Notes

First Discovery associated with Post-Surgical Difficulties using Time-series Electronic Health Records.
The purpose of this study was to investigate the accuracy of removable partial denture frameworks fabricated by 3D-printed pattern casting (AM-Cast) and selective laser sintering (SLS) under different co nditions with a reinforcement bar.

A partially edentulous model was scanned with a dental laboratory scanner, and CAD software was used to design the framework. Reinforcement bars (n=0-2) were set on the lingual side of the framework. 3D scanning of the fabricated frameworks by AM-Cast and SLS was performed, and the obtained data were overlapped with the design data. The differences in shape among setting conditions of the bar were statistically compared using the Bonferroni method after the Kruskal-Wallis test.

The ranges in differences of the AM-Cast-0, AM-Cast-1, and AM-Cast-2 were -0.167 to 0.128 mm, -0.101 to 0.105 mm, and -0.185 to 0.015 mm, respectively. The ranges of SLS-0, SLS-1, and SLS-2 were -0.166 to 0.035 mm, -0.182 to 0.049 mm, and -0.138 to 0.038 mm, respectively. Large discrepancies were observed at the joining area of the lingual bar on the right side of the AM-Cast. A significant difference was found between the AM-Cast-0 and AM-Cast-1, and between the AM-Cast-0 and AM-Cast-2.

The setting conditions of the reinforcement bar affected the accuracy of the lingual bar in the AM-Cast; however, no effect was observed on the displacement of the central area of the lingual bar in SLS. Setting a single reinforcing bar on the retentive latticework contributed to improving the accuracy of the lingual bar in the AM-Cast but not the displacement of the central area of the lingual bar in SLS.
The setting conditions of the reinforcement bar affected the accuracy of the lingual bar in the AM-Cast; however, no effect was observed on the displacement of the central area of the lingual bar in SLS. Setting a single reinforcing bar on the retentive latticework contributed to improving the accuracy of the lingual bar in the AM-Cast but not the displacement of the central area of the lingual bar in SLS.
In this study, we aimed to investigate the effect of glucose metabolism on bone healing after tooth extraction in an osteoporosis rat model administered zoledronic acid (ZA) and dexamethasone (DX).

In total, 24 male Wistar rats (4 weeks old) were randomly assigned to four groups Control (subcutaneous physiological saline), ZD (subcutaneous ZA and DX twice a week), Ins+ZD (subcutaneous insulin followed by ZD treatment), and Met+ZD (oral metformin followed by ZD treatment). Blood was collected every two weeks . Two weeks after treatment initiation, the first molar tooth on the right maxilla was extracted from all rats. Four weeks later, the rats were sacrificed, and bone healing was assessed. Maxillae samples were fixed and scanned using micro-computed tomography for quantifying areas of bone defects. Hematoxylin-eosin and tartrate-resistant acid phosphatase (TRAP) staining were performed to evaluate bone apoptosis and osteoclast number.

In all experimental groups, body weight was statistically lower than that in the Control group, with no changes observed in uncarboxylated osteocalcin concentrations. The radiological analysis revealed that insulin or metformin administration improved healing in the tooth extraction socket (p < 0.01). Histological examination revealed that the osteonecrosis area was reduced in the Ins+ZD and Met+ZD groups (p < 0.01). TRAP staining presented increased osteoclast numbers in the ZD group when compared with that observed in the Control.

Tooth extraction with long-term ZA and DX administration inhibited bone remodeling and induced bisphosphonate-related osteonecrosis of the jaw-like lesions. Metformin exerted protective effects ag ainst osteonecrosis of the jaw.
Tooth extraction with long-term ZA and DX administration inhibited bone remodeling and induced bisphosphonate-related osteonecrosis of the jaw-like lesions. Metformin exerted protective effects ag ainst osteonecrosis of the jaw.
Wearing a sports mouthguard is not only recommended in collision sports, such as American football, boxing, and rugby football, but also in low-contact sports, such as basketball, handball, and soccer. It is recommended to remove oral prosthetic devices while playing sports to avoid the risk of fracturing the device. However, players with maxillectomy must wear obturator-type prosthetic devices for speech, breathing, and deglutition even while playing sports. Therefore, there is a need for an oral appliance to prevent dental injury while playing sports without the risk of fracturing the device for players who have undergone maxillectomy.In this case, we fabricated and proposed overlay-type and obturator-type customized sports mouthguards for a patient who had undergone maxillectomy and assessments of satisfaction, speech intelligibility, nasopharyngeal closure function, and swallowing function while playing soccer.

The patient was only satisfied with the obturator-type mouthguard, and the results of the speech intelligibility, nasopharyngeal closure function, and swallowing tests using the obturator-type mouthguard showed no differences compared to those associated with the previously used prosthetic device.

This case may help highlight the importance of providing obturator-type mouthguards for players who have undergone maxillectomy to prevent dental injury and physical and mental discomfort.
This case may help highlight the importance of providing obturator-type mouthguards for players who have undergone maxillectomy to prevent dental injury and physical and mental discomfort.
Sarcopenia has recently been attracting attention as an early sign of the need for nursing care in older adults. ATR inhibitor Some studies have reported that oral health is related to sarcopenia and its diagnostic factors (hand grip strength, walking speed, and skeletal muscle mass). However, the relationship between oral health and sarcopenia remains poorly investigated and no review to date has compiled the available research on this relationship. The aim of this review was to summarize the current evidence describing the association between oral health and sarcopenia.

The internet database PubMed was searched using various combinations of related and synonymous keywords for "oral" or "dental" or "oral health" or "oral function" and "sarcopenia" or "walking speed" or "hand grip strength" or "skeletal muscle mass." A total of 27 studies found to be eligible were critically evaluated and their key findings were summarized.

Most of the studies were cross-sectional and conducted in Japan. A wide range of oral factors, including number of teeth, occlusal support, periodontal state, occlusal force, mastication, tongue pressure, and swallowing, were covered.
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