Notes

A Review: Finding One,Three,4-oxadiazole along with chalcone nucleus pertaining to cytotoxicity/EGFR inhibitory anticancer task.
High action, high voltage closing switches are the key components of pulsed power systems based on high energy capacitor banks, primarily used for high power lasers, electromagnetic accelerators, high pulsed magnetic field facilities, crushing materials, and electromagnetic compatibility tests. There are several options for closing switches, including ignitrons, vacuum switches, pseudo-spark switches, solid-state switches, and high pressure gas switches (spark gaps). Spark switches are currently the most used due to their relatively simple design, reliability, and ease of maintenance and repair. The main disadvantage of spark gaps is a limited lifetime, which is directly or indirectly related to the erosion of the electrodes. To prevent erosion of the electrodes, multichannel switches and switches with movement of the discharge channel were proposed. In this Review, both types of switches are considered.In this Note, we discuss the Helmholtz spacing for a pair of thin rectangular coils of arbitrary aspect ratio and consider how best to use such coils to compensate for Earth's magnetic field along the coils' Cartesian symmetry axes. Such coils are frequently used in conjunction with charged-particle beam machines. The Helmholtz spacing varies non-monotonically between that for square coils and that for four optimally spaced infinite wires. We consider other coil spacings that extend the length over which the field varies by less than some tolerance along the Cartesian symmetry axes. The calculations also provide a convenient means to evaluate when the length of the coils is sufficiently long to be considered infinite at the center point within a fixed tolerance.A structure that consists of a λ/4 stepped-impedance microstrip resonator is proposed as an instrument for the investigation of nonlinear effects in thin magnetic films and also can be used as a microwave frequency doubler. A conversion efficiency of 0.65% is observed at a one-layer 100 nm Ni80Fe20 thin film at an input signal level of 4.6 W for a 1 GHz probe signal. The maximum measured conversion efficiency (1% at 1 GHz) was achieved for the 9-layer Ni80Fe20 film where 150 nm magnetic layers were separated by SiO2 layers.We present the design and construction of a new experimental apparatus for the trapping of single Ba+ ions in the center of curvature of an optical-quality hemispherical mirror. We describe the layout, fabrication, and integration of the full setup, consisting of a high-optical access monolithic "3D-printed" Paul trap, the hemispherical mirror, a diffraction-limited in-vacuum lens (NA = 0.7) for collection of atomic fluorescence, and a state-of-the art ultra-high vacuum vessel. This new apparatus enables the study of quantum electrodynamics effects such as strong inhibition and enhancement of spontaneous emission and achieves a collection efficiency of the emitted light in a single optical mode of 31%.The uncertainty of the ac Stark shift due to thermal radiation represents a major contribution to the systematic uncertainty budget of state-of-the-art optical atomic clocks. In the case of optical clocks based on trapped ions, the thermal behavior of the rf-driven ion trap must be precisely known. This determination is even more difficult when scalable linear ion traps are used. Such traps enable a more advanced control of multiple ions and have become a platform for new applications in quantum metrology, simulation, and computation. Nevertheless, their complex structure makes it more difficult to precisely determine its temperature in operation and thus the related systematic uncertainty. click here We present here scalable linear ion traps for optical clocks, which exhibit very low temperature rise under operation. We use a finite-element model refined with experimental measurements to determine the thermal distribution in the ion trap and the temperature at the position of the ions. The trap temperature is investigated at different rf-drive frequencies and amplitudes with an infrared camera and integrated temperature sensors. We show that for typical trapping parameters for In+, Al+, Lu+, Ca+, Sr+, or Yb+ ions, the temperature rise at the position of the ions resulting from rf heating of the trap stays below 700 mK and can be controlled with an uncertainty on the order of a few 100 mK maximum. The corresponding uncertainty of the trap-related blackbody radiation shift is in the low 10-19 and even 10-20 regime for 171Yb+(E3) and 115In+, respectively.Residual or induced strains are important factors in the performance of electronic devices, actuators, and sensors. In this paper, we report the application of digital speckle shearography to obtain the two-dimensional field-induced out-of-plane strain maps in a piezoelectric slab under a varying electric field. Both the free-standing and loaded (pinned) states are investigated. The results show field-dependent strain maps with parabolic profiles on the order of 10-4 and 10-3 in the free-standing and pinned states, respectively, in agreement with typical values for piezoelectric ceramics. This study provides a simple, non-destructive, and full-field method to characterize these materials.Widespread transmission of a novel coronavirus, COVID-19, has caused major public health and economic problems around the world. Significant mitigation efforts have been implemented to reduce the spread of COVID-19 but the role of ambient noise and elevated vocal effort on airborne transmission have not been widely reported. Elevated vocal effort has been shown to increase emission of potentially infectious respiratory droplets, which can remain airborne for up to several hours. Multiple confirmed clusters of COVID-19 transmission were associated with settings where elevated vocal effort is generally required for communication, often due to high ambient noise levels, including crowded bars and restaurants, meat packing facilities, and long-stay nursing homes. Clusters of COVID-19 transmission have been frequently reported in each of these settings. Therefore, analysis of COVID-19 transmission clusters in different settings should consider whether higher ambient noise levels, which are associated with increased vocal effort, may be a contributing factor in those settings.
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