Notes

Occurrence from the 7 most common serotypes involving Shiga toxin-producing Escherichia coli in meat reduces stated in meat-processing plants in the condition of São Paulo, South america.
The suitability of multication doping to stabilize the disordered Fd3̅m structure in a spinel is reported here. In this work, LiNi0.3Cu0.1Fe0.2Mn1.4O4 was synthesized via a sol-gel route at a calcination temperature of 850 °C. LiNi0.3Cu0.1Fe0.2Mn1.4O4 is evaluated as positive electrode material in a voltage range between 3.5 and 5.3 V (vs Li+/Li) with an initial specific discharge capacity of 126 mAh g-1 at a rate of C/2. This material shows good cycling stability with a capacity retention of 89% after 200 cycles and an excellent rate capability with the discharge capacity reaching 78 mAh g-1 at a rate of 20C. In operando X-ray diffraction (XRD) measurements with a laboratory X-ray source between 3.5 and 5.3 V at a rate of C/10 reveal that the (de)lithiation occurs via a solid-solution mechanism where a local variation of lithium content is observed. A simplified estimation based on the in operando XRD analysis suggests that around 17-31 mAh g-1 of discharge capacity in the first cycle is used for a reductive parasitic reaction, hindering a full lithiation of the positive electrode at the end of the first discharge.One of the techniques to increase oil recovery from hydrocarbon reservoirs is the injection of low salinity water. It is shown that the injection of low salinity water changes the wettability of the rock. However, there are argumentative debates concerning low salinity water effect on changing the wettability of the oil/brine/rock system in the oil reservoirs. In this regard, molecular dynamics simulation (MDS) as a tool to simulate the phenomena at the molecular level has been used for more than a decade. In this study, the Zisman plot (presented by KRUSS Company) was simulated through MDS, and then, contact angle experiments for n-decane interactions on the Bentheimer substrate in the presence of different concentrations of sodium ions were conducted. MDS was then used to simulate experiments and understand the wettability trend based on free-energy calculations. Hereafter, a new model was developed in this study to correlate free energies with contact angles. The developed model predicted the experimental results with high accuracy (R2 ∼ 0.98). A direct relation was observed between free energy and water contact angle. In contrast, an inverse relation was noticed between the ion concentration and the contact angle such that an increase in the ion concentration resulted in a decrease in the contact angle and vice versa. In other terms, increasing brine ionic concentrations in the presence of n-decane is linked to a decrease in free energies and an increase in the wetting state of a sandstone. The comparison between the developed model's predicted contact angles and experimental observations showed a maximum deviation of 14.32%, which is in satisfactory agreement to conclude that MDS can be used as a valuable and economical tool to understand the wettability alteration process.Antimicrobial peptides are a potential solution to the threat of multidrug-resistant bacterial pathogens. Recently, deep generative models including generative adversarial networks (GANs) have been shown to be capable of designing new antimicrobial peptides. Intuitively, a GAN controls the probability distribution of generated sequences to cover active peptides as much as possible. This paper presents a peptide-specialized model called PepGAN that takes the balance between covering active peptides and dodging nonactive peptides. As a result, PepGAN has superior statistical fidelity with respect to physicochemical descriptors including charge, hydrophobicity, and weight. Top six peptides were synthesized, and one of them was confirmed to be highly antimicrobial. The minimum inhibitory concentration was 3.1 μg/mL, indicating that the peptide is twice as strong as ampicillin.The tumor microenvironment (TME) plays a significant role in weakening the effect of cancer immunotherapy, which calls for the remodeling of TME. Herein, we fabricated a nanostructured lipid carrier (NLC) to codeliver doxorubicin (Dox) and sorafenib (Sfn) as a drug delivery system (NLC/D-S). The Sfn was expected to regulate the TME of esophagus cancer. As a result, the immune response induced by Dox-related immunogenicity cell death could be fully realized. Our results demonstrated that Sfn was able to remodel the TME through downregulation of regulatory T cells (Treg), activation of effector T cells, and relieving of PD-1 expression, which achieved synergistic effect on the inhibition of primary tumor but also subsequent strong immune response on the regeneration of distant tumor.Three types of multiwalled carbon nanotubes (MWCNTs, MWCNTs-OH, and MWCNTs-COOH) were used as carriers and five types of ionic liquids (ILs) were immobilized on each carrier by an impregnation method. Boehm titration, Fourier-transform infrared spectroscopy, X-ray photoelectron spectroscopy, specific surface area analysis by the Brunauer-Emmett-Teller method, and thermogravimetric analysis were performed to investigate [C4mim]HSO4 adsorption by the MWCNTs. The MWCNT-immobilized IL was used for Cr(VI) removal from a water phase. The adsorption properties of MWCNTs-COOH-immobilized [C4mim]HSO4 were investigated by single-factor analysis. The results showed that the Cr(VI) removal rate was 52.14% and the adsorption capacity was 31.29 mg/g. The optimum adsorption conditions were as follows initial Cr(VI) concentration, 60 mg/L; adsorbent dosage, 50 mg; pH 2.0; adsorption temperature 40 °C; and adsorption time, 200 min. Adsorption isotherm data fitted the Freundlich model, which indicates that the adsorption process was in line with the multimolecular layer adsorption theory. The Cr(VI) adsorption behaviors of the three adsorbents were consistent with a pseudo-second-order dynamic model. Thermodynamic analysis of the reaction systems was also performed. The Cr(VI) removal rates of MWCNTs-3, MWCNTs-OH-3, and MWCNTs-COOH-3 were 27.97, 9.39, and 7.34% lower than the initial removal rates after five cycles.In the current context, the development of bio-based and high-performance materials is one of the main research priorities. This study aims to combine the outstanding properties of cellulose nanofibrils (CNFs) or nanocrystals (CNCs) with those of bio-based poly(lactic acid) (PLA). Three-phase multilayered materials (TMLs) were built up by complexing a dry CNF- or CNC-based film with two PLA sheets, using a heat-pressing process. Before the preparation of the nanocellulosic films, CNFs and CNCs were modified by the adsorption of a rosin-based nanoemulsion. The rosin mixture as a natural compound is of interest because of its low cost, renewability, hydrophobicity, and its antimicrobial and antioxidant properties. Lorlatinib inhibitor After demonstrating the efficiency of the complexing procedure, we investigated the barrier properties of the multilayered materials against both oxygen and water vapor, with highly encouraging results. In fact, the presence of nanocellulose as an inner layer between the two PLA films significantly enhanced the oxygen barrier, with a decrease in oxygen permeability comprised between 84 and 96% and between 44 and 50% for neat nanocelluloses and nanocelluloses with rosins as the inner layer, respectively.
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