Notes

Propranolol Sensitizes Vascular Sarcoma Tissue to be able to Doxorubicin through Changing Lysosomal Medicine Sequestration as well as Substance Efflux.
.004) associated with milk production, indicating a non-linear relationship between milk yield and THI. The CSF model showed better goodness of fit and predictive ability than other models for predicting future population response of milk yield to heat stress in small holder dairy farms in Tanzania. Herd management strategies and animal husbandry measures are needed in small holder dairy farms in Tanzania to minimize the impact of heat stress on milk yield and income of the farmers.
Mindfulness training has been shown to reduce rates of depression, anxiety and perceived stress, but its impact on stress and emotion regulation in real-world settings in the college-aged population is unknown. This study examines the effect of an 8-session long mindfulness training on first-year college students' daily experiences of stress and emotion regulation.

Fifty-two first-year students were randomized to the mindfulness training or the waitlist-control group during the fall academic semester. Before, during and after the trial, students completed 10-days of ecological momentary assessments (EMA), reporting on family and school or work stress, negative emotion, rumination, and interference by unwanted thoughts and emotions up to four times a day. Multilevel regression analysis compared levels of momentary stress and emotion regulation difficulties, as well as the strength of the moment-level association between stress and emotion regulation, by intervention condition, before, during and after the nterventions.
Psychological and neural evidence suggests that negative attitudes toward stigmatized individuals arise in part from failures to perceive them as social targets. Here, we tested whether experimentally up-regulating neural regions involved in social cognition would predict subsequent decreases in bias toward stigmatized individuals (i.e., people who use substances).

Participants underwent fMRI while completing either a lovingkindness intervention task or a control task, and each task was reinforced via daily text messages for a month following the one-time fMRI scan. Changes in implicit bias against stigmatized individuals were measured by Implicit Association Tests.

The lovingkindness intervention task, compared to a control task, elicited greater baseline activity in right temporoparietal junction (RTPJ), implicated in mentalizing, or the process of making inferences about others' mental states. The lovingkindness task compared to the control task also produced marginal decreases in bias over the monthcessing, may be effective in shifting people's biases against stigmatized individuals.
We examined the feasibility and explored the physical, psychological, relational, and biological effects of Mindfulness-Based Stress Reduction (MBSR), an 8-week standardized mindfulness program, involving older married couples (60 years or older) with metabolic syndrome (one or both partners had metabolic syndrome). We also explored gender differences.

A pilot randomized controlled trial (RCT) compared MBSR to a Wait List Control (WLC) arm at baseline, post-intervention, and 3-month follow-up clinic visits. Twenty-two spouses (11 couples) self-reported stress, physical and mental functioning, mindfulness, and relationship satisfaction at each time point. Fasting glucose, cholesterol, triglycerides, blood pressure, weight, and waist circumference were measured. MBSR couples answered questions about partner influences on participation, adherence, and practice at the post-intervention visit.

In terms of adherence to MBSR sessions, four of the six couples attended all 10 sessions; one couple attended 7; and one wife attended 6 and her husband attended 5 sessions. check details In terms of efficacy, there were no significant intervention effects; however, there were significant gender by intervention effects. Pre- to post-intervention, MBSR wives displayed greater increases in physical functioning (β = 1.18,
(36) = 3.17,
= .003) and relationship satisfaction (β = .72,
(36) = 2.81,
= .007) than WLC wives. Effects for husbands were not significant. Qualitatively, participants reported encouragement and increased relationship closeness.

Engaging in MBSR as a couple to address symptoms of metabolic syndrome was well-received and feasible. Preliminary effects suggest more benefits for wives than husbands in terms of physical functioning and relational well-being.
Engaging in MBSR as a couple to address symptoms of metabolic syndrome was well-received and feasible. Preliminary effects suggest more benefits for wives than husbands in terms of physical functioning and relational well-being.
The use of mobile technology for smoking cessation holds promise for adolescents, who do not typically access traditional treatments, but most are not grounded in theory or mechanism. Operant conditioning theory suggests an addictive smoking loop is formed between nicotine use and affective states, leading to habitual cue-induced craving and automatic behavior; mindfulness training may bring automated smoking behavior into awareness, so smokers may work mindfully with cravings. Mindfulness training delivered via smartphone technology therefore has potential to help adolescent smokers break this addictive loop and quit smoking. This pair-matched cluster-randomized controlled school-based pilot study evaluated program feasibility and preliminary smoking outcomes in relation to intervention engagement.

Six high schools were pair matched and randomly assigned to one of three interventions (1) mindfulness training delivered via mobile smoking cessation application (Craving to Quit, C2Q), (2) NCI's QuitSTART smbstinence was similar between intervention conditions and tended to increase with greater engagement in each condition. Greater C2Q app engagement among continuing smokers was associated with a significantly greater decline in number of cigarettes smoked compared to the other conditions. The Craving to Quit (C2Q) mobile smoking cessation application with mindfulness training was feasible to use and has promise in assisting adolescents to quit or decrease cigarette smoking.

Developing a Smartphone App with Mindfulness Training for Teen Smoking Cessation ClinicalTrials.gov Identifier NCT02218281.
Developing a Smartphone App with Mindfulness Training for Teen Smoking Cessation ClinicalTrials.gov Identifier NCT02218281.
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