Notes

Fat, non-eosinophilic asthma attack: frequent exacerbators within a real-world setting.
No studies have analyzed the longitudinal associations of change in physical fitness components and obesity with academic performance. The aim of the study was to examine longitudinal associations of changes in physical fitness components and body mass index with academic performance among youth, and whether the physical fitness components are moderators of the longitudinal association between obesity and academic performance in youth. Longitudinal analyses (2 years) included 1802 youths. Physical fitness components were assessed following the ALPHA health-related fitness test battery. Academic performance was assessed via school records. Youth in the persistently high cardiorespiratory fitness and motor ability categories (ie, fit at baseline and at 2-year follow-up) had higher academic performance at follow-up than those in the persistently low category. Further, youth with normal weight at baseline and overweight/obesity at follow-up had lower academic performance scores at follow-up compared to those with normal weight. Also, cardiorespiratory fitness may ameliorate the negative influence of excess body mass index on academic performance at follow-up. Promoting physical activity programs at school that include both aerobic exercise and motor tasks to improve physical fitness and reduce body mass index may not only improve physical health, but also contribute toward successful academic development.
STIs present a significant threat to individual and public health, disproportionately affecting youth. The study aimed to evaluate (a) the prevalence of asymptomatic Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections among youth using a rapid assay platform, (b) the participants' sexual behaviour and STI knowledge, (c) the utility of the rapid assay in reducing diagnosis-to-treatment time.

In this study, 272 subjects (14-31years) were included between 12/2016 and 7/2018. A questionnaire was used to collect sociodemographic data, sexual behaviour and STI knowledge. selleck chemical Prevalence of CT and NG infections were tested from oral, vaginal and anal swabs for women and oral, anal swabs and urine for men, using the Cepheid Xpert
CT/NG assay. Time intervals between (i) test to the time the patient were informed of the result (turn around time - TAT) and (ii) test to therapy initiation was documented.

Of the 272 subjects (48.9% female, 48.9% male, undisclosed 2.2%), 56.6 % reported university educahan a day.This study aimed (a) to estimate the transition rate for top 50 ranked track and field jumpers, (b) to compare the performance progression of top 50 ranked senior jumpers (top50 senior) to those who failed to be top 50 ranked in the senior category despite being top 50 ranked in the under 18 category (only U18), and (c) to verify whether relative age effect may at least partially explain the differences in the two above-mentioned subgroups. The career performance trajectories of 5981 athletes (2837 females) competing in jump events from 2000 to 2019 were extracted from the World Athletics database. The all-time top 50 ranked athletes for each age from 16 years to senior category were identified. Performance progression characteristics were compared using linear mixed-effects model. Only 8% of males and 16% of females top 50 ranked at the age of 16 years managed to be included among the top50 senior. Only U18subgroup made the first appearance in the database (at 15-16 years) and reached the peak performance (at 20 years) earlier than top50 senior (17-18 and 26-27 years, respectively). The relative age effect was largely present in Only U18 but not in top50 senior subgroups. Most of the early-successful U18 world-class jumpers did not manage to maintain the same level of competitiveness in adulthood since they experienced a plateau in performance from 20 years of age. Conversely, top 50 ranked senior jumpers continued to produce consistent performance improvement up to 26-27 years of age.In almost all countries worldwide, wearing a mask is mandatory in public places, public transportation services and in hospitals and is strongly recommended in other open or closed areas to avoid the transmission of coronavirus.Invited for the cover of this issue is Sergiusz Luliński and his co-workers from Warsaw University of Technology and University of Warsaw. The image depicts a journey through the interior of the porous Covalent Organic Framework containing phosphorus and boron centres with carbon dioxygen trapped inside an imagined cave. Read the full text of the article at 10.1002/chem.202001960.
Consumption of fava beans seeds can be harmful to both humans and animals due to the presence of pyrimidine glucosides vicine and convicine. Therefore, seeds, feed supplements, and protein extracts derived from fava beans should be monitored for the contents of pyrimidine derivatives.

The main objective of this work was the development and validation of an inexpensive, uncomplicated, quick, and robust method for the quantitation of vicine and convicine in seeds of fava beans.

Plant material was extracted using a dual-phase extraction system to remove lipophilic contaminants and deactivate residual enzymes. Pyrimidine glucosides together with the internal standard 5-bromouridine were separated using capillary zone electrophoresis (CZE) on an uncoated fused-silica capillary with alkaline, tetraborate-based electrolyte. Linearity, limits of detection and quantitation, precision, accuracy, recovery, and robustness of the method were investigated. The method was applied for quantitation of pyrimidine glucosides in seeds.

Validation results suggest that the method is suitable for quantitation of pyrimidine glucosides, although it may not be sensitive enough for low-concentrated samples. Application of the method showed that seeds of the investigated variety of fava beans contain both vicine at 10-15 mg/g of dry weight and convicine at 3-5 mg/g of dry weight.

Developed and validated CZE-ultraviolet (UV) method is suitable for analysis of pyrimidine glucosides in seeds of Vicia faba L. var. minor. It can be used as an inexpensive, greener alternative to more advanced methods while providing equally reliable and accurate results.
Developed and validated CZE-ultraviolet (UV) method is suitable for analysis of pyrimidine glucosides in seeds of Vicia faba L. var. minor. It can be used as an inexpensive, greener alternative to more advanced methods while providing equally reliable and accurate results.
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