Notes

From Buttocks to Braids as well as Ponytails: Coming into a fresh Era involving Female Army Hair-Grooming Criteria.
This study determined whether external workload could be anticipated during 5 vs. 5 games-based drills in basketball. Thirteen semi-professional, male basketball players were monitored during 5 vs. 5 training drills across the season. External workload was determined using PlayerLoad™ (AU∙min-1). The reference workload for each drill was calculated across all sessions, using bootstrapping. The bootstrap mean workload and 95% confidence intervals (CI) were then calculated for session 1, sessions 1-2, and continued for remaining sessions (1-3, 1-4, etc.), and were compared with those of the reference workload. The minimum sessions to anticipate workload for each drill was identified when the first normative value fell within ±5% or ±10% of the reference workload 95% CI. The minimum sessions were then tested to determine the accuracy to which workload could be anticipated. Three to four sessions were needed to anticipate workload within ±5%, while 2-3 sessions were needed to anticipate workload within ±10%. External workload was anticipated in 0-55% of future sessions using an error range of ±5%, and in 58-89% of sessions using an error range of ±10%. External workload during 5 vs. 5 games-based drills can be anticipated in most sessions using normative values established during a short-term monitoring period with an error range of ±10%.Heart disease is the leading cause of death worldwide. The major cause of heart failure is the death of the myocardium caused by myocardial infarction, detrimental cardiac remodeling, and cardiac fibrosis occurring after the injury. This study aimed at discovering the role of the anti-aging protein α-klotho (KL), which is the co-receptor of fibroblast growth factor-23 (FGF23), in cardiac regeneration, fibrosis, and repair. We found that the anti-apoptotic function of soluble KL in isoproterenol-treated H9c2 cardiomyocytes was independent of FGF23 in vitro. In vivo, isoproterenol-induced cardiac fibrosis and cardiomyocyte and endothelial cell apoptosis were reduced by KL treatment. Moreover, the number of Ki67-positive endothelial cells and microvessel density within the isoproterenol-injured myocardium were increased upon KL treatment. However, by using genetic fate-mapping models, no evident cardiomyocyte proliferation within the injured myocardium was detected with or without KL treatment. Collectively, the cardioprotective functions of KL could be predominantly attributed to its anti-apoptotic and pro-survival activities on endothelial cells and cardiomyocytes. KL could be a potential cardioprotective therapeutic agent with anti-apoptotic and pro-survival activities on cardiomyocytes and endothelial cells.Lectures are the most commonly used training method but may not be effective in communicating safety information among migrant workers because of language and cultural barriers. The comprehension of safety information is particularly urgent in highly hazardous sectors such as agriculture, which has a high migrant workforce rate. In this study, an ergonomic user-centred approach was adopted to develop and evaluate safety training material targeting migrants employed on Italian farms. Focus groups with both trainers and migrants were carried out to collect information on critical issues in traditional training material, the most and least comprehended topics and suggestions for training improvement. Based on the focus group analysis, the training material was developed considering several visual factors and more engaging interaction between trainers and migrant trainees. The usability of the developed material was then evaluated in a group of 20 migrant farmworkers through a questionnaire assessing the knowledge of safety information before (T0) and after (T1) the training (effectiveness), perceived effort in learning (efficiency) and user satisfaction after training. The results showed improved knowledge, low perceived effort and high satisfaction, pointing to the positive effects of active user involvement when designing targeted training materials.The identification of circulating proteins associated with relapse in pediatric Hodgkin lymphoma (HL) may help develop predictive biomarkers. We previously identified a set of predictive biomarkers by difference gel electrophoresis. Here we used label-free quantitative liquid chromatography-mass spectrometry (LC-MS/MS) on plasma collected at diagnosis from 12 children (age 12-16 years) with nodular sclerosis HL, including six in whom the disease relapsed within 5 years of treatment in the LH2004 trial. Zoligratinib inhibitor Plasma proteins were pooled in groups of three, separately for non-relapsing and relapsing HL, and differentially abundant proteins between the two disease states were identified by LC-MS/MS in an explorative and validation design. Proteins with a fold change in abundance >1.2 or ≤0.8 were considered "differentially abundant". LC-MS/MS identified 60 and 32 proteins that were more abundant in non-relapsing and relapsing HL plasma, respectively, in the explorative phase; these numbers were 39 and 34 in the validato therapy and provide new evidence about these proteins as possible biomarkers of relapse in pediatric HL.Previous results evidenced acute exposure to high altitude (HA) weakening the relation between daily melatonin cycle and the respiratory quotient. This review deals with the threat extreme environments pose on body time order, particularly concerning energy metabolism. Working at HA, at poles, or in space challenge our ancestral inborn body timing system. This conflict may also mark many aspects of our current lifestyle, involving shift work, rapid time zone crossing, and even prolonged office work in closed buildings. Misalignments between external and internal rhythms, in the short term, traduce into risk of mental and physical performance shortfalls, mood changes, quarrels, drug and alcohol abuse, failure to accomplish with the mission and, finally, high rates of fatal accidents. Relations of melatonin with energy metabolism being altered under a condition of hypoxia focused our attention on interactions of the indoleamine with redox state, as well as, with autonomic regulations. Individual tolerance/susceptibility to such interactions may hint at adequately dealing with body timing disorders under extreme conditions.
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