Notes

Characteristics associated with dipole in a fixed non-homogeneous electro-magnetic discipline.
Topical candidiasis is a known skin fungal infection which is usually treated by conventional dosage forms such as cream, gel, emulgel which are having numerous adverse effects on skin. To overcome such disadvantages, different novel drug delivery systems have been considered. Polymer based nano-particulate systems have shown good skin penetration after topical application. Therefore, in the present study the main focus was on the pathology, pathogenesis, and consequently topical treatment of candidiasis. Nanogel containing miconazole have been prepared from the natural polymers i.e. gelatin and chitosan. The nanogel of miconazole (100 mg) nitrate was formulated by modified emulsification-diffusion technique and characterized for different parameters. From all the seven nanogel formulations named as F1 to F7, F1 (Gelatin and Chitosan in the percentage of 82.85 and 17.15 respectively) have been selected as model formulations. The reason behind that was as per ICH stability guideline, the formulations F1 was found optimum and stable. Miconazole nanogel formulations F1 also showed the maximum release i.e. 78 % approximately. XRD showed the formulated nanogel was in crystalline shape. In summary, the miconazole nanogel drug delivery systems have two main advantages i.e. they are topical preparation as well as nano sized. It can be postulated that nanogel may be a best approach to treat the fungal skin diseases.This study was designed to investigate the wound healing effects of a Traditional Chinese Medicine (Longxuejie) combined with dragon's blood capsule. A total of 80 patients with ulcerative bedsore observed in our hospital department of Geriatrics were selected from May 2016 to May 2017. They were randomly divided into control group received Longxuejie capsules and study group received new wound dressing combined with Longxuejie, 40 cases in each group. Clinical efficacy and degree of pain were observed and compared in patients. The total effective rate was 95.00% in study group and 85.00% in control group (P0.05). The difference was statistically significant after treatment (P less then 0.05). New wound dressing combined with dragon blood capsule in the treatment of bedsore in the elderly ulcers can achieve ideal clinical efficacy and effective relieve the pain degree of patients, which can be used as the preferred treatment program.The objective of this study is to observe and analyze the efficacy of calcium hydroxide and chlorhexidine in pulp revascularization after trauma in young permanent teeth. selleck products A total of 120 patients who were treated in our hospital for pulp revascularization after trauma in young permanent teeth were enrolled as research objects in the study. The patients were treated with calcium hydroxide and chlorhexidine and the overall treatment efficiency was statistically observed. The improvement in various indicators before and after treatment was observed, including pain symptom score, gum swelling symptom score, tooth looseness score. The overall treatment efficiency was recorded. The results showed that there were 70 cases of significant effective treatment, 42 cases of effective treatment, and 8 cases of ineffective treatment, respectively, with overall treatment efficiency of 93.33%. Compared with the pain score, gum swelling score and teeth looseness score before treatment, these indicators showed a significant improvement after treatment, p less then 0.05. The application of calcium hydroxide and chlorhexidine during pulp revascularization after trauma in young permanent teeth can significantly improve the therapeutic effect and achieve higher therapeutic efficiency, demonstrating huge application value.The aim of this study is to observe and analyze the clinical efficacy of simvastatin combined with exercise training in the treatment of stationary chronic obstructive pulmonary disease complicated with metabolic syndrome. In this study, 180 patients who had been treated for stable chronic obstructive pulmonary disease (COPD) complicated with metabolic syndrome in our hospital were enrolled as research objects. The selected patients were randomly divided into research group receiving simvastatin combined with exercise training and control group accepting routine therapy, each containing 90 cases. The therapeutic effects of the two groups were compared. The CAT score, insulin resistance index and 6 min walking distance of the two groups were compared. The results showed that compared with the control group, the improvement effect of the research group was more obvious, and the effect was better than that of the control group, p less then 0.05. The levels of IL-6 (interleukin-6), IL-8 (interleukin-8) and other inflammatory factors were significantly lower in the research group than those in the control group, p less then 0.05. Simvastatin combined with exercise training in the treatment of stationary chronic obstructive pulmonary disease with metabolic syndrome is an effective treatment, which can significantly improve the treatment effect and help patients to achieve a higher quality of life.This clinical observation aims to observe and analyze the effect of Yaotongning capsule in the treatment of lumbar disc herniation, and provide valuable guidance for clinical practice. A total of 120 patients who confirmed with lumbar disc herniation in our hospital from January 2016 to December 2018 were enrolled as research objects in this study. On the other hand, another 120 patients who were treated for lumbar disc herniation in our hospital during the same period were classified in the control group. General routine treatment mode was adopted for the control group, while Yaotongning capsule was given to the study group on the basis of general routine treatment. The therapeutic effect was observed and compared between the two groups. The overall treatment efficiency, VAS score, serum cytokine levels and quality of life were compared between the two groups. The results showed the study group exhibited significant improvement compared with control group, p less then 0.05. The application of Yaotongning capsule can achieve markedly good results in treatment of lumbar disc herniation, which is worthy of popularization and application.
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