Notes

Primary statement along with treatment of hot electrons from room temperature.
Santa Ana winds (SAWs) are associated with anomalous temperatures in coastal Southern California (SoCal). As dry air flows over SoCal's coastal ranges on its way from the elevated Great Basin down to sea level, all SAWs warm adiabatically. Many but not all SAWs produce coastal heat events. The strongest regionally averaged SAWs tend to be cold. In fact, some of the hottest and coldest observed temperatures in coastal SoCal are linked to SAWs. We show that hot and cold SAWs are produced by distinct synoptic dynamics. High-amplitude anticyclonic flow around a blocking high pressure aloft anchored at the California coast produces hot SAWs. Cold SAWs result from anticyclonic Rossby wave breaking over the northwestern U.S. Hot SAWs are preceded by warming in the Great Basin and dry conditions across the Southwestern U.S. Precipitation over the Southwest, including SoCal, and snow accumulation in the Great Basin usually precede cold SAWs. Both SAW flavors, but especially the hot SAWs, yield low relative humidity at the coast. Although cold SAWs tend to be associated with the strongest winds, hot SAWs tend to last longer and preferentially favor wildfire growth. Historically, out of large (> 100 acres) SAW-spread wildfires, 90% were associated with hot SAWs, accounting for 95% of burned area. As health impacts of SAW-driven coastal fall, winter and spring heat waves and impacts of smoke from wildfires have been recently identified, our results have implications for designing early warning systems. The long-term warming trend in coastal temperatures associated with SAWs is focused on January-March, when hot and cold SAW frequency and temperature intensity have been increasing and decreasing, respectively, over our 71-year record.
The online version contains supplementary material available at 10.1007/s00382-021-05802-z.
The online version contains supplementary material available at 10.1007/s00382-021-05802-z.There is a need for valves and pumps that operate at the microscale with precision and accuracy, are versatile in their application, and are easily fabricated. To that end, we developed a new rotary planar multiport valve to faithfully select solutions (contamination = 5.22 ± 0.06 ppb) and a rotary planar peristaltic pump to precisely control fluid delivery (flow rate = 2.4 ± 1.7 to 890 ± 77 μL/min). Both the valve and pump were implemented in a planar format amenable to single-layer soft lithographic fabrication. These planar microfluidics were actuated by a rotary motor controlled remotely by custom software. Eribulin cell line Together, these two devices constitute an innovative microformulator that was used to prepare precise, high-fidelity mixtures of up to five solutions (deviation from prescribed mixture = ±|0.02 ± 0.02| %). This system weighed less than a kilogram, occupied around 500 cm3, and generated pressures of 255 ± 47 kPa. This microformulator was then combined with an electrochemical sensor creating a microclinical analyzer (μCA) for detecting glutamate in real time. Using the chamber of the μCA as an in-line bioreactor, we compared glutamate homeostasis in human astrocytes differentiated from human-induced pluripotent stem cells (hiPSCs) from a control subject (CC-3) and a Tuberous Sclerosis Complex (TSC) patient carrying a pathogenic TSC2 mutation. When challenged with glutamate, TSC astrocytes took up less glutamate than control cells. These data validate the analytical power of the μCA and the utility of the microformulator by leveraging it to assess disease-related alterations in cellular homeostasis.Healthcare is becoming increasingly automated with the development and deployment of care robots. There are many benefits to care robots but they also pose many challenging ethical issues. This paper takes care robots for the elderly as the subject of analysis, building on previous literature in the domain of the ethics and design of care robots. Using the value sensitive design (VSD) approach to technology design, this paper extends its application to care robots by integrating the values of care, values that are specific to AI, and higher-scale values such as the United Nations Sustainable Development Goals (SDGs). The ethical issues specific to care robots for the elderly are discussed at length alongside examples of specific design requirements that work to ameliorate these ethical concerns.While instruments to price congestion exist since the 1970s, less than a dozen cities around the world have a cordon or zone pricing scheme. Geneva, Switzerland, may be soon joining them. This paper builds on a detailed review of the existing schemes to identify a set of plausible design options for the Geneva congestion charge. In turn, it analyzes their acceptability, leveraging a large survey of residents of both Geneva and the surrounding areas of Switzerland and France. Our original approach combines a discrete choice experiment with randomized informational treatments. We consider an extensive set of attributes, such as perimeter, price and price modulation, use of revenues, and exemption levels and beneficiaries. The informational treatments address potential biased beliefs concerning the charge's expected effects on congestion and pollution. We find that public support depends crucially on the policy design. We identify an important demand for exemptions, which, albeit frequently used in the design of environmental taxation, is underexplored in the analysis of public support. This demand for exemptions is not motivated by efficiency reasons. It comes mostly by local residents, for local residents. Further, people show a marked preference for constant prices, even if efficiency would point to dynamic pricing based on external costs. Hence, we highlight a clear trade-off between efficiency and acceptability. However, we also show, causally, that this gap can in part be closed, with information provision. Analyzing heterogeneity, we show that preferences vary substantially with where people live and how they commute. Even so, we identify several designs that reach majority support.
The COVID-19 crisis generated changes in consumer behavior related to food purchase and the management of food packaging. Due to the intensification of online purchases for home delivery, there has been an increase in the use of food packaging (mostly non-biodegradable or non-renewable). Moreover, the fear of contamination with SARS-CoV-2 through contact with materials and surfaces has led to an intensified disposal of food packaging, promoting a setback in waste management.

The purpose of this short commentary is to address the impacts of increased use and disposal of food packaging during the COVID-19 pandemic. Technological solutions have been presented as tools to minimize the environmental impacts of the increased volume of disposed food packaging (namely, the development of biodegradable food packaging) as well as to minimize the occurrence of cross-contamination (namely, the incorporation of active antiviral components).

The consumer behavior in the COVID-19 pandemic requires actions concerning adoption of bioplastics for single-use food packaging.
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