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CAP1 holds and stimulates adenylyl cyclase in mammalian cellular material.
Implications of our results on cardiac physiology are also discussed.We introduce and study a simple model for the dynamics of voting intention in a population of agents that have to choose between two candidates. The level of indecision of a given agent is modeled by its propensity to vote for one of the two alternatives, represented by a variable p∈[0,1]. When an agent i interacts with another agent j with propensity p_j, then i either increases its propensity p_i by h with probability P_ij=ωp_i+(1-ω)p_j, or decreases p_i by h with probability 1-P_ij, where h is a fixed step. We assume that the interactions form a complete graph, where each agent can interact with any other agent. We analyze the system by a rate equation approach and contrast the results with Monte Carlo simulations. We find that the dynamics of propensities depends on the weight ω that an agent assigns to its own propensity. When all the weight is assigned to the interacting partner (ω=0), agents' propensities are quickly driven to one of the extreme values p=0 or p=1, until an extremist absorbing consensus is achieved. However, for ω>0 the system first reaches a quasistationary state of symmetric polarization where the distribution of propensities has the shape of an inverted Gaussian with a minimum at the center p=1/2 and two maxima at the extreme values p=0,1, until the symmetry is broken and the system is driven to an extremist consensus. A linear stability analysis shows that the lifetime of the polarized state, estimated by the mean consensus time τ, diverges as τ∼(1-ω)^-2lnN when ω approaches 1, where N is the system size. Finally, a continuous approximation allows us to derive a transport equation whose convection term is compatible with a drift of particles from the center toward the extremes.A numerical procedure based on the Schwarz-Christoffel map suitable for the study of the Laplacian growth of thin two-dimensional protrusions is presented. The protrusions take the form of either straight needles or curved fingers satisfying Loewner's equation, and are represented by slits in the complex plane. Particular use is made of Driscoll's numerical procedure, the SC Toolbox, for computing the Schwarz-Christoffel map from a half plane to a slit half plane. Since the Schwarz-Christoffel map applies only to polygonal regions, the growth of curved fingers is approximated by an increasing number of short straight line segments. The growth rate is given by a fixed power η of the harmonic measure at the finger or needle tips and so includes the possibility of "screening" as the needles of fingers interact with themselves and with boundaries. The method is illustrated with examples of multiple needle and finger growth in half-plane and channel geometries. The effect of η on the trajectories of asymmetric bifurcating fingers is also studied.Most treatments of electron-electron correlations in dense plasmas either ignore them entirely (random phase approximation) or neglect the role of ions (jellium approximation). In this work, we go beyond both these approximations to derive a formula for the electron-electron static structure factor which properly accounts for the contributions of both ionic structure and quantum-mechanical dynamic response in the electrons. The result can be viewed as a natural extension of the quantum Ornstein-Zernike theory of ionic and electronic correlations, and it is suitable for dense plasmas in which the ions are classical and the conduction electrons are quantum-mechanical. The corresponding electron-electron pair distribution functions are compared with the results of path integral Monte Carlo simulations, showing good agreement whenever no strong electron resonance states are present. We construct approximate potentials of mean force which describe the effective screened interaction between electrons. Significant deviations from Debye-Hückel screening are present at temperatures and densities relevant to high-energy density experiments involving warm and hot dense plasmas. The presence of correlations between conduction electrons is likely to influence the electron-electron contribution to the electrical and thermal conductivity. It is expected that excitation processes involving the conduction electrons (e.g., free-free absorption) will also be affected.This paper is the continuation of work done in our previous papers [A. A. Doinikov et al., Phys. Rev. E 100, 033104 (2019)2470-004510.1103/PhysRevE.100.033104; Phys. Rev. E 100, 033105 (2019)].2470-004510.1103/PhysRevE.100.033105 The overall aim of the study is to develop a theory for modeling the velocity field of acoustic microstreaming produced by nonspherical oscillations of an acoustically driven gas bubble. In our previous papers, general equations have been derived to describe the velocity field of acoustic microstreaming produced by modes m and n of bubble oscillations. After solving these general equations for some particular cases of modal interactions (cases 0-n, 1-1, and 1-m), in this paper the general equations are solved analytically for the case that acoustic microstreaming results from the self-interaction of an arbitrary surface mode n≥1. Solutions are expressed in terms of complex mode amplitudes, meaning that the mode amplitudes are assumed to be known and serve as input data for the calculation of the velocity field of acoustic microstreaming. No restrictions are imposed on the ratio of the bubble radius to the viscous penetration depth. The self-interaction results in specific streaming patterns a large-scale cross pattern and small recirculation zones in the vicinity of the bubble interface. Particularly the spatial organization of the recirculation zones is unique for a given surface mode and therefore appears as a signature of the n-n interaction. Experimental streaming patterns related to this interaction are obtained and good agreement is observed with the theoretical model.We study the planar motion of telegraphic processes. We derive the two-dimensional telegrapher's equation for isotropic and uniform motions starting from a random walk model which is the two-dimensional version of the multistate random walk with a continuum number of states representing the spatial directions. BAY-805 We generalize the isotropic model and the telegrapher's equation to include planar fractional motions. Earlier, we worked with the one-dimensional version [Masoliver, Phys. Rev. E 93, 052107 (2016)PREHBM2470-004510.1103/PhysRevE.93.052107] and derived the three-dimensional version [Masoliver, Phys. Rev. E 96, 022101 (2017)PREHBM2470-004510.1103/PhysRevE.96.022101]. An important lesson is that we cannot obtain the two-dimensional version from the three-dimensional or the one-dimensional one from the two-dimensional result. Each dimension must be approached starting from an appropriate random walk model for that dimension.
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