Notes

How Equivalent are Bacterial Electrochemical Techniques around the Globe? A good Electrochemical and Microbiological Cross-Laboratory Review.
Post-stroke cognitive deficits and dementia Abstract. Prediction of stroke outcome remains challenging due to a large inter-individual variability. For a long time, research on stroke outcome has been mainly confined to post-stroke motor deficits, whereas post-stroke cognitive decline has been less investigated though being an often reason for dependency and disability. Post-stroke cognitive impairment demonstrate high inter-individual variability, which is expected to increase further due to the increasing life expectancy and number of patients with pre-stroke brain pathology and cognitive deficits. There exist different types and patterns of post-stroke cognitive impairment i) the deficits in one or several cognitive domains meaning the variability in neuropsychological profiles; ii) the decline might vary from mild to manifested dementia comprising a wide spectrum in severity; iii) with occurrence immediately after stroke or with delayed manifestation several months later without obvious reasons. Patients ight help in screening of risk patients, establishment of individualized therapeutic approaches, and enable knowledge transfer.Atrial fibrillation and ischaemic stroke current treatment and personalized risk prediction of intracerebral haemorrhage Abstract. Atrial fibrillation is a major cause of stroke. Management of patients with atrial fibrillation and stroke is challenging. In this review article, based on the most recent scientific literature, the following questions are discussed 1) When is the optimal point in time to start anticoagulation after a recent stroke? 2) How to treat patients with atrial fibrillation that have a stroke despite anticoagulant therapy? 3) What is the added value of MRI for personalized risk-prediction of intracerebral hemorrhage? 4) How to treat patients with atrial fibrillation after intracerebral hemorrhage? We provide recommendations for daily clinical management.Intracerebral haemorrhage - acute event and chronic disease Abstract. Intracerebral hemorrhage accounts for 10-15% of all strokes and approximately 1'500-2'000 patients per year in Switzerland. Acute treatment by multi-disciplinary experts at certified stroke units and stroke centers is important to provide optimal care. A simple ABC-care bundle (revert anticoagulation, control blood pressure, inform neurosurgeon) decreases poor outcome. selleck inhibitor Despite a high mortality, one third of patients are functionally independent after intracerebral hemorrhage contradicting widespread pessimism. About 80% of all intracerebral hemorrhage are attributable to different types of cerebral small vessel disease. Relative and absolute risks of recurrent hemorrhage and ischemic stroke differ significantly. Patients with intracerebral hemorrhage are vascular high-risk patients with chronic cerebrovascular disease. Long-term outpatient management should include neurovascular specialists to deal with important decisions (blood pressure management, antithrombotic therapy including anticoagulation, specialized neurorehabilitation to improve neurocognitive deficits, therapy of possible complications such as epilepsy) to provide optimal and individual care to patients. Currently ongoing randomized controlled trials will provide important results in the next years further improving treatment of intracerebral hemorrhage.Stroke patient education scientific evidence, practical application Abstract. Stroke is a sudden and brutal event that changes every aspect of daily life. The patient and his family will need to develop skills in self-management of this chronic disease over the long term, managing risk factors, lifestyle changes and consequences of stroke. In recent years, randomized clinical trials have demonstrated the effectiveness of patient education and of several lifestyle-changing interventions adopted after a stroke. We summarize this scientific knowledge and describe the practical aspects of implementing a patient education program in a stroke unit, an essential approach in the treatment and follow-up of stroke patients.Healthy diet in primary and secondary prevention of stroke Abstract. An unhealthy diet is one of the modifiable risk factors for stroke. The world population's diet is suboptimal. Healthy and nutritious food such as whole grain, vegetables, fruit and fish is not consumed enough, and unhealthy food such as sweetened beverages, processed meat and salty food takes up a higher proportion of the diet than recommended. We also see this imbalance in Switzerland. After a thorough literature review, we summarize the current findings about different diets and food groups affecting the risk of stroke. Generally, a diet low in salt and rich in potassium, vegetables, fruit, whole grains and unsaturated fats, moderate consumption of fish and low intake of meat is recommended to decrease the risk of stroke. The Mediterranean diet comprises all these aspects and was shown to reduce the stroke risk considerably. Generally, a high variety of food has more impact than supplementation of vitamins, minerals and micronutrients.
People with Huntington's disease (HD) often become institutionalized and more frequently die away from the home setting. The reasons behind differences in end-of-life care are poorly understood. Less than 5% of people with HD report utilization of palliative care (PC) or hospice services, regardless of the lack of curative therapies for this neurodegenerative disease. It is unknown what factors are associated with in-patient specialty PC consultation in this population and how PC might be related to discharge disposition.

To determine what HD-specific (e.g., psychosis) and serious illness-specific factors (e.g., resuscitation preferences) are associated with PC encounters in people with HD and explore how PC encounters are associated with discharge disposition.

We analyzed factors associated with PC consultation for people with HD using discharge data from the National Inpatient Sample and the Nationwide Inpatient Sample (NIS), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Resears to meet the needs of persons with HD.
Among patients with HD, economic factors, depression, and serious illness-specific factors were associated with PC, and PC was associated with discharge disposition. These findings have implications for the adaptation of inpatient PC models to meet the needs of persons with HD.
Here's my website: https://www.selleckchem.com/products/tak-981.html