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49 ± 2.22)/<0.05 for group 1) (13.61 ± 2.02)/<0.05 for group 2) and hematocrit (HCT/L/L) (37.30 ± 7.55/<0.05 for group 1) (38.64 ± 5.42/<0.05 for group 2).
Correlating the hematological indices with the gender, age, and duration of diabetic condition will help determine future complications and the severity of the diabetic condition in type 2 DM patients.
Correlating the hematological indices with the gender, age, and duration of diabetic condition will help determine future complications and the severity of the diabetic condition in type 2 DM patients.
is among the evergreen plants native to West Africa. It is used in the management of various ailments including anemia, fever, asthma and diabetes. This study evaluated the antidiabetic and antihyperlipidemic effect of
in streptozotocin-nicotinamide-induced type 2 diabetic rats.
Type 2 diabetes mellitus was induced in overnight fasted rats with a single intraperitoneal injection of streptozotocin (60 mg/kg), followed by the administration of nicotinamide (120 mg/kg) after an interval of 15 min. Diabetic rats were orally administered with; 200, 400 and 800 mg/kg of aqueous extract of
metformin (180 mg/kg) and glibenclamide (1 mg/kg) for two weeks. The effect of treatments on fasting blood glucose, serum insulin, leptin, adiponectin, homa-ir, lipid profile, body weight, pancreatic antioxidants parameters, hepatic glycogen content, glucose-6-phosphate activity, α-amylase inhibition, α-glucosidase inhibition, lipase inhibition and histology of the organs were evaluated.
Data from this study showed that treatment with
produced a significant reduction (
0.05) in fasting blood glucose, glucose-6-phosphatase activity, serum lipase, total triglyceride, total cholesterol, low-density lipoproteins, very low-density lipoprotein, atherogenic index, coronary risk index, pancreatic α-amylase, α-glucosidase and lipase activities. Treatment with
also produced a significant (
0.05) increase in; glucose tolerance, glycogen content, leptin, adiponectin and pancreatic antioxidants (glutathione, superoxide dismutase, catalase and high-density lipoproteins). The histology of the organ showed regeneration of the pancreatic tissue after treatment with
.
This study showed that
exhibited antidiabetic and antihyperlipidemic activity in streptozotocin-nicotinamide-induced type 2 diabetic rats.
This study showed that AEPN exhibited antidiabetic and antihyperlipidemic activity in streptozotocin-nicotinamide-induced type 2 diabetic rats.
Malnutrition is a serious problem that causes high morbidity and mortality among cancer patients. There was no sufficient empirical evidence on the prevalence of malnutrition and associated factors among adult cancer hospitalized patients in Ethiopia.
This study aimed to assess the prevalence and risk factors of malnutrition among adult cancer patients receiving chemotherapy in cancer center, Ethiopia 2019.
A cross-sectional study was conducted among a sample of 281 patients selected using systematic sampling among cancer patients receiving chemotherapy. Entinostat Data were collected by patient interviews and chart reviews using a structured questioner adapted from a subjective global assessment tool. Data were analyzed by SPSS version 24.0. Descriptive statistics such as frequency distribution, mean, median, and standard deviation were used to describe characteristics. Bivariate and multivariable analyses using logistic regression models were used.
Of the 281 participating patients, 58.2% had malnutrition, which was higher among females (51.6%) than males (48.4%). The mean body mass index was 20.24 ± 3.6. Of all, 41.9% had moderate weight loss, 21.1% had severe weight loss and 52.3% had weight loss in the past two weeks. Stage four cancer (AOR = 7.2, 95% CI 1.3-38.5), loss of appetite (AOR = 4.5, 95% CI; 1.5-17.2) and diarrhea (AOR = 7.8, 95% CI 2.95-20.5) were significantly associated with malnutrition.
The prevalence of malnutrition among cancer patients who receive chemotherapy was high. Stage of cancer, appetite loss, and presence of diarrhea was found to be significant factors for malnutrition.
The prevalence of malnutrition among cancer patients who receive chemotherapy was high. Stage of cancer, appetite loss, and presence of diarrhea was found to be significant factors for malnutrition.Numerical simulations of mixed convection of Casson fluid with a heated bottom wavy wall in a trapezoidal enclosure are performed. The enclosure's left and right sidewalls are assumed to be cold temperatures, while the enclosure's bottom and top walls are kept at hot temperatures and thermally insulated, respectively. The top wall is supposed to slide at a constant speed U 0 from left to right. After transforming the governing equations into a non-dimensional form, the finite element method is employed to solve them and modeled with Comsol-Multiphysics. The effect of non-dimensional parameters such as the Richardson number ( R i = 0.1 , 1 , 10 ) , Casson fluid parameters ( ϕ = 0.1 , 0.5 , 1 ) , and the number of oscillations ( N = 0 , 1 , 2 , 3 ) on flow and thermal fields, as well as the heat transfer rate has been studied. Furthermore, the results for the Average Nusselt number over the heated bottom wavy wall under the influence of the Rayleigh number and Casson parameter are depicted. The results showed that as the Richardson number increases, so does the average Nusselt number for all Casson fluid parameter values.Glutamate plays an important role in different cellular processes. Its new applications in various industries have led to an increase in the production of it while fermentation is a very important economically method. In this study, the production of glutamate by the wild type of Corynebacterium glutamicum PTCC(Persian Type Culture Collection) 1532 was optimized using RSM. Central Composite Design (CCD) was developed by Design-Expert software version 12.0.3.0 (dx-12, State-Ease Inc.) to evaluate the effect of four important variables in five levels on glutamate production. TLC was employed to evaluate glutamate in medium qualitatively and then quantitative estimation was done by HPLC. Normal probability analysis demonstrated that data has a normal distribution. The results of ANOVA analysis showed that the urea concentration both alone and with temperature is the most effective variable in the fermentation process. Based on the quadratic model obtained in CCD, temperature 30 °C; glucose 9 g.dL-1; biotin 9 μg.
Homepage: https://www.selleckchem.com/products/ms-275.html
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