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Activation involving TMEM16A Ca2+-activated Cl- programs by simply ROCK1/moesin promotes breast cancers metastasis.
Several minerals are needed for thyroid hormone to work properly, such as iodine and iron. Iron is one of important essential trace elements that serves as co-factor for thyroid peroxidase (TPO). Those with iron deficiency have lower ferritin serum level than those who are normal. In particular, pregnant women with chronic energy deficiency (CED) have higher anemia risk than the otherwise. The study aimed to measure ferritin level, CED and hypothyroidism among pregnant women living in iodine deficiency disorders (IDD) endemic areas. A total of 37 pregnant women aged 18-45 y-oldwith pregnancy of 2 to 8 mo living in ID Dendemic of Dayakan and Watu Bonang Villages of Ponorogo District were include dinthestudy. Two different measurements were taken namely, anthropometric measurement of mid-upper arm circumference (MUAC) or upper circumference (UAC) which is more correct term to use, and blood markers of iodine and iron status were assessed using thyroid stimulating hormone (TSH), free thyroxine (fT4), and bloodferritin. Among pregnant women, 27% had hypothyroidism and 54.05% had iron depletion, with 30% had both conditions. AZD6738 The hypothyroidism was higher in pregnant women had CED than those non-CED, 50% vs. 18.5%. No significant correlation (p≥0.05) between hypothyroidism and both ferritin and CED, but adjusted odds ratio (AOR) was found at 7.7 (95% CI 1.2-52.9), indicated more than four times higher risk of hypothyroidism in pregnant women with CED than the otherwise. Hypothyroidism in pregnant women living in Ponorogo was not caused by iron deficiency, but allegedly by lack of other nutritional intake. Conclusion Integrated and sustainable efforts to improve nutritional status is needed since pre-conception and throughout pregnancy.It is well-established that school feeding program (SFP) has been provided significant nutritional and health beneficial effects to student namely. SFP or school meal services program without nutritionist have lack of food delivery system, nutrient quality and health promotion. Thus, the aim of this study was to analyze the influence of nutritionist-based food service delivery system on food and nutrient quality of school lunch program in primary school.
This study used cross-sectional design in two primary school in Indonesia that use different models of SFP (on-site (public-owned-public-managed) kitchen, off-site (ready-to-eat foods will be taken to school, preparation, cooking and sprinkling processes are carried out outside the school (catering)). Comparison analysis was done by using t-test independent.

We found that food service on-site model with nutritionist (Al Muslim) in school meal service, menu quality and hygiene sanitation better than Al Hidayah primary school (catering without nutritionist). The adequacy of nutrients particularly protein, calcium and iron in Al Hidayah students was significantly different than Al Muslim student (p-value<0.05).

Primary school need to collaborate with nutritionist to plan the menu and food service system to achieve optimal nutritional status.
Primary school need to collaborate with nutritionist to plan the menu and food service system to achieve optimal nutritional status.Poor nutritional status or stunting still becomes a public health problem in Indonesia, with prevalence of 37.2% in 2013. Some research results show that stunted children have lower cognitive development than normal children. This study aims to assess whether there is an effect of giving multiple-nutrient biscuits and psychosocial parenting education on height and development of children under the age of three (toddlers). This study used quasi experimental design. The treatment was given for 2 mo to 28 stunted children who were divided into 3 groups, namely (1) multiple-nutrient biscuits (2) psychosocial parenting education (3) multiple-nutrient biscuits and psychosocial parenting education. Multiple-nutrients biscuit was given 12 pieces a day for 2 mo. Meanwhile, psychosocial parenting education was given direcly by psychologist in the form of lectures, brainstorming and role play. In order to identify the effect of treatment on children's height and development, the data obtained was analyzed using paired t-test, while the analysis of differences between treatment groups was carried out using analysis of variance (ANOVA). The results showed that giving psychosocial parenting education significantly increased height, children's nutritional status based on height by age index, and improved cognitive development among toddlers. Giving multiple-nutrient biscuits and psychosocial parenting education significantly increased height and cognitive development among toddlers. In order to overcome children's growth and development problem, nutrition interventions need to be carried out along with the provision of education about maternal parenting to children.Despite the present of national policy support, the prevalence of early breastfeeding initiation in Indonesia are still low. Research has shown that health care workers are the most reliable source for breastfeeding advice, but sadly they were often lacking in capacity. The aim of the study to assess the involvement of civil society organization (CSO) and its associated factors in facilitating the implementation of Ten Steps for Successful Breastfeeding (TSSB) based on health care workers' perspectives in Malang and Sidoarjo districts, East Java Province, Indonesia. We used qualitative approach to in-depth interview 117 participants and conducted 14 FGDs in Sidoarjo and Malang East Java. the PARiHS framework was used to identify the role of CSO in facilitating the BFHI implementation from the health workers perspective to offer insight on the facilitation process and development of future recommendations. The study found that the health care workers' have good knowledge on the benefits of breastfeeding with significant portion of the knowledge that they hold are coming from trainings provided by the CSO. There was cultural context barriers within the community, where grandmothers are considered as an important influence factor esspecially for working mothers. The implementation of training by the CSO was considered appropriate due to its ability to address some pressing structural obstacles and provide not only training to improve evidence but also help in addressing other contextual barriers. The CSO has offered opportunities not only for dissemination of evidence-based intervention but also to close gaps on resources provision to attend courses.
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