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Can having a baby influence pelvic floor well-designed anatomy? A retrospective examine.
Skeletal muscle comprises a heterogeneous population of myoblasts and fibroblasts. Autologous skeletal muscle myoblasts are transplanted to patients with ischemia to promote cardiac regeneration. In damaged hearts, various cytokines secreted from the skeletal muscle myoblasts promote angiogenesis and consequently the recovery of cardiac functions. However, the effect of skeletal muscle fibroblasts co-cultured with skeletal muscle myoblasts on angiogenic cytokine production and angiogenesis has not been fully understood. To investigate these effects, production of vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) was measured using the culture medium of monolayers prepared from various cell densities (mono-culture) and proportions (co-culture) of human skeletal muscle myoblasts (HSMMs) and human skeletal muscle fibroblasts (HSMFs). HSMM and HSMF mono-cultures produced VEGF, whereas HSMF mono-culture produced HGF. The VEGF productivity observed in a monolayer comprising low proportionsis in the skeletal muscle cell sheets. This approach can be used to improve transplantation efficiency of engineered tissues.Reduced external knee adduction moments in the second half of stance after total hip replacement have been reported in hip osteoarthritis patients. This reduction is thought to shift the load from the medial to the lateral knee compartment and as such increase the risk for knee osteoarthritis. The knee adduction moment is a surrogate for the load distribution between the medial and lateral compartments of the knee and not a valid measure for the tibiofemoral contact forces which are the result of externally applied forces and muscle forces. The purpose of this study was to investigate whether the distribution of the tibiofemoral contact forces over the knee compartments in unilateral hip osteoarthritis patients 1 year after receiving a primary total hip replacement differs from healthy controls. Musculoskeletal modeling on gait was performed in OpenSim using the detailed knee model of Lerner et al. (2015) for 19 patients as well as for 15 healthy controls of similar age. Knee adduction moments were calculatedhe contralateral leg in OA patients after total hip replacement (THR). Musculoskeletal modeling using a detailed knee model can be useful to detect differences in the load distribution between the medial and lateral knee compartment which cannot be verified with the knee adduction moment.The purpose of this study was to investigate differences in Froude efficiency (η F ) and active drag (D A ) between front crawl and backstroke at the same speed. η F was investigated by the three-dimensional (3D) motion analysis using 10 male swimmers. The swimmers performed 50 m swims at four swimming speeds in each technique, and their whole body motion during one upper-limb cycle was quantified by a 3D direct linear transformation algorithm with manually digitized video footage. Stroke length (SL), stroke frequency (SF), the index of coordination (IdC), η F , and the underwater body volume (UWV body ) were obtained. D A was assessed by the measuring residual thrust method (MRT method) using a different group of swimmers (six males) due to a sufficient experience and familiarization required for the method. A two-way repeated-measures ANOVA (trials and techniques as the factors) and a paired t-test were used for the outcomes from the 3D motion analysis and the MRT method, respectively. Swimmers had 8.3% longer SL, 5.4% lower SF, 14.3% smaller IdC, and 30.8% higher η F in front crawl than backstroke in the 3D motion analysis (all p less then 0.01), which suggest that front crawl is more efficient than backstroke. Backstroke had 25% larger D A at 1.2 m⋅s-1 than front crawl (p less then 0.01) in the MRT trial. A 4% difference in UWV body (p less then 0.001) between the two techniques in the 3D motion analysis also indirectly showed that the pressure drag and friction drag were probably larger in backstroke than in front crawl. In conclusion, front crawl is more efficient and has a smaller D A than backstroke at the same swimming speed.As in any biophysical electrode-tissue environment, impedance measurement shows a complex relationship which reflects the electrical characteristics of the medium. In cochlear implants (CIs), which is mostly a stimulation-oriented device, the actual clinical approach only considers one arbitrary time-measure of the impedance. However, to determine the main electrical properties of the cochlear medium, the overall impedance and its subcomponents (i.e., access resistance and polarization impedance) should be described. We here characterized, validated and discussed a novel method to calculate impedance subcomponents based on CI measurement capabilities. With an electronic circuit of the cochlear electrode-tissue interface and its computational simulation, the access resistance and polarization impedance were modeled. Values of each electrical component were estimated through a custom-made pulse delivery routine and the acquisition of multiple data points. Using CI hardware, results fell within the electronic components nominal errors (± 10%). Considering the method's accuracy and reliability, it is readily available to be applied in research-clinical use. check details In the man-machine nature of the CI, this represents the basis to optimize the communication between a CI electrode and the spiral ganglion cells.A spherical iron oxide precursor was prepared using a solvothermal method, and then treated thermally at 400°C to obtain α-Fe2O3 nanoparticles. The structures and morphology of the as-obtained products were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). The results showed that the diameter of the α-Fe2O3 nanoparticles was approximately 500 nm. In addition, we formed the α-Fe2O3 nanoparticles into a thick film as a gas sensor and performed a gas sensing test. When the working temperature was set at 250°C, the α-Fe2O3 nanoparticle displayed very good selectivity and high sensitivity for trimethylamine (TMA). The minimum detection was as low as 1 ppm, and the response value for 100 ppm TMA gas was 27.8. Taken together, our findings illustrated that the α-Fe2O3 nanoparticles could be used as a gas-sensitive material to test the freshness of fish.
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