more slowly and more frequent thoughts about time. The propensity to self-regulate was related to less awareness of time and to lower levels of boredom. Mediation analyses revealed that the level of boredom mediates the relationships between self-regulation processes and time perception. The results provide new insights into the association between time perception and boredom as states in a real situation and self-regulation as a trait. Effects of temperature on metabolism/biotransformation and toxicokinetics to lizards are significant, but frequently ignored in toxicology studies. Beta-cyfluthrin (BC) is a pyrethroid insecticide and has been widely used globally. The study aimed to understand the diverse adverse effects of BC to the lizard (Eremias argus) at different temperature regimes. We carried out a single oral BC treatment (20 mg/kg bw) for toxicokinetic study and a 7-day BC (10 mg/kg bw) gavage to look at toxicology by monitoring changes in the biomarkers HSP70, SOD, MDA, CarE, UDPGT, GST, cyp genes, and other metabolic responses. Results showed that BC was lethal to lizards, showing oxidative damages in the liver at ambient temperature (25 °C). Heat stress (35 °C) could exacerbate the oxidative damage (MDA increased) caused by BC, due to the disorder of the antioxidant defense system. The result of tissue distribution and toxicokinetic study also showed that temperature affected the BC biotransformation in lizards. The biotransformation of BC maybe relates to the activation of CarE and UDGPT by heat stress. However, the cyp system and GST didn't increase under BC or/and heat treatments. 1H-NMR metabolomics analysis showed that BC or/and heat stress interfered with energy and amino acid metabolism of the liver. Unlike acute lethal toxicity, the occurrence of the BC and heat stresses has detrimental effects on lizard individuals and populations on sub-lethal levels. Our results indicate that pollution and global warming (or some other extremely weather) may generate significant and harmful effects on lizards. Heat stress has been recognized as one of the consequences of climate change in urban areas. Its adverse effects on the urban population range from economy, social, environment, and human health. With the increasing urbanization and economic development in cities, heat stress is expected to worsen. This particular study aims to achieve two objectives (1) to understand the determinants of heat stress, especially the roles of the urban environment in exacerbating the heat stress, and (2) to explore the effects of heat stress to human health using self-reported health assessment. We employed a cross-sectional study using a survey questionnaire from 505 respondents living in the urban area of Bangkok, Thailand. We found that socioeconomic conditions of the individual and urban environment were significant determinants of urban heat stress. Low-income urban populations living in high-density areas with less green open space were more likely to experience heat stress. We also found that heat stress significantly affects human health.
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