Notes

Marketplace analysis genetic examines present clues regarding pill switching within Streptococcus suis 2 stresses with different virulence levels and also hereditary backdrops.
The fermion doubling theorem plays a pivotal role in Hermitian topological materials. It states, for example, that Weyl points must come in pairs in three-dimensional semimetals. Here, we present an extension of the doubling theorem to non-Hermitian lattice Hamiltonians. We focus on two-dimensional non-Hermitian systems without any symmetry constraints, which can host two different types of topological point nodes, namely, (i) Fermi points and (ii) exceptional points. We show that these two types of protected point nodes obey doubling theorems, which require that the point nodes come in pairs. To prove the doubling theorem for exceptional points, we introduce a generalized winding number invariant, which we call the "discriminant number." Importantly, this invariant is applicable to any two-dimensional non-Hermitian Hamiltonian with exceptional points of arbitrary order and, moreover, can also be used to characterize nondefective degeneracy points. Furthermore, we show that a surface of a three-dimensional system can violate the non-Hermitian doubling theorems, which implies unusual bulk physics.Exceptional points (EPs) of a non-Hermitian Hamiltonian with parity-time-reversal (PT) symmetry have the potential to drastically enhance the capabilities of metrology and sensing through their power-law growing sensitivity to external perturbation. With the ability of generating and tuning dissipation in a single trapped ion system, we observe rich dynamics and detailed quantum phase transitions from the PT-symmetric phase to the symmetry-breaking phase. In this single qubit full quantum system, we develop a method to precisely determine the location of EP without any fitting parameter, and extract the eigenvalues in a unified way through all parameter regions. We can also obtain the full density matrix by quantum state tomography. Finally, we suggest from theoretical analysis that the periodically driving PT-symmetric non-Hermitian system can be used to measure the magnitude, frequency, and phase of time-dependent perturbation with EP enhancement.We introduce a simple physical picture to explain the process of molecular sorting, whereby specific proteins are concentrated and distilled into submicrometric lipid vesicles in eukaryotic cells. To this purpose, we formulate a model based on the coupling of spontaneous molecular aggregation with vesicle nucleation. Its implications are studied by means of a phenomenological theory describing the diffusion of molecules toward multiple sorting centers that grow due to molecule absorption and are extracted when they reach a sufficiently large size. The predictions of the theory are compared with numerical simulations of a lattice-gas realization of the model and with experimental observations. The efficiency of the distillation process is found to be optimal for intermediate aggregation rates, where the density of sorted molecules is minimal and the process obeys simple scaling laws. Quantitative measures of endocytic sorting performed in primary endothelial cells are compatible with the hypothesis that these optimal conditions are realized in living cells.The rupture of a polymer chain maintained at temperature T under fixed tension is prototypical to a wide array of systems failing under constant external stress and random perturbations. Past research focused on analytic and numerical studies of the mean rate of collapse of such a chain. Surprisingly, an analytic calculation of the probability distribution function (PDF) of collapse rates appears to be lacking. Since rare events of rapid collapse can be important and even catastrophic, we present here a theory of this distribution, with a stress on its tail of fast rates. We show that the tail of the PDF is a power law with a universal exponent that is theoretically determined. Extensive numerics validate the offered theory. Lessons pertaining to other problems of the same type are drawn.Mode locking in lasers is a collective effect, where due to a weak coupling a large number of frequency modes lock their phases to oscillate in unison, forming an ultrashort pulse in time. We demonstrate an analogous collective effect in coupled parametric oscillators, which we term "pairwise mode locking," where many pairs of modes with twin frequencies (symmetric around the center carrier) oscillate simultaneously with a locked phase sum, while the phases of individual modes remain undefined. Thus, despite being broadband and multimode, the emission is not pulsed and lacks first-order coherence, while possessing a very high degree of second-order coherence. SN 52 in vitro Our configuration comprises two coupled parametric oscillators within identical multimode cavities, where the coupling between the oscillators is modulated in time at the repetition rate of the cavity modes, with some analogy to active mode locking in lasers. We demonstrate pairwise mode locking in a radio-frequency experiment, covering over an octave of bandwidth with approximately 20 resonant mode-locked pairs, filling most of the available bandwidth between dc and the pump frequency. We accompany our experiment with an analytic model that accounts for the properties of the coupled parametric oscillators near threshold.We characterize metrologically useful multipartite entanglement by representing partitions with Young diagrams. We derive entanglement witnesses that are sensitive to the shape of Young diagrams and show that Dyson's rank acts as a resource for quantum metrology. Common quantifiers, such as the entanglement depth and k-separability are contained in this approach as the diagram's width and height. Our methods are experimentally accessible in a wide range of atomic systems, as we illustrate by analyzing published data on the quantum Fisher information and spin-squeezing coefficients.The energy dissipation rate in a nonequilibrium reaction system can be determined by the reaction rates in the underlying reaction network. By developing a coarse-graining process in state space and a corresponding renormalization procedure for reaction rates, we find that energy dissipation rate has an inverse power-law dependence on the number of microscopic states in a coarse-grained state. The dissipation scaling law requires self-similarity of the underlying network, and the scaling exponent depends on the network structure and the probability flux correlation. Existence of the inverse dissipation scaling law is shown in realistic biochemical systems such as biochemical oscillators and microtubule-kinesin active flow systems.
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