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or longer GP consultations and caution against reliance on telephone consultations in primary care; however, more research is needed to understand the underlying mechanisms.
In England, GPs are independent contractors working to a national contract. Since 2017, the contract requires GPs to use electronic tools to proactively identify moderate and severe frailty in people aged ≥65 years, and offer interventions to help those identified to stay well and maintain independent living. Little is currently known about GPs' views of this contractual requirement.
To explore GPs' views of identifying frailty and offering interventions for those living with moderate or severe frailty.
A sequential mixed-methods study of GPs in the East Midlands region of England - namely Derbyshire, Leicestershire, Lincolnshire, Nottinghamshire, and Northamptonshire - undertaken between January and May 2019.
GPs were made aware of the study via professional organisations' newsletters and bulletins, GP email lists, and social media, and were invited to complete an online questionnaire. Responses were analysed using descriptive statistics and, based on those survey responses, GPs with a range of GP animary care requires GP education, highly sensitive and specific risk-stratification tools, better access to interventions to lessen the impact of frailty, and adequate resourcing to achieve potential clinical impact.
C-reactive protein (CRP) point-of-care testing can reduce antibiotic use in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in primary care, without compromising patient care. Further safe reductions may be possible.
To investigate the associations between presenting features and antibiotic prescribing in patients with AECOPD in primary care.
Secondary analysis of a randomised controlled trial of participants presenting with AECOPD in primary care (the PACE trial).
Clinicians collected participants' demographic features, comorbid illnesses, clinical signs, and symptoms. Antibiotic prescribing decisions were made after participants were randomised to receive a point-of-care CRP measurement or usual care. Multivariable regression models were fitted to explore the association between patient and clinical features and antibiotic prescribing, and extended to further explore any interactions with CRP measurement category (CRP not measured, CRP <20 mg/l, or CRP ≥20 mg/l)nostic value of these features may help identify further safe reductions.[This corrects the article DOI 10.2196/26145.].This work presents a novel methodology for systematically processing the time series that report the number of positive, recovered and deceased cases from a viral epidemic, such as Covid-19. The main objective is to unveil the evolution of the number of real infected people, and consequently to predict the peak of the epidemic and subsequent evolution. For this purpose, an original nonlinear model relating the raw data with the time-varying geometric ratio of infected people is elaborated, and a Kalman Filter is used to estimate the involved state variables. A hypothetical simulated case is used to show the adequacy and limitations of the proposed method. Then, several countries, including China, South Korea, Italy, Spain, U.K. and the USA, are tested to illustrate its behavior when real-life data are processed. The results obtained clearly show the beneficial effect of the severe lockdowns imposed by many countries worldwide, but also that the softer social distancing measures adopted afterwards have been almost always insufficient to prevent the subsequent virus waves.Human computer interaction (HCI) involves a multidisciplinary fusion of technologies, through which the control of external devices could be achieved by monitoring physiological status of users. However, physiological biosignals often vary across users and recording sessions due to unstable physical/mental conditions and task-irrelevant activities. To deal with this challenge, we propose a method of adversarial feature encoding with the concept of a Rateless Autoencoder (RAE), in order to exploit disentangled, nuisance-robust, and universal representations. Belnacasan price We achieve a good trade-off between user-specific and task-relevant features by making use of the stochastic disentanglement of the latent representations by adopting additional adversarial networks. The proposed model is applicable to a wider range of unknown users and tasks as well as different classifiers. Results on cross-subject transfer evaluations show the advantages of the proposed framework, with up to an 11.6% improvement in the average subject-transfer classification accuracy.This study investigates the bipartite fixed-time time-varying output formation-containment tracking issue for heterogeneous linear multiagent systems with multiple leaders. Both cooperative communication and antagonistic communication between neighbor agents are taken into account. First, the bipartite fixed-time compensator is put forward to estimate the convex hull of leaders' states. Different from the existing techniques, the proposed compensator has the following three highlights 1) it is continuous without involving the sign function, and thus, the chattering phenomenon can be avoided; 2) its estimation can be achieved within a fixed time; and 3) the communication between neighbors can not only be cooperative but also be antagonistic. Note that the proposed compensator is dependent on the global information of network topology. To deal with this issue, the fully distributed adaptive bipartite fixed-time compensator is further proposed. It can estimate not only the convex hull of leaders' states but also the leaders' system matrices. Based on the proposed compensators, the distributed controllers are then developed such that the bipartite time-varying output formation-containment tracking can be achieved within a fixed time. Finally, two examples are given to illustrate the feasibility of the main theoretical findings.Image retrieval is a challenging problem that requires learning generalized features enough to identify untrained classes, even with very few classwise training samples. In this article, to obtain generalized features further in learning retrieval data sets, we propose a novel fine-tuning method of pretrained deep networks. In the retrieval task, we discovered a phenomenon in which the loss reduction in fine-tuning deep networks is stagnated, even while weights are largely updated. To escape from the stagnated state, we propose a new fine-tuning strategy to roll back some of the weights to the pretrained values. The rollback scheme is observed to drive the learning path to a gentle basin that provides more generalized features than a sharp basin. In addition, we propose a multihead ensemble structure to create synergy among multiple local minima obtained by our rollback scheme. Experimental results show that the proposed learning method significantly improves generalization performance, achieving state-of-the-art performance on the Inshop and SOP data sets.
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