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Retinol binding protein One influences Xenopus anterior sensory development by way of all-trans retinoic acid signaling.
Results Twenty-seven participants completed the entire protocol and were included in the post-hoc analysis. Statistical analysis showed no interaction of group and time (p > 0.05) on anxiety scores. Both groups improved depressive and executive functions over time, without time and group interaction (p s less then 0.05). No adverse effects were reported in either intervention group. Conclusion rTMS did not improve anxiety symptoms following high frequency rTMS in persons with moderate to severe TBI. Clinical Trial Registration www.ClinicalTrials.gov, identifier NCT02167971.Introduction Orofacial pain features may negatively influence a person's well-being and vice versa. Some aspects of well-being can be measured with axis II instruments that assess patients' psychosocial and behavioral status. find more The aim of this study was to investigate associations between pain features and psychosocial variables as indicators of well-being. Materials and Methods Seven hundred ninety-nine anonymized datasets collected using the Web-based Interdisciplinary Symptom Evaluation (WISE) of patients reporting to the Interdisciplinary Orofacial Pain Unit, University of Zurich, between March 19, 2017 and May 19, 2019, were analyzed. Pain features including intensity, number of locations, impact, and duration were evaluated. Psychometric measures assessed pain-related catastrophizing and disability, illness perception, distress, anxiety, depression, injustice experience, dysmorphic concerns, and insomnia. Results Most patients were between 30 and 59 years old (58.3%), female (69.8%), working (66.0%), and iated with typical pain intensity at 0.39. The DCQ scores were moderately associated with pain extension at 0.41. Conclusions Moderate correlations of certain pain and well-being measures were found in patients reporting clinically relevant stress, injustice experience, and dysmorphic concern, all of which reflect impaired well-being. PHQ4 is suitable for routine distress screening in the clinical setting.Background and Objectives Amyloid-beta protein may lead to sleep disturbance and eventually develop cognitive impairment. Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) is a predictor of neurodegeneration, yet there have been limited studies evaluating the relationship between cognitive decline and amyloid accumulation in iRBD patients. The aim of this study is to investigate the clinical and sleep characteristics of iRBD patients and its association with amyloid deposition. Methods We enroll 23 iRBD patients (mean age, 65.8 years; male, 73.9%), and their mean history of clinically suspected RBD was 6.5 years. All underwent 18F-flutemetamol amyloid PET completed polysomnography (PSG) and questionnaires. Patients were classified into two groups according to amyloid deposition as amyloid positive and negative. Clinical and sleep parameters were compared between groups and were correlated with amyloid deposition, calculated as a standardized uptake value ratio (SUVR). Results Four patients (17.4%) were revealed to be amyloid positive, and they showed increased percentage of wake after sleep onset (WASO), stage N1, and stage N2 sleep and worse on the Stroop Word Color Test compared to amyloid negative patients. Global SUVR was correlated with total sleep time, sleep efficiency, WASO, and N1 sleep, and these sleep parameters were associated with a part of default mode network of brains such as orbitofrontal, dorsolateral pre-frontal, and left temporal areas. Conclusion iRBD patients with amyloid deposition have worse sleep quality than patients without amyloid. Relationship between fragmented sleep and amyloid deposition in the default mode network may be crucial to elucidate the disease progress of iRBD.[This corrects the article DOI 10.3389/fpsyg.2020.596080.].There are considerable gaps in our knowledge of how children develop abstract language. In this paper, we tested the Affective Embodiment Account, which proposes that emotional information is more essential for abstract than concrete conceptual development. We tested the recognition memory of 7- and 8-year-old children, as well as a group of adults, for abstract and concrete words which differed categorically in valence (negative, neutral, and positive). Word valence significantly interacted with concreteness in hit rates of both children and adults, such that effects of valence were only found in memory for abstract words. The pattern of valence effects differed for children and adults children remembered negative words more accurately than neutral and positive words (a negativity effect), whereas adults remembered negative and positive words more accurately than neutral words (a negativity effect and a positivity effect). In addition, signal detection analysis revealed that children were better able to discriminate negative than positive words, regardless of concreteness. The findings suggest that the memory accuracy of 7- and 8-year-old children is influenced by emotional information, particularly for abstract words. The results are in agreement with the Affective Embodiment Account and with multimodal accounts of children's lexical development.This article explores the connections between the construct of sexism and other sociodemographic and attitudinal variables, such as internalized homonegativity and heteronormative resistances, among psychology students. Both unrefined and inferential analyses were used with a representative sample of 841 psychology students from public universities in Madrid. Results showed higher levels of sexism, internalized homonegativity and low resistances to heteronormativity among groups of men, heterosexuals and conservatives. Interactions were found that showed a higher degree of hostile sexism in heterosexual people with respect to LGB and heterosexual men with respect to heterosexual women. Also, interactions were found to show a greater degree of heteronormative resistance in LGB people with respect to heterosexuals and left-wing women with respect to right-wing women. Correlations with sexism varied according to gender identity and sexual orientation. In addition, heteronormative resistances correlated negatively with sexism, while some components of internalized homonegativity correlated positively.
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