Notes

Aided hatching upon aided pregnancy (in vitro fertilisation (IVF) and also intracytoplasmic sperm procedure (ICSI)).
During and after the 2016 United States (U.S.) presidential election, discriminatory policies and stigmatizing rhetoric have been increasingly directed toward the transgender community at state and national levels. Wnt-C59 chemical structure Transgender and/or nonbinary (TNB) adolescents, already at elevated risk for poorer health relative to their cisgender (nontransgender) peers, may have been adversely impacted by the shifting sociopolitical climate. This secondary analysis used qualitative data from the Trans Teen and Family Narratives Project to investigate how perceived shifts in the sociopolitical climate following the 2016 election affected families with TNB adolescents in the New England region of the U.S. (states of Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont). Data included two waves of semistructured interviews conducted with TNB adolescents and their caregivers and siblings (N = 20 families, 60 family members). Two coders analyzed transcripts using a thematic analysis approach. Emergent themes included contemporary life for trans people in America (e.g., being discriminated against and dehumanized), perceptions of the national sociopolitical climate (e.g., anger toward political figures), forms of resistance and advocacy (e.g., confronting misinformation), and factors amplifying or buffering effects of the sociopolitical climate (e.g., the formation of alliances or coalitions within the family). Findings indicate the 2016 election spurred the redefinition of communication boundaries within, and outside, the immediate family, particularly regarding online communication and social media. TNB adolescents and their families anxiously anticipated changes in the sociopolitical climate and their foreseen impact on TNB adolescents' rights and safety. Implications for family therapy, intervention design, and policy reform are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Reports the retraction of "Twenty-first birthday drinking Extreme-drinking episodes and white matter microstructural changes in the fornix and corpus callosum" by Cassandra L. Boness, Ozlem Korucuoglu, Jarrod M. Ellingson, Anne M. Merrill, Yoanna E. McDowell, Constantine J. Trela, Kenneth J. Sher, Thomas M. Piasecki and John G. Kerns (Experimental and Clinical Psychopharmacology, 2020[Oct], Vol 28[5], 553-566). The explanation for the retraction In preparing to use the DTI images for secondary data analysis, it was discovered that multiple participants had the wrong DTI data included for Session 1 analyses. This was due to a file transfer error that incorrectly substituted another participant's DTI data for the correct DTI data. In correcting the error and reanalyzing the data, our findings changed in ways that were nontrivial and, thus, exceed what would be appropriate for a corrigendum. (The following abstract of the original article appeared in record 2019-72844-001.) The 21st birthday celebration is charame-drinking episode. Region of interest analyses demonstrated increased fractional anisotropy in the posterior fornix (p less then .0001) and in the body of the corpus callosum (p = .0029) from pre- to postbirthday celebration. These results suggest acute white matter damage to the fornix and corpus callosum following an extreme-drinking episode, which is especially problematic during continued neurodevelopment. Therefore, 21st birthday drinking may be considered an important target event for preventing acute brain injury in young adults. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Given high relapse rates and the prevalence of overdose deaths, novel treatments for substance use disorder (SUD) are desperately needed for those who are treatment refractory. The objective of this study was to evaluate the safety of deep brain stimulation (DBS) for SUD and the effects of DBS on substance use, substance craving, emotional symptoms, and frontal/executive functions. DBS electrodes were implanted bilaterally within the Nucleus Accumbens/Ventral anterior internal capsule (NAc/VC) of a man in his early 30s with >10-year history of severe treatment refractory opioid and benzodiazepine use disorders. DBS of the NAc/VC was found to be safe with no serious adverse events noted and the participant remained abstinent and engaged in comprehensive treatment at the 12-week endpoint (and 12-month extended follow-up). Using a 0-100 visual analog scale, substance cravings decreased post-DBS implantation; most substantially in benzodiazepine craving following the final DBS titration (1.0 ± 2.2) compared to baseline (53.4 ± 29.5; p less then .001). A trend toward improvement in frontal/executive function was observed on the balloon analog risk task performance following the final titration (217.7 ± 76.2) compared to baseline (131.3 ± 28.1, p = .066). FDG PET demonstrated an increase in glucose metabolism in the dorsolateral prefrontal and medial premotor cortices at the 12-week endpoint compared to post-surgery/pre-DBS titration. Heart Rate Variability (HRV) improved following the final titration (rMSSD = 56.0 ± 11.7) compared to baseline (19.2 ± 8.2; p less then .001). In a participant with severe, treatment refractory opioid and benzodiazepine use disorder, DBS of the NAc/VC was safe, reduced substance use and craving, and improved frontal and executive functions. Confirmation of these findings with future studies is needed. (PsycInfo Database Record (c) 2021 APA, all rights reserved).Driving after cannabis use (DACU) is a significant public health concern and represents one of the riskiest cannabis-related behaviors. Though years of research has demonstrated that cannabis use impairs driving ability, many college students report believing that cannabis use does not impair their driving abilities. This perception of low danger may contribute to a permissive attitude toward DACU. The present proof-of-concept pilot study examined the preliminary efficacy of a mobile phone-based intervention with personalized feedback and text messaging to increase perceptions of dangerousness of DACU. Participants were 77 college cannabis users (65.8% women; average age = 21.2; 88.3% Caucasian) who endorsed DACU at least three times in the past 3 months. After completing baseline measures, participants were randomly assigned to one of three conditions (a) personalized feedback plus interactive text messaging (PFT), (b) personalized feedback only (PF), or (c) informational control (IC). Participants completed outcome measures 3 months post intervention.
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