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Clinical characteristics and also procedure associated with hard working liver injuries throughout patients along with gentle or even moderate coronavirus ailment 2019.
BACKGROUND AND AIM All human beings have the need to feel connected with others. However, researchers have found that for those aged 80+, loneliness markedly increases and that such loneliness is often linked to life changes or the loss of a close relative. The loss of a life partner is considered to have a greater impact on men's identify, social engagement and management of life. The aim of this study was to deepen understanding of older (80+) men's life after the loss of their life partners. THEORETICAL FRAMEWORK Caring science and Eriksson's theory of caritative caring form the theoretical base for the study and its interpretative framework. The central concepts are suffering of life and desire of life. INFORMANTS, METHODOLOGY AND METHODS A total of five men aged 81-91 gave thereby consent for participation in the study. Emanating from hermeneutical methodology, qualitative deep interviews with a narrative approach were used to collect data. Thereafter, a six-step qualitative thematic analysis in accordance with Braun and Clarke was used to analyse the text. INTERPRETATION AND CONCLUSION Four themes emerged reconciliation with one's lived life, living in the present with uncertainty about the future, a reorientation in life including new living conditions and living with the hope of finding a new life partner and feeling loved. We found that loss can lead to suffering in life. The life can be filled with loneliness, emptiness, life weariness and an absence of desire, hope and longing. Yet there is a vitality in suffering that enables to find new meaning contexts and desire for life. Here, the fundamental choice underpinning the movement between life suffering and desire for life is comprised of reconciliation with one's lived life, living in the present, daily habits and routines, being seen, participation, love and thoughtfulness. © 2020 The Authors. Scandinavian Journal of Caring Sciences published by John Wiley & Sons Ltd on behalf of Nordic College of Caring Science.BACKGROUND AND AIMS The optimal valve and prosthesis in patients with aortic valve infective endocarditis with annular abscess is controversial. If extensive annular defects occur after debridement, standard techniques are difficult; more complex aortic root replacement (ARR) or aortic valve translocation technique are inevitable. The Solo Smart stentless bioprosthesis is specially designed for supra-annular implantation without annular stitches. METHODS Nineteen patients with active aortic valve infective endocarditis underwent aortic valve replacement in the past 3 years. Of these, we performed aortic valve replacement using the Solo Smart valve in four patients with extensive annular destruction and complex aortic root pathologies requiring reconstruction. RESULTS Although more than two-thirds of the annular structure was missing after radical debridement of infected tissues, supra-annular aortic valve replacement with the Solo Smart valve could be performed successfully in all four patients. All patients are doing well without prosthetic valve dysfunction and/or recurrent infection. CONCLUSION The supra-annular aortic valve replacement using the Solo Smart valve is considered to be a useful alternative to standard aortic valve replacement in patients complicated with extensive annular defect. It is a simple and technically less demanding alternative to ARR or aortic valve translocation technique. © 2020 Wiley Periodicals, Inc.OBJECTIVE Improved treatment outcome in family-based treatment (FBT) for anorexia nervosa (AN) is predicted by weight gain occurring early in the course of treatment (i.e., about 4 lbs by week 4). Although prior work suggests that early weight gain in higher levels of care (e.g., partial hospitalization programs [PHP]) predicts weight restoration at discharge, no study has examined the specific rate of gain within FBT-informed PHP programs that best predicts treatment response. METHOD This study examined rate of weight gain in pounds and percent expected body weight (EBW) that predicts positive outcome in 70 patients (M age = 15.49 years, SD = 2.56) with AN who were enrolled in a family-based PHP. RESULTS Receiver operator characteristic analyses demonstrated that changes in %EBW during weeks 2-5 were more useful than changes in weight in predicting positive outcome. Gaining at least 8.9 pounds or over 8% of EBW in the first 4 weeks of treatment significantly predicted positive outcome. DISCUSSION Findings suggest that positive outcome in an FBT-informed PHP is predicted by rapid weight gain in the initial weeks of treatment. Research is needed to identify specific family and patient characteristics that facilitate weight gain and to develop corresponding interventions to improve outcome. © 2020 Wiley Periodicals, Inc.BACKGROUND AND AIM Over the past years, three-dimensional (3D) models of patient-specific anatomical conditions are being used to improve the comprehension and surgical management of a variety of diseases. It is an additional diagnostic tool that aids clinical decision-making. Furthermore, this technology is still not routinely used in the medical field since its availability is limited by cost and complex process. METHODS AND RESULTS We describe a patient with a balanced-type double aortic arch encircling trachea and esophagus. Considering the clinical symptoms, surgical decompression of these structures and defined aortic arch reconstruction was indicated. Voxtalisib The 3D printed model revealed narrowing of the left aortic arch at the junction of the descending thoracic aorta that did not clearly appear on the conventional images reconstruction. The left aortic arch was divided and the symptoms completely disappeared. No immediate or late complications occurred. CONCLUSION 3D printed models can be helpful in surgical planning of congenital heart malformations. It should be strongly considered as an additional tool in complex cases. © 2020 Wiley Periodicals, Inc.Metallophilic macrophages (MMs) are a distinct cell type of the rodent thymus. Our previous research has focused on the morphological characteristics of MMs, as well as on the molecular mechanisms involved in the development and tissue positioning of these cells. However, the postnatal development of MMs has not been sufficiently studied. In the present study, we investigated the positioning of MMs in the rat thymus between postnatal day 0 (P0) and P30. On P0, MMs were evenly distributed all over the thymic tissue-that is, the cortex, cortico-medullary zone and medulla. From P0 to P15, the number of MMs in the thymic cortex significantly decreased, and after P15, this number did not change. Thus, the present study shows that on P15, MMs almost completely disappear from the thymic cortex and show their adult position in the cortico-medullary zone and in the medulla. © 2020 Blackwell Verlag GmbH.
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