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This paper is evidence for the investor in the healthcare sector to invest more in HITs and health information quality, where the expected results are productivity improvement, performance leveraging and error reduction. The research originality is to introduce new evidence support literature form the Middle East countries is the main contribution of this paper.Wharton's jelly derived-mesenchymal stem cells (WJ-MSCs) have a same developmental origin with primordial germ cells. WJ-MSCs perhaps differentiate into oocyte and germ like-cells (OLCs/GLCs) in the presence of appropriate inducers. Human follicular fluid (FF) and cumulus cells conditioned medium (CCM) are naturally rich sources for oocyte development. The aim of this study was to evaluate WJ-MSCs potential for differentiating into OLCs and GLCs exposed to FF and CCM. WJ-MSCs were cultured in two different induction media (10% FF, 10% CCM) for 21 days. Morphological changes and expression of developmental genes were evaluated on days 0, 7, 14 and 21 of culture. Also, on 21st day of culture, the expression of oocyte and germ cell proteins investigated using immunofluorescence staining. Appearance of round shaped cells from 7th day onwards indicated that WJ-MSCs can differentiate into OLCs when exposed to FF and CCM. The size of produced OLCs and expression of oocyte specific genes and proteins were increased more positively in FF group rather than CCM group. Although, WJ-MSCs could differentiate into OLCs by FF and CCM, however, the induction potential of FF for producing OLCs was better than CCM.Lactic acid is an organic compound produced via fermentation by different microorganisms that are able to use different carbohydrate sources. Lactic acid bacteria are the main bacteria used to produce lactic acid and among these, Lactobacillus spp. have been showing interesting fermentation capacities. The use of Bacillus spp. revealed good possibilities to reduce the fermentative costs. Interestingly, lactic acid high productivity was achieved by Corynebacterium glutamicum and E. coli, mainly after engineering genetic modification. Fungi, like Rhizopus spp. can metabolize different renewable carbon resources, with advantageously amylolytic properties to produce lactic acid. Additionally, yeasts can tolerate environmental restrictions (for example acidic conditions), being the wild-type low lactic acid producers that have been improved by genetic manipulation. Microalgae and cyanobacteria, as photosynthetic microorganisms can be an alternative lactic acid producer without carbohydrate feed costs. For lactic acid production, it is necessary to have substrates in the fermentation medium. Different carbohydrate sources can be used, from plant waste as molasses, starchy, lignocellulosic materials as agricultural and forestry residues. Dairy waste also can be used by the addition of supplementary components with a nitrogen source.Leaked methane from natural gas distribution pipelines is a significant human and environmental health problem in urban areas. To assess this risk, urban mobile methane leak surveys were conducted, using innovative methodology, on the streets of Hartford, Danbury, and New London, Connecticut, in March 2019. The Hartford survey was done to determine if results from a 2016 survey (Keyes et al., 2019) were persistent, and surveys in additional towns were done to determine if similar findings could be made using an identical approach. Results show that Hartford continues to be problematic, with approximately 3.4 leaks per road mile observed in 2016 and 4.3 leaks per mile estimated in 2019, similar to that previously found in Boston, Massachusetts (Phillips et al., 2013). A preliminary estimate of methane leaks in Hartford is 0.86 metric tonnes per day (or 313 metric tonnes per year), equivalent to 42,840 cubic feet per day of natural gas, and a daily gas consumption of approximately 214 U.S. households. Moreover, the surveys and analyses done for Danbury and New London also reveal problematic leaks, particularly for Danbury with an estimated 3.6 leaks per mile. Although road miles covered in New London were more limited, the survey revealed leak-prone areas, albeit with a range of methane readings lower than those in Hartford and Danbury. Data collection methods for all studies is first reported here and are readily transferable to similar urban settings. This work demonstrates the actionable value that can be gained from data-driven evaluations of urban pipeline performance, and if supplemented with a map of leak-prone pipe geo-location, and information on pipeline operating pressures, will provide a spatial database facilitating proactive repair and replacement of leak-prone urban pipes, a considerable improvement compared to reactive mitigation of human-reported leaks. While this work pertains to the selected urban towns in the Northeast, it exemplifies issues and opportunities nationwide in the United States.This article concentrates on the non-Newtonian fluid flow over the oscillating surface. The rate of heat conduction of the fluid is enhanced by taking nanofluids in it. The two-phase nanofluid flow model is revealed. The flow is explored in the existence of oblique stagnation point flow. The analysis is incorporated for the Riga plate in the existence of an oblique stagnation point. Riga plate is well-known as an electromagnetic actuator contains permanent magnets and a spanwise aligned array of alternating electrodes attached on a plane surface. The dimensional equations satisfying the stated assumptions of the fluid flow are presented utilizing the Navier-Stokes equation. Pralsetinib concentration Fourier law is incorporated in the evaluation of heat flux. The analysis is examined in the fixed frame of reference. The obtained partial differential equation will be critically examined suitable similarity transformation will be chosen to convert these flow developed equations into higher non-linear ordinary differential equations (ODE) and these equations of motion are tackled by mathematical techniques like bvp4c method in Maple. From this study, it is determined that due to the effect of the Riga parameter the velocity field enhances, and also due to the effects of Casson parameter the velocity field increases. The effect of immerging of parameters is mentioned by tables and graphs. Moreover, the flow behavior is also confirmed by streamlines. The Casson fluid parameter makes to get faster the fluid velocity. The system heats up by the impact of Joule heating and dissipation.
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