Notes

JC polyomavirus mutants avoid antibody-mediated neutralization.
Communication skills are a core competence in veterinary medicine. These skills play a pivotal role in professional success in the animal health professions. Over the last few decades, there has been an increased focus on communication skills in veterinary curricula. Conversely, we know less about the knowledge and motivation behind the communication skills of those veterinarians in different work domains who are acting as mentors outside the university. In 2016, semi-structured interviews (n = 16) were conducted with German practitioners in workplaces ranging from companion to farm animal practice, and throughout the veterinary industry, veterinary research and government service. We combined two qualitative methods a thematic analysis approach and the generation of types to identify characteristics associated with the acquisition of communication skills. In the current study, three main themes were developed "Motivation," "Experiences with the acquisition of communication skills," and "Communication skills training during formal education." Within the identified themes, we recognized three types of communicators "self-experienced," "extrinsic-experienced," and "unexperienced." We found that acquisition of communication skills was closely linked to motivation; therefore, motivation must be considered when developing communication skills curricula for learners and educators. By extrapolating the findings of this explorative study, we determined that intrinsically motivated mentors from the field should be a main source of veterinary education to promote further development in communication training. This qualitative study also determined that most nonuniversity veterinary mentors had only a basic knowledge of teaching and learning communication skills, leading us to recommend formal training. Interchange between practicing veterinarians and veterinary educators and curriculum coordinators can foster relevant curricular modifications.An innovative training program entitled "AgSecure Africa ProgrammeTM" was developed in partnership with the South African Agricultural Research Council-Onderstepoort Veterinary Research (ARC-OVR) to train veterinarians, animal health technicians, researchers and laboratory personnel. Three blended courses consisting of both virtual and in person delivery were provided with the intent of contributing to the better prevention, detection and control of infectious diseases of livestock and poultry of significant importance for the region with a strong emphasis on transboundary animal diseases. A "train the trainer" model of instruction was employed to equip participants with the ability to train and share knowledge with colleagues and small-holder farmers in their various communities and regions. The design of this program was to increase the capacity of veterinarians and veterinary diagnosticians to safely and accurately diagnose infectious livestock diseases and to also empower small-holder farmers with the knowledge needed to safely and securely manage their livestock and be a first line defense in the prevention and control of infectious livestock diseases. Quantitative and qualitative evaluations were used to measure the impact of the trainings which revealed significant increases in knowledge gains. Course materials were submitted and approved for accreditation by the South African Veterinary Council (SAVC) becoming the first international training program to achieve this. Approval of these courses led to licensed veterinarians and animal health technicians being awarded continuing professional development credits upon their successful completion of courses. A larger goal was to build training capacity, not only for South Africa, but also for the region.Communication skills are teachable and learnable skills, which have a vital position among other clinical skills because a student's ability to communicate can increase empathy. Empathy scores tend to be higher for women than for men. The focus of this article is to determine how senior students evaluate themselves regarding communication competence and whether gender has an impact on their perception. The study included 128 volunteering students, using the Communication Competence Scale, consisting of 30 questions, as a data collection tool and the independent samples t-test for statistical evaluations. The evaluation of all participants showed that male participants had the highest score, and female participants had the lowest. However, there was no statistically significant difference between female and male participants' total scores (p = 0.605). There was a statistically significant difference between female and male students in terms of the social competency, empathy, and adaptability. find more Female scores for empathy were statistically higher than those of males. Male students scored themselves higher than females in terms of social competency and adaptability. In the context of the students' perceptions of their communication competence, it was determined that women assessed themselves to be more empathetic and men perceived themselves to be more social and adaptable. This research is significant as it is the first study of Turkish veterinary students' self-perception of communication competence. Communication training may become more robust in veterinary curricula in Turkey, and further research will be affected by this issue.Fibroblast activation includes differentiation to myofibroblasts and is a key feature of organ fibrosis. The Notch pathway has been involved in myofibroblast differentiation in several tissues, including the lung. Here, we identify a subset of collagen-expressing cells in the lung that exhibit Notch3 activity at homeostasis. After injury, this activation increases, being found in αSMA-expressing myofibroblasts in the mouse and human fibrotic lung. Although previous studies suggest a contribution of Notch3 in stromal activation, in vivo evidence of the role of Notch3 in lung fibrosis remains unknown. In this study, we examine the effects of Notch3 deletion in pulmonary fibrosis and demonstrate that Notch3-deficient lungs are protected from lung injury with significantly reduced collagen deposition after bleomycin administration. The induction of profibrotic genes is reduced in bleomycin-treated Notch3-knockout lungs that consistently present fewer αSMA-positive myofibroblasts. As a result, the volume of healthy lung tissue is higher and lung function is improved in the absence of Notch3.
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