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Transport involving PFOS throughout aquifer deposit: Carry actions as well as a distributed-sorption product.
Multipole electromagnetic resonances and their couplings are of crucial importance for both the fundamental understanding of light scattering by high-index all-dielectric nanostructures and lots of nanophotonic applications based on those nanostructures. Here, we show that magnetic dipole modes in a dielectric nanodisk cluster can easily form a magnetic toroidal dipole (MTD) mode. The cluster consists of five silicon nanodisks, where each nanodisk holds a magnetic dipole mode. These magnetic dipole modes can collectively couple with each other and form a MTD mode under suitable excitation. The MTD mode is confirmed by multipole expansion calculations and near field distributions, where two closed loops of magnetic field with opposite directions are seen. The response of the MTD is strong and comparable to that of a common electric dipole or magnetic dipole mode. It is also found that the MTD resonance is accompanied by an electric toroidal quadrupole mode in the cluster. The MTD mode is tunable by varying the geometries. We also fabricated silicon nanoparticle clusters and verified the MTD mode in the experiment. Our results illustrate the controllable excitation of strong high-order electromagnetic modes and these modes may open new opportunities for light manipulation at the nanoscale.The development of intelligent and precise cancer therapy systems that enable accurate diagnosis and specific elimination of cancer cells while protecting normal cells to improve the safety and effectiveness of the treatment is still a challenge. Herein, we report a novel activatable nanodevice for precise cancer therapy. The nanodevice is constructed by adsorbing a DNA duplex probe onto MnO2 nanosheets. After cellular uptake, the DNA duplex probe undergoes telomerase-triggered conformation switching, resulting in a Ce6 "turn-on" signal for the identification of cancer cells. Furthermore, Deoxyribozyme (DNAzyme) is activated to catalyse the cleavage of survivin mRNA, actualizing a precise synergistic therapy in cancer cells involving photodynamic therapy and gene-silencing. The MnO2 nanosheets provide Mn2+ for the DNAzyme and relieve hypoxia to improve the efficiency of the photodynamic therapy. Live cell studies reveal that this nanodevice can diagnose cancer cells and specifically eliminate them without harming normal cells, so making the treatment safer and more effective. The developed DNA-MnO2 nanodevice provides a valuable and general platform for precise cancer therapy.3D spongy nanofiber structure Fe-NC catalysts were constructed by a graphene regulated electrospinning method. The framework of the catalysts was reconstructed into carbon nanotubes, mesopores and macropores, and most of the Fe3C is converted to Fe2N during the calcination process. All catalysts showed better electrocatalytic performances than commercial Pt/C.Two aza-BODIPY photosensitizers (PSs, compounds 7 and 8), featuring an iodine atom on each pyrrolic unit of their structure, were synthesized in fairly good yields starting from commercial products and tested in vitro on two human cancer cell lines (HCT116 and SKOV3) to assess their photodynamic efficacy. After treating the cell cultures with variable concentrations of 7 or 8 and incubating for the desired incubation time, the cells were irradiated for two hours with a red-light emitting diode (LED) device; afterwards the extent of cell death was determined by MTT assay. Besides the killing effect, the new PSs were also studied to determine further parameters related to photodynamic efficacy, such as the resistance towards photobleaching, the rate of singlet oxygen production, the fluorescence quantum yields, the cellular uptake and the localization inside the cells and, finally, flow cytometric analysis for apoptosis. Considering the results as a whole, these aza-BODIPYs can be considered to be promising photosensitizers because of their IC50 values being below micromolar concentrations and for more rather interesting features. Actually, these molecules have proved to be (a) quite stable towards photobleaching; (b) good producers of singlet oxygen and (c) highly penetrating the cells with a wide distribution in the cytosol. Furthermore, in accordance with the good rate of singlet oxygen production, the apoptotic cells reach 30% and this allows us to assume a low inflammatory effect of the in vivo PDT treatment; thus a possible in vivo application of these aza-BODIPYs might be plausible.A new pyridine-bis(carboxamide)-based ligand with a bithiophene pendant, 2Tcbx, was synthesized. Its lanthanide ion (LnIII) complexes, [Ln(2Tcbx)2]3+, were isolated and their photophysical properties were explored. Upon excitation at 360 nm, these complexes display emission in the near-infrared (NIR) with efficiencies of 0.69% for LnIII = YbIII, 0.20% for LnIII = NdIII, and 0.01% for LnIII = ErIII, respectively. Concurrent 1O2 formation was seen for all complexes, with efficiencies of 19% for the YbIII complex, 25% for the NdIII complex, and 9% for the ErIII complex. When exciting at a longer wavelength, 435 nm, only LnIII emission was observed and larger efficiencies of LnIII-centered emission were obtained. The lack of 1O2 generation indicates that energy pathways involving different ligand conformations, which were investigated by transient absorption spectroscopy, are involved in the sensitization process, and enable the wavelength-dependent generation of 1O2.Some singly charged ionic liquids (ILs) have been reported to absorb multi-molar CO2. However, the conventional acid(CO2)-base(anion) interaction picture leads to too weak CO2 binding to support the high uptake. Later, a so-called "cation-channel" mechanism assuming the cation-to-anion proton transfer successfully explains the over equimolar CO2 uptake of some phosphonium-based ILs. Here, by employing the density functional theory (DFT) calculations, we extend the proton transfer mechanism to incorporate imidazole- and ammonium-based ILs as well. selleck chemicals For imidazole-based ILs, carbene molecules formed after the proton transfer can react strongly with CO2. More importantly, for ammonium-based ILs, the proton transfer process is feasible only with the help of CO2 molecules. Furthermore, compared to the one IL ion pair model, the model consisting of two IL ion pairs can result in stronger CO2 absorption because it can describe the intermolecular hydrogen bonds more appropriately, especially after incorporating CO2 molecules.
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