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-diabetic children was not statistically significant. The CRT analysis revealed a higher frequency of "critical" pH values (pH = 4.5-5.5) and higher Lactobacillus counts in diabetic children than in non-diabetic children, which indicated a higher caries risk in the former group.
Arch wire surface characteristics, especially surface roughness and topography, influence the coefficient of friction during sliding. The clinician should be familiar with the properties of orthodontic appliances and materials that could result in high friction to maximize the efficiency of treatment. This study aimed to compare the static friction of orthodontic arch wire materials, including a newly introduced low-friction TMA, conventional TMA, and stainless steel arch wires, using an Instron universal testing machine and to evaluate their surface topographical features using a noncontact optical profilometer
A total of 30 arch wire specimens were used, including 10 low-friction TMA (TMA-Low), 10 conventional TMA (TMA-C), and 10 stainless steel (SS), (Ormco, Orange, CA, USA) measuring 0.016×0.022in. The static frictional force of each arch wire material was measured using the universal Instron machine. The surface topography was evaluated using a noncontact profilometer machine.
The static frictional resistance forces were highest in the TMA-C alloy group, and the value was statistically significant in comparison to the SS arch wire but not to the TMA-Low arch wire. The mean value of the static friction of the TMA-Low group was intermediate between the TMA-C and SS arch wires. However, this difference was statistically insignificant compared to the other two alloys. A surface roughness evaluation using a profilometer machine revealed that the highest mean of all three roughness parameters was found in the TMA-C group, followed by the TMA-Low and SS arch wires in descending order.
The static friction resistance forces and surface roughness values of the TMA-Low arch wire are comparable to those of TMA-C but are still considered inferior to those of the SS arch wire.
The static friction resistance forces and surface roughness values of the TMA-Low arch wire are comparable to those of TMA-C but are still considered inferior to those of the SS arch wire.
Matrix metalloproteinases (MMPs) are proteolytic enzymes involved in extracellular matrix remodeling of all body tissues, including oral tissues such as gingival tissue. Expression levels of MMPs are widely studied as important biomarkers for explaining the biochemical mechanisms and evolution of many oral diseases.
Demonstrate the sensitivity, reproducibility, repeatability, and robustness of the dot blot assay for the relative quantification of MMP-8 and MMP-9 expression levels in patients with GO associated with orthodontic treatment.
A validated dot blot assay was used to compare the relative expression levels of MMP-8 and MMP-9 in gingival samples. Methodological variability, reproducibility, sensitivity and robustness were determined with the use of control samples from healthy donors (G1). Next, expression levels were measured in gingival tissue from patients with mild and moderate gingival overgrowth associated with orthodontic treatment (G3 and G4) and patients without gingival overgrowth but with a history of using orthodontic appliances (G2).
Dot blot assay demonstrated that MMP-8 and MMP-9 expression levels were higher in patients with gingival overgrowth and distinguished those with moderate clinical grade (G4) from those with mild overgrowth (G3). In addition, patients with a history of orthodontic treatment showed similar expression levels to the control group two years after removing orthodontic appliances.
With the assay used, we were able to detect differences in MMP-8 and MMP-9 expression in patients with different levels of severity of gingival overgrowth. Dot blot could be used to measure MMPs during the onset and progression of gingival overgrowth.
With the assay used, we were able to detect differences in MMP-8 and MMP-9 expression in patients with different levels of severity of gingival overgrowth. Dot blot could be used to measure MMPs during the onset and progression of gingival overgrowth.
The objective was to compare water flosser and regular floss in the efficacy of plaque removal in patients after single use.
A randomized controlled clinical trial was conducted to compare the plaque removal efficacy of water flosser and regular floss. learn more Eighty three subjects who met the inclusion criteria were recruited from dental clinic. Silness and Löe plaque index was measured for all the subjects prior to and after the intervention by an examiner who was blind to the type of aid used. The type of floss used was randomly assigned to each side of the oral cavity; unflavored waxed regular floss (oral B) used on one side, while a water flosser (Waterpik® Cordless Plus Water Flosser) was used on the other side. A trained investigator used either unflavored waxed regular floss or water flosser as assigned. Paired
-test was used to compare between the two groups.
The mean plaque scores at baseline were 1.10(±0.38) and 0.94(±0.38) respectively for regular floss and water flosser. The mean plaque scores wejects with fixed prostheses or undergoing orthodontic treatment.
The morbidities and complications reported in the reconstruction of large bony defects have inspired progression in the field of bioengineering, with a recent breakthrough for the use of decellularized skeletal muscle grafts (DSMG).
To assess the osteogenic potentials of seeded DSMG
and to investigate bone regeneration in critical size defect
Assessment of cell viability and characterization was carried out on seeded DSMG for different intervals
. For
experiments, histological analysis was performed for rat cranial defects for the following groups (A) non-treated DSMG and (B) seeded DSMG after a period of 8weeks.
The
experiment demonstrated the lack of cytotoxicity and inert properties of seeded DSMG; these facilitated the osteogenic differentiation and significant gene expressions, particularly of
,
, and
(1.9174±0.11673, 1.1806±0.02383, and 1.1802±0.00775, respectively). In the
experiment, superior results were detected in the seeded DSMG group which showed highly vascularized and cellular dense connective tissue with deposited bone matrix and multiple scattered islets of newly formed bone.
Website: https://www.selleckchem.com/products/h-cys-trt-oh.html
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