Notes

Friendships associated with D. frondosa-derived inhibitory peptides in opposition to angiotensin I-converting enzyme (_ design), α-amylase along with lipase.
Rare plant species often suffer less damage than common species because of positive density-dependent herbivory, and it has been suggested that this 'rare species advantage' fosters plant species coexistence. However, it is unknown whether rare species have an advantage when pollination interactions are also considered. Epigenetics inhibitor We hypothesized that a 'positive density-dependent pollination success' across plant species would result in common plants experiencing higher seed set rates compared to rare species, and that positive density-dependent effects would negate or even override the positive density-dependent damage due to herbivory resulting in higher seed loss rates in common plant species. We tested this hypothesis by concurrently examining a plant-predispersal seed predator system and a plant-pollinator system for 24 Asteraceae species growing in an alpine meadow community (Sichuan Province, China). Having previously reported a positive density-dependent effect on seed loss rates due to seed predators, we here focus on the density-dependent effects on pollination success by investigating pollinator species richness, visitation frequencies and seed set rates for each plant species. We also estimated the seed output rate of each plant species as the product of seed set rate and the rate of surviving seeds (i.e. 1 - the seed loss rate). Consistent with our hypothesis, a positive density-dependent effect was observed for pollinator species richness, visitation frequencies and seed set rates across plant species. Moreover, the positive effect overrode the negative density-dependent effect of herbivores on seed production, such that common species tended to have a higher seed output rate than rare species (i.e. we observed a 'rare species disadvantage'). These results indicate that the low seed output rate of rare species might result from a pollination limitation, and that both mutualistic and antagonistic interactions should be examined simultaneously to fully understand plant species coexistence in local communities.Numerous studies have shown that climate change affects the timing of migration and bird laying dates, but the resulting changes in the duration of breeding seasons and their fitness consequences remain largely unknown. We compared breeding parameters of 343 individually marked female Eurasian reed warblers, a multi-brooded migratory passerine, studied in the same area in 1980-1983 and 2005-2012. The latter period was warmer, with mean temperatures during the breeding season higher by 1.5°C on average. As, in recent years, birds arrive earlier from wintering areas and the breeding season of the population is longer, we hypothesized it should result in the increased re-nesting opportunities of individual females. We found that breeding periods of individual females (from building of the first nest till the end of caring for last fledglings/last nest failure) in the current century have extended by 2 weeks compared to the 1980s. In the 2000s, females produced 75% more fledglings annually than females in the 1980s (2.8 vs. 1.6, respectively). The proportion of females raising second broods increased from 2.7% to 23.6% between the first and the second study period while the share of females that did not produce any young annually decreased from 48.1% to 15.5%. The higher offspring production in recent years was related to more successfully fledged broods and an earlier start of breeding, which secured more time to re-nest. Higher female parental effort in recent years was not manifested in the reduction of the female apparent survival it was almost identical in the two study periods (0.30 vs. 0.31). We conclude that prolonged reproductive seasons might be beneficial for some species. Identifying causes and consequences of changes in the duration of breeding seasons may be essential to predict demography of populations under changing climatic conditions.
Changes in epilepsy care during the COVID-19 pandemic required to reassess the patient-specialist interaction in the context of telehealth and future vaccination campaigns.

The aims were to outline changes in neurologists' experience when providing care for patients with epilepsy (PWE) and to investigate how neurologists perceive telehealth and vaccination.

We conducted an anonymous cross-sectional online survey among members of the Lithuanian Association of Neurology.

We received 104 completed forms by adult (74, 71.15%) and pediatric neurologists (30, 28.85%). A decrease in epilepsy consultations was noted by 76 (73.1%) specialists, and up to 26 (25.0%) could not provide diagnostic tests at a usual rate. Most respondents (99, 95.2%) would recommend the COVID-19 vaccine for patients at risk. Telehealth was valued as a useful tool in epilepsy care, especially if combined with timely diagnostic and treatment options (Kruskal-Wallis chi-square=10.392, p=.034 and F[4,99]=3.125, p=.018, respectively). According to 85 (81.7%) respondents, video calls could substitute in-person visits in at least half of all consultations.

Despite disrupted epilepsy care, neurologists may benefit from telehealth when providing services for PWE and become vaccination advocates to mitigate the spread of preventable infections.
Despite disrupted epilepsy care, neurologists may benefit from telehealth when providing services for PWE and become vaccination advocates to mitigate the spread of preventable infections.
Pre-eclampsia and delivery of small-for-gestational-age (SGA) neonates can be predicted from the first trimester. A Gaussian model for prediction of PE has recently been described, although its capacity to predict SGA is still unknown.

This was a secondary analysis of a prospective cohort study conducted at Vall d'Hebron University Hospital (Barcelona) in 2483 single pregnancies from October 2015 to September 2017. Mean arterial blood pressure and mean uterine artery pulsatility index were recorded at the first-trimester scan. Serum concentrations of placental growth factor and pregnancy-associated plasma protein-A were assessed between 8
and 13
weeks. The predictive capacities of early (<32weeks) and preterm (<37weeks) SGA were tested.

For SGA without pre-eclampsia, detection rates of 25.0% (95% confidence interval [CI] 0-75.0) for early SGA and 14.3% (95% CI 3.6-28.6) for preterm SGA were achieved. For SGA with pre-eclampsia, the algorithm showed detection rates of 100.0% (95% CI 25.0-100.0) for early SGA and 56.
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