Notes

A static correction: Growth and development of a new structure-based computational simulator to be able to improve the actual obstructing effectiveness of pro-antibodies.
Short implants are used in clinical conditions of insufficient vertical bone availability. This study aimed to compare the primary stability of short implants with different macrodesigns placed in different bone densities in vitro.

One hundred twenty short (6-mm) implants (20/group) were placed at the bone level in commercially available polyurethane blocks representing type I and IV bone quality. The groups were as follows test A group (4.6-mm diameter with tapered body), test B group (4.8-mm diameter/cylindric microthreaded neck), and test C group (4.8-mm diameter, cylindric body with polished collar, three threads at the intraosseous portion). Implant primary stability was assessed using insertion torque and implant stability quotient (ISQ) values. A blinded calibrated clinician recorded all measurements. Statistical comparisons were completed using a one-way analysis of variance (ANOVA) and Bonferroni posttests.

The insertion torque values (mean ± SD) for groups A, B, and C in type I bone were 52.50 ± 5.25, 49.00 ± 5.98, and 46.25 ± 3.93, and in type IV bone, the values were 14.00 ± 2.05, 15.50 ± 2.76, and 9.75 ± 1.11, respectively. Also, the ISQ values were 67.25 ± 2.760, 69.25 ± 1.67, and 61.80 ± 5.68 (type I bone); and 53.27 ± 1.99, 60.65 ± 2.11, and 51.97 ± 4.51 (type IV bone), respectively. The comparison showed statistical differences in ISQ (Bonferroni adjusted P < .0001) for the A and B groups but also for the A and C groups (type I bone), in soft bone between the A and B groups and between the B and C groups, and also for the insertion torque values for the A and C groups and between the B and C groups in type IV bone.

Short implant macrogeometry defines primary stability. Short implants with 6-mm length and multiple threads can achieve good primary stability in vitro in type I and IV artificial bone.
Short implant macrogeometry defines primary stability. Short implants with 6-mm length and multiple threads can achieve good primary stability in vitro in type I and IV artificial bone.
To evaluate survival, complication rates, and bending moments of one- and two-piece zirconia implants restored with different abutment materials and lithium disilicate crowns after aging, compared to titanium implants restored with titanium base-supported lithium disilicate crowns.

Sixty anterior crowns were either screwretained on two-piece titanium implants (C) and two-piece zirconia implants (T1, T2, T3) or cemented on one-piece zirconia implants (T4), resulting in 5 groups with 12 specimens each. For the screw-retained crowns, different abutment materials and implant connections were tested titanium base with internal conical connection and horizontal joint component (C and T2), zirconia with internal hexagonal connection and horizontal joint component (T1), and polyetherketoneketone with internal hexagonal connection and horizontal joint component (T3). After artificial aging with thermocycling (5°C to 50°C) and chewing simulation (1,200,000 cycles, 49 N, 1.67 Hz), the surviving specimens were loadedr aging, yet the number of technical complications was high. New prosthetic solutions, such as titanium bases or polyetherketoneketone abutments, may offer a comparable treatment option to restore two-piece zirconia implants.
The zirconia one- and two-piece implants presented high survival rates after aging, yet the number of technical complications was high. New prosthetic solutions, such as titanium bases or polyetherketoneketone abutments, may offer a comparable treatment option to restore two-piece zirconia implants.
To evaluate the influence of low-dose protocols, with different numbers of basis images, on the precision of linear bone measurements in CBCT images.

Five polyurethane mandibles, with different levels of bone resorption, were used in this in vitro study. To obtain the reference standard, landmarks were made in the mandibular superior and buccal cortices, and then a digital caliper was used to measure the bone height and thickness at these regions. CBCT images were obtained with the PaX-i3D (Vatech) unit set at 50 kV, 4 mA, 0.2-mm voxel size and 50 × 50-mm field of view. Keeping these parameters fixed, each mandible was scanned twice, with different protocols Low dose (L) had an acquisition time of 24 seconds and 720 basis images, and ultralow dose (UL) had an acquisition time of 15 seconds and 450 basis images. Then, measurements of bone height and thickness were performed on the images, using the previously determined landmarks as reference. Selleckchem PF-573228 The obtained data were submitted to statistical analysis, with a significance level of .05. Analysis of variance, Student t test, and intraclass correlation coefficient were employed.

Regarding bone height, there were no significant differences between the measurements obtained with the L and UL protocols (P = .8648). Additionally, the L and UL protocols did not differ in relation to the reference standard (P = .8717 and P = .9928, respectively). Likewise, there were no significant differences between the measurements obtained with the L and UL protocols (P = .7969) for bone thickness, nor between these protocols and the gold standard (P = .7455).

Considering the great demand for precise measurements in implantology, protocols of low-dose radiation can be used without compromising clinical planning.
Considering the great demand for precise measurements in implantology, protocols of low-dose radiation can be used without compromising clinical planning.
The aim of this study was to explore the influence of different bone grafts, demineralized freeze-dried bone allograft (DFDBA, OraGraft), and deproteinized bovine bone mineral (DBBM, Bio-Oss) implanted in mouse calvaria defects on gene expression.

Male C57BL/6MLac mice were separated into three groups as follows group 1-defect without graft as control, group 2-DFDBA, and group 3-DBBM. Affymetrix DNA microarrays were used to characterize gene expression in bone after 3 months of graft healing. Differential expression of designated genes discovered by microarray analysis was confirmed using real-time polymerase chain reaction (PCR) and immunohistochemistry.

Compared with normal bone healing, 355 and 1,108 coding genes of bone grafted with DFDBA were upregulated and downregulated, respectively. The upregulated genes were mainly involved in chemokine signaling, macrophage activity, osteoclast activity, cytokine expression, T-cell receptor signaling, apoptosis, and MAPK signaling. The downregulated genes were predominantly involved in calcium regulation in cardiac cells, chemokine signaling, MAPK signaling, and adipogenesis.
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