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Expectant mothers adiponectin helps prevent visceral adiposity and adipocyte hypertrophy within pre-natal androgenized feminine these animals.
Our goal was to examine the relationship between age and engine displacement in cubic centimeters (CCs) and crash responsibility.

Male motorcyclists, aged 16-94, involved in a fatal crash in the United States (1987-2015) who tested negative for both drugs and alcohol were included. Employing a case control design, cases had committed one or more Unsafe Motorcyclist Actions (UMAs), the proxy measure of responsibility; controls had no UMAs recorded. Odds ratios were computed via multinomial regression examining the effect of motorcyclists' age and motorcycle displacement (up to 1500 CCs, in 250 CC increments) on crash responsibility by any UMA and top three individual UMAs committed.

A total of 19,166 motorcyclists met our inclusion criteria. Increased displacement was observed in older motorcyclists and in more recent crashes. Fifty-six percent of motorcyclists committed one or more UMAs (n = 10,743). The top three individual UMAs were Speeding (35%, n = 6,728), Weaving (24%, n = 3,269), and Erratic Operlp to curb the trend seen between high-powered motorcycles and crash responsibility.
Education and legislative measures should be considered. Educationally, the development of training interventions focusing on control, stability, and breaking differences with more powerful motorcycles (750 to 1250 CCs) is needed. Legislatively, licensing tiers could be employed based on displacement and educational requirements. Education and legislative measures could help to curb the trend seen between high-powered motorcycles and crash responsibility.
Due to their size and weight, trucks require more space and time to make left turns when exiting or entering a roadway. Therefore, appropriate median treatments are critical for roadways with substantial truck traffic. The two-way left-turn lane (TWLTL) and raised median (RM) are the two types of median most commonly used to improve roadway mobility and manage roadway accessibility. However, previous studies on these median treatments have focused primarily on the general traffic conditions and geometric roadway features without considering the truck traffic impact.

To fill this gap, this study investigates the truck impacts on TWLTL and RM by considering two major influencing factors - truck percentage and roadway access point density. First, a negative binomial regression is developed to analyze the relationship between crash frequency and various influencing factors. Next, the crash rate difference analysis between the TWLTL and RM is conducted to identify critical points for these two factors.

The findings indicate that, compared with RM, TWLTL has significantly higher crash frequency, especially for roadways with a higher percentage of trucks. This suggests that the percentage of trucks should be taken into consideration when selecting an appropriate type of roadway median.
The findings indicate that, compared with RM, TWLTL has significantly higher crash frequency, especially for roadways with a higher percentage of trucks. This suggests that the percentage of trucks should be taken into consideration when selecting an appropriate type of roadway median.
Graduated driver licensing (GDL) systems have been shown to reduce rates of crashes, injuries, and deaths of young novice drivers. However, approximately one in three new drivers in the United States obtain their first driver's license at age 18 or older, and thus are exempt from most or all provisions of GDL in most states.

In July 2015, the state of Indiana updated its GDL program, extending its restrictions on driving at night and on carrying passengers during the first 6 months of independent driving, previously only applicable to new drivers younger than 18, to all newly-licensed drivers younger than 21 years of age. The current study examined monthly rates of crashes per licensed driver under the affected conditions (driving at night and driving with passengers) among Indiana drivers first licensed at ages 18, 19, and 20 under the updated GDL system compared with drivers licensed at the same ages under the previous GDL system. We used Poisson regression to estimate the association between the GDL syg drivers licensed under the updated GDL system. This mirrored a statewide increase in crash rates among drivers of all ages over the study period and likely reflected increased overall driving exposure. The proportions of all crashes that were at night or with passengers did not change. Practical Applications More research is needed to understand how older novice drivers respond when GDL systems originally designed for younger novice drivers are applied to them.
More than 800 pedestrians die annually in crashes on interstates and other freeways in the United States, but few studies have examined their characteristics.

Data from the Fatality Analysis Reporting System on pedestrians fatally injured during 2015-2017 were analyzed. Chi-square tests compared characteristics of pedestrians killed on interstates and other freeways with those that died on other roads, and across crash types among freeway deaths. Land use characteristics of locations where pedestrians were killed while crossing freeways in a large state (California) were identified using Google Earth.

A larger proportion of pedestrians killed on freeways died on dark and unlit roads (48% vs. GLPG0187 32%), were male (78% vs. 68%), or were ages 20-44 (55% vs. 32%) compared with pedestrians killed on other roads. Crossing (42%) was the most common crash type among pedestrian deaths on freeways, followed by disabled-vehicle-related crashes (18%). Pedestrians who died while crossing more often had blood alcohol conclp.
A surprising proportion of pedestrian deaths occur on controlled-access roads not designed for walking. Countermeasures for these crashes need to be implemented to see meaningful reductions in pedestrian fatalities overall. Practical applications Improving roadway and vehicle lighting, requiring reflective warning devices for marking disabled vehicles, constructing pedestrian overpasses and underpasses in areas frequently crossed, and promoting alternative means of traveling between residential and commercial areas could help.
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