Notes

Dual connection between 9-cis retinoic acidity on ACTH-dependent hyperplastic adrenal tissue.
found between the "sexual health" score and the total FSFI score.

The Pelvi-Perineal Surgery Sexuality Questionnaire (PPSSQ) is a 13-question self-questionnaire validated in a population of sexually active women or not, operated on for stress urinary incontinence or pelvic organ prolapse by laparoscopy or vaginal surgery, with or without mesh.

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Despite considerable individual differences in the vulnerability vs resistance to effects of sleep loss, there is no practical self-report tool to predict these differences across domains and only limited evidence whether they are general or domain-specific. To address this need, we developed the Iowa Resistance to Sleeplessness Test (iREST).

A construct-validation approach was employed. During the substantive phase, self-report items were generated to capture vulnerability vs resistance to sleep loss across various psycho-behavioral domains. During the structural phase, analyses identified the underlying factor structure and examined reliability of individual scale scores. Finally, the external phase used convergent and discriminant analyses to evaluate the factors in light of related sleep and personality measures, and tested criterion validity of the scale scores in predicting neurocognitive and affective responses to experimental sleep restriction (Total N = 1018).

Analyses yielded discriminant and reliable scale scores that reflected resistance across cognitive, affective, and somatic responses, while also marking a general resistance factor. Convergent and discriminant probes revealed moderate associations of scale scores with daytime sleepiness and sleep-related distress, but small to negligible associations with other measures of sleep behavior, perceptions, and personality. Critically, criterion analyses yielded validity evidence for predicting cognitive and affective impairments in response to experimental sleep loss.

Scores on the iREST show validity in capturing cognitive and affective resistance to moderate sleep loss among young adults, supporting its further exploration as a practical tool for predicting behavior due to lost sleep.
Scores on the iREST show validity in capturing cognitive and affective resistance to moderate sleep loss among young adults, supporting its further exploration as a practical tool for predicting behavior due to lost sleep.
We and others have found that couples' sleep is a shared and dyadic process. Couples' sleep-wake concordance (whether couples are awake or asleep at the same time) is associated with couples' relationship factors; however, we know little of the temporal associations between concordance and daily relationship characteristics. The purpose of this study was to examine daily positive and negative interpersonal interactions to determine how they predict, and are predicted by, nightly sleep-wake concordance.

Participants were 48 heterosexual couples between 18 and 45 years of age who shared a bed with their spouse. Couples completed questionnaires and daily assessments of positive and negative interactions. Each member of the dyad wore wrist actigraphs for 10 days. Sleep-wake concordance was calculated as the percentage of time couples were awake or asleep throughout the night at one-minute intervals. Multilevel modeling with lagged effects determined bidirectional and lagged associations between concordance antcomes.Alimentary limb kinking after laparoscopic Roux-en-Y gastric bypass suggested by CT-scan and diagnosed at laparoscopic surgery. Surgical treatment principles.
To conduct a survey of current practice in the management of obstetrical anal sphincter injuries (OASI) and to compare short, medium and long-term practices according to the specialty of the surgeon.

A 50-item questionnaire was addressed by mail to various specialists via the national learned societies. The questionnaire was addressed only to practitioners who currently managed OASI in their practice.

Of the 135 healthcare professionals who responded, 57 were sub-specialists in ano-rectal surgery (42.2%) and 78 were obstetrical or gynecological specialists (OB-GYN) (57.8%). Management in the acute period after OASI was similar among the specialties and 50% of the practitioners did not perform suture repair of the internal sphincter. Furthermore, few gynecological specialists recommended systematic consultation with an ano-rectal specialist during acute management. In the medium term, ano-rectal specialists were more likely to explore gastro-intestinal symptoms, either clinically or through para-clinical studies. However, these studies did not systematically lead to interventional management in the absence of consensus, particularly for medium-term sphincter repair. In addition, 25% of practitioners recommended that patients undergo systematic delivery by caesarean section for further pregnancies after OASI. In the long term (>12 months), there were substantial differences in management of OASI not only between specialties but also within the same specialty.

The various specialists should coordinate to propose multidisciplinary recommendations on the management of OASI.
The various specialists should coordinate to propose multidisciplinary recommendations on the management of OASI.
We know that inflammation is related to colorectal cancer prognosis and to the onset of postoperative infections.

This study aimed to understand the relationship between preoperative inflammation and the prognosis of colorectal cancer and to elucidate whether the impact of inflammation on cancer prognosis was related to an increased risk of surgical infection or was independent of it.

Patients who underwent elective colorectal cancer surgery between November 2011 and April 2014 were included in a prospective database (IMACORS). Preoperative c reactive protein was collected for each patient. Patients were followed up according to the French national guidelines. A cut-off of preoperative CRP of 5mg/L was chosen. Clinical characteristics were compared according to CRP using Chi
and Mann-Whitney tests. LY2228820 The Overall Survival (OS) and Disease-Free-Survival (DFS) were compared by Kaplan-Meier curves. A Cox proportional hazards regression model was applied to perform a multivariate analysis of OS and DFS's predictors.
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