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Outside of Caloric intake, Short-term Alternate-day Fasting Reduces NASH, Using Modulation involving Indicators involving Lipogenesis, Autophagy, Apoptosis, and Infection inside Rats.
Thiel-embalmed cadavers are a valuable resource for physical examination education. (Journal of Surgical Orthopaedic Advances 30(2)112-115, 2021).Orthopaedic surgeons are frequently required to make estimations, often without the use of measuring tools, including the lengths of wounds, incisions, bone fragments, and soft tissue defects. To evaluate the accuracy of these estimations, simulated wounds of randomized lengths were drawn on a healthy volunteer. Cefodizime cost Resident and attending physicians estimated the length of each wound via digital photograph and subsequently in person. Comparison of digital photograph versus in-person estimation was completed with paired t-test. The accuracy of estimation by experience level was assessed using Spearman rank. Accuracy was higher with in-person measurement compared with digital photographs, but overall low in both settings. There was no correlation between better accuracy and more experience in either setting. In order to properly guide treatment decisions and document physical exam findings, a ruler should be used rather than visual estimation alone. Likewise, clinical photographs used for patient care should always include a ruler. (Journal of Surgical Orthopaedic Advances 30(2)108-111, 2021).This study evaluates the efficacy of North Carolina's Strengthen Opioid Misuse Prevention (STOP) Act in reducing the volume and rate of 90-day perioperative opioid prescribing to patients ages 18 and older after orthopaedic trauma surgery. Patients undergoing fracture surgery from January 2017 to June 2017 (pre-STOP) were compared with patients undergoing fracture surgery from January 2018 to June 2018 (post-STOP). Adjusted analyses demonstrated that patients undergoing surgery after the STOP Act (n = 730) were prescribed significantly lower volume of opioids in the discharge to 2-week time frame and at the first postoperative prescription (7.3 and 5.8 fewer oxycodone, respectively). Otherwise, there were no significant differences between the two cohorts in adjusted volume or rates of 90-day opioid prescribing. The STOP act has had only a minor impact on early post-discharge opioid prescribing in patients undergoing fracture surgery. These findings question the efficacy of this type of legislation in combating opioid overprescribing in orthopaedic trauma. (Journal of Surgical Orthopaedic Advances 30(2)101-107, 2021).There are 16 million Hispanic people in the United States who rely on Spanish as their only effective method of communication. However, there is a scarcity of literature evaluating if patient education resources in Spanish meet the average American reading level or National Institute of Health (NIH) and American Medical Association (AMA) grade-level recommendations, especially in the field of orthopaedics. Representative orthopaedic search terms were input into Google and ten articles pertaining to patient education were selected. Videos, scientific journals, and surgical technique guides were excluded. Articles were then digitally analyzed and compared. Mean United States grade level equivalent was 11.26 ± 2.23 for English articles and 10.55 ± 1.45 for Spanish articles. English orthopaedic materials featured a significantly more difficult grade level (p less then 0.01) than equivalent Spanish works. Spanish orthopaedic materials generated in the United States featured significantly lower (p less then 0.01) readability scores than those written outside the United States. Our study demonstrated both English and Spanish materials were written at a high school level. Spanish materials were written at more appropriate grade-levels than their English counterparts. (Journal of Surgical Orthopaedic Advances 30(2)096-100, 2021).The purpose of this investigation was to evaluate the difference in response time, accuracy of radiographic interpretation, and frequency of changes in clinical management necessary after inaccurate reads when comparing orthopaedic and radiology providers. Data including provider response time, accuracy of radiographic interpretation and the frequency of changes in clinical management necessary after imaging reads was collected over a continuous two-month period at a Level I Trauma center. A total of 188 orthopedic injuries involving imaging were included. Orthopedic providers responded 203.2 minutes sooner than radiology providers. Accuracy of radiographic interpretation of the orthopaedic and radiology providers was 100% and 91%, respectively. Frequency of changes in clinical management after inaccurate interpretation of imaging by the orthopaedic and radiology provider was 0% and 7.6%, respectively. Based on our study, orthopaedic providers are significantly faster, more accurate, and make fewer mistakes affecting patient care while interpreting images of orthopaedic injuries than our radiology colleagues. (Journal of Surgical Orthopaedic Advances 30(2)093-096, 2021).A certificate of need (CON) permits a healthcare organization to build new facilities only if significant medical needs exist. Many states have implemented CON programs to prevent procedure overutilization and price inflation. We hypothesized that there are no differences in reimbursement or utilization for open and endoscopic carpal tunnel release (CTR) when comparing states with and without CON programs. We queried a private-payer database to identify open and endoscopic CTRs performed between 2007 and 2015. In total, 82,689 CTRs were identified 70,160 open, 12,529 endoscopic. Reimbursement increased for open procedures (compound annual growth rate [CAGR] 1.0% CON, 1.4% non-CON) but only marginally increased or decreased in the endoscopic group (CAGR -0.8% CON, 0.2% non-CON). Utilization increased across all settings, and was highest in the endoscopic CON group (CAGR 17.9%). Least growth was seen in the open non-CON group (CAGR 10.0%). Overall, CON programs may not actually decrease CTR spending or utilization. (Journal of Surgical Orthopaedic Advances 30(2)090-092, 2021).We sought to examine the relationship between opioid prescribing patterns and patient reported satisfaction with care. Opioid prescribing was characterized in terms of morphine equivalent daily dosing (MEDD), total morphine equivalent dosing (TMED), and total number of opioid prescriptions. A total of 1,666 opioid prescriptions were written for a TMED of 379,660 and a median MEDD of 204 (interquartile range [IQR] 195-269) from 2017-2019. Two hundred and forty-four patient satisfaction surveys were obtained for review and comparison. During the study period, 2,358 cases were performed, and no statistically significant differences were found with respect to case distribution among orthopaedic surgeons at our institution. High patient satisfaction, defined as achieving a 100 on a 0-to-100 scale, was found to have no association with MEDD (odds ratio = 0.968; 95% confidence interval [CI], 0.925-1.014), TMED (odds ratio = 1.00; 95% CI, 1.00-1.01), or total number of opioid prescriptions (odds ratio = 1.003; 95% CI, 0.
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