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New Healing Approaches along with Biomarkers regarding Increased Healthspan.
In this study, nanocellulose/nanochitin membranes were prepared by suction filtrating 2,2,6,6-tetramethylpiperidine-1-oxyl-oxidized cellulose nanofiber (TOCNF)/partially deacetylated α-chitin nanofiber (α-DECHN) mixed suspensions. The result shows that, with a 11 ratio of nanocellulose to nanochitin, the tensile strength of the obtained composite membrane reaches 115.7 MPa and its light transmittance is 77.6 %. Heptadecafluoro-1,1,2,2-tetrahydrodecyl dimethylchlorosilane (HFTD) modified nano SiO2 (F-SiO2), was utilized to construct rough micro/nanostructures on the surfaces of the composite membranes by screen printing, forming high-strength, transparent and superhydrophobic nanocellulose/nanochitin membranes. Atomic force microscope (AFM) images reveal that nanocellulose and nanochitin, with the width between 5 nm and 20 nm and the length between 400 nm and 1.1 μm, are crosslinked with each other. The superhydrophobic nanocellulose/nanochitin composite membranes functionalized with a 2.0 wt% F-SiO2 suspension has a few clusters on its surface. The contact angle of this membrane is 150.1°, and its light transmittance is 70.4 %.Nanobiocomposite adsorptive membranes were engineered by integrating metal-organic frameworks (ZIF-8), into the chitosan/poly(vinyl alcohol) blend and coating the blend on PVDF membrane support for an enhanced separation performance. The membranes were characterized by SEM, AFM, BET, XRD, ATR-FTIR and tensile stress analyses. The central composite design was utilized to optimize the water flux and dye rejection. Using CCD, the effect of the membrane thickness, PEG (pore-former), and chitosan content on the flux and rejection were studied. The optimal conditions were obtained as; 10 wt% PEG, 3 wt% chitosan, and 200 μm membrane thickness. The optimized flux and rejection were obtained 78.94 L m-2 h-1 and 90.3 %, respectively. The antifouling of the membranes was also examined by the filtration of BSA protein solution. The membranes showed comparable performance; however, extremely higher permeability (78.94 L m-2 h-1 bar -1) compared to similar TFC membranes that guarantee the economic favorability of the filtration process.The development of minimally invasive surgery has created a demand for ideal medical adhesives exhibiting biocompatibility, biodegradability, antimicrobial activity, and strong adhesion to tissues in wet environments. However, as clinically approved surgical tissue glues suffer from poor adhesion activation, limited adhesion strength, and toxicity, novel tissue glues are highly sought after. Diphenhydramine purchase Herein, a mussel-inspired injectable hydrogel was prepared from catechol- and methacrylate-modified chitosan/gelatin and shown to exhibit biocompatibility, inherent antimicrobial activity, and good adhesion to wet tissues. Moreover, as this gel could be applied onto tissue surfaces and cured in situ within seconds of body contact by a biocompatible and multifunctional redox initiator (H2O2-ascorbic acid), it was concluded to be a promising surgical sealant and wound dressing (even for infected wounds) accelerating wound healing.Membrane technology is one of the most promising technologies for wastewater remedy. However, it remains challenging to prepare high-performance membrane matrix for complex pollutants, e.g. containing both oil and organic dye. In this work, we facilely fabricate a cellulose-fiber-supported MOF photocatalytic membrane, namely Ag@AgCl@MIL-100(Fe)/CCF, which was prepared via carboxymethylation of cotton fabric (CCF) as scaffold and in-situ synthesis of MOF derivative as photocatalyst. The carboxymethylation significantly improves the hydrophilicity of cotton fabric and the deposition amount of MIL-100(Fe). The high hydrophilicity of modified CCF and porous MIL-100(Fe) further enable the membrane with an efficient adsorption capacity of dyes and underwater oleophobicity against oils. The photocatalysts Ag@AgCl nanoparticles anchored onto MIL-100(Fe) promote the photocatalytic activity. As a result, the membrane shows simultaneous high removal efficiency towards dyes (97.3 %) and oils (99.64 %). Additionally, thanks to the good photocatalytic activity against organic pollutants, the membrane exhibits excellent self-cleaning and a long-term reuse capacity.Chitosan and chitin are categorized as low cost, renewable and eco-friendly biopolymers. However, they have low mechanical properties and unfavorable pore properties in terms of low surface area and total pore volume that limit their adsorption application. Many studies have shown that such weaknesses can be avoided by preparation of composites with carbonaceous materials from these biopolymers. This article provides a systematic review on the preparation of chitosan/chitin-carbonaceous material composites. Commonly used carbonaceous materials such as activated carbon, biochar, carbon nanotubes, graphene oxide and graphene to prepare composites are discussed. The application of chitosan/chitin-carbonaceous material composites for the adsorption of various water pollutants, and the regeneration and reusability of adsorbents are also included. Finally, the challenges and future prospects for the adsorbents applied for the adsorption of water pollutants are summarized.Natural polymeric hydrogel featuring multifunctional properties is more attractive as wound dressing. Herein, Tannic acid (TA)-reinforced methacrylated chitosan (CSMA)/methacrylated silk fibroin (SFMA) hydrogels were fabricated by two-step method of photopolymerization and TA solution incubating treatment. The TA in hydrogels not only served as second crosslinker improving the mechanical performance of up to a 5-fold increase (5 % TA treatment) than the pristine one, but also as functional molecule that endowed the hydrogels with enhanced adhesiveness and antioxidative properties. Besides, the introduction of TA into hydrogels further improved the antimicrobial activities against both Escherichia coli (E. coli) and Staphylococcus Aureus (S. aureus), as well as the cytocompatibility on fibroblasts. Moreover, it was demonstrated that the TA-treated CSMA/SFMA hydrogels could significantly promote wound healing in a full-thickness skin defect model. Collectively, these results showed that TA-reinforced CSMA/SFMA hydrogels could be a promising candidate as wound dressing.
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