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Evaluation of the particular effectiveness, protection, and also stability regarding posterior holding chamber phakic intraocular lens with regard to repairing intractable myopic anisometropic amblyopia within a child cohort.
A 52-year-old woman presented with fever and a persisting calf abscess ten years after she had received an aorta-bifemoral bypass. Her infection parameters were increased and she had anaemia. CT of the abdomen revealed air surrounding the proximal anastomosis of the bypass suggesting bypass graft infection. The diagnosis of an aorta-duodenal fistula was confirmed by gastroduodenoscopy showing migration of the bypass through the wall of the duodenum into the intestinal lumen. The bypass was resected and reconstructed using the superficial femoral vein. The patient recovered uneventful.OBJECTIVE Consultations between general practitioners (GPs) and hospital specialists are traditionally conducted by phone. A conversation by phone where a GP seeks advice regarding a patient, who is unknown to the specialist, can have limitations. An e-consultation service for internal medicine allows GPs to consult an internal medicine specialist for clinical queries. In this study we evaluated GP use of internal medicine e-consultations. DESIGN Observational study. METHOD Eligible patients were all those for whom the GP used an internal medicine e-consultation, provided by Zuyderland Medical Centre, location Sittard-Geleen, the Netherlands, in the period 2017-2018. Data on patient demographics, content of the GP clinical query, and any preceding diagnostics were collated. Furthermore, the internal medicine specialist response was categorised, including the presence of any patient referral advice. RESULTS 136 (88.6%) of all 154 GPs in the region used an e-consultation at least once, and the clinical queries covered all areas of internal medicine. A total of 1047 eligible patients were discussed by GPs in an e-consultation; 19.6% of them attended the internal medicine out-patient clinic within three months of the index episode. The use of e-consultations by GPs led to a 70% reduction in referrals when compared to the situation where e-consultations were not available. CONCLUSION GPs used internal medicine e-consultations for a wide range of questions covering all areas of internal medicine. In more than 80% of cases, the GP continued to manage the patient, resulting in a reduction of the actual number of patient referrals to the internal medicine out-patient clinic.A 6-year-old boy, known with Potocki-Lupski syndrome (17p11.2 duplication), mild intellectual disability and constipation, presented with episodes of abdominal pain. His defecation pattern was normal with polyethylene glycol. Physical examination showed a hypertympanic distended abdomen. Extreme dilatation and elongation of the colon was seen on abdominal x-ray, corresponding with aerophagia.BACKGROUND Vertigo is a common complaint and may rarely be the presenting symptom of a paraneoplastic neurological syndrome (PNS). CASE DESCRIPTION A 76-year-old woman presented at the ER with subacute cerebellar syndrome and severe vertigo. Laboratory testing revealed mild anaemia. A cerebral CT scan showed no intracranial pathology. The patient was admitted for observation. History-taking revealed she been suffering from general malaise and had unintentionally lost 16 kg in weight over recent months. Camostat chemical structure Further PET-CT investigations revealed multiple enlarged mediastinal and abdominal lymph nodes with high metabolic activity. Histopathological investigation of a lymph node biopsy showed a malignancy originating from the genital tract. Positive anti-neuronal antibodies (anti-Yo) and an elevated CA-125 concentration were found in peripheral blood. We diagnosed paraneoplastic cerebellar degeneration as the first manifestation of hitherto undiagnosed occult ovarian cancer. CONCLUSION In a patient with subacute, cerebellar syndrome with severe vertigo, after ruling out other causes, the diagnosis of PNS should be considered. Determination of anti-neuronal antibodies can help in the diagnosis. Early recognition of PNS is important for the diagnosis and treatment of the underlying malignancy.Patients with metastatic prostate cancer are living longer than they used to, thanks to a wider range of therapeutic options. This means that an increasing number of men will receive long-term treatment with anti-hormonal therapy - androgen-deprivation therapy (ADT) - and the risk of side effects from this therapy is increasing. A relevant decrease in bone density is increasingly seen in patients receiving ADT, which means that a disproportionate increase in risk of fractures is seen in aging patients. Urologists are confronted with these patients in clinical practice. The question is how urologist-care for these patients is organised in the Netherlands. A survey among urologists in the Netherlands revealed that there is great diversity in how they think and act, and that there is a need for national guidelines and additional training on this subject.A lot of research has been conducted into night work in recent years. This shows that people who work nights have an increased risk of type 2 diabetes and cardiovascular disease; people doing night work in the healthcare sector also have an increased risk of influenza and respiratory tract infections. There are also differences in sleep patterns, physical activity and diet between those who work at night and those who work during the day. However, at this point in time there are no effective lifestyle interventions available to lower the risks associated with night work. Along with the Health Council of the Netherlands we advise limiting night work as much as possible. Work is currently in progress on occupational medicine guidelines for night work.Dyspnoea is an important and common symptom in patients with pulmonary or cardiovascular disease. It is a vital signal that we all can experience, for instance during heavy exercise, but it can also be an expression of a variety of diseases. In this educational article, we provide an answer to 10 questions on the causes of dyspnoea and the effectiveness of various diagnostic and therapeutic strategies. We propose a strategy to assess dyspnoea in clinical practice. Key points are determining the severity of the problem, forming a differential diagnosis, thinking about the mechanism of dyspnoea and intervening in a timely manner. We conclude that the assessment and treatment of dyspnoea often requires a multidisciplinary approach.
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