Notes

Multiplexed recording together with uncorrelated computer-generated reference point designs inside coaxial holographic info storage.
Results of studies on the association between periodontal disease (PD) and Alzheimer's disease (AD) or mild cognitive impairment (MCI) are inconsistent, and a previous meta-analysis published in 2017 included inadequate studies and is thus outmoded. This study aims to systematically evaluate the correlation between PD and the risk of AD or MCI.

The following electronic databases were screened by two investigators independently, without restriction of language CENTRAL (Cochrane library), PubMed (MEDLINE), EMBASE, China National Knowledge Interne, China Science and Technology Journal Database, Wanfang Data, www.ClinicalTrials.gov, and WHO International Clinical Trials Registry Platform. Meta-analysis was conducted using random-effects model or fixed-effects model according to the heterogeneity of included studies.

Thirteen eligible studies, of which eight reported AD (291 114 participants) and eight reported MCI (4805 participants), were included in this meta-analysis. The pooled results showed that compared with the non-PD population, the risk of AD and MCI in PD patients was significantly higher (for AD odds ratio (OR)=1.78, 95% CI 1.15-2.76; for MCI OR=1.60, 95% CI 1.24-2.06), and especially in those with severe PD (for AD OR=4.89, 95% CI 1.60-14.97; for MCI, OR=2.32, 95% CI 1.24-4.36).

This meta-analysis indicated that PD was related to an elevated risk of AD and cognitive impairment, and that it should receive early intervention.
This meta-analysis indicated that PD was related to an elevated risk of AD and cognitive impairment, and that it should receive early intervention.Organosulfurs are promising cathode materials for rechargeable metal batteries due to their high capacities, diverse structures, and electrochemical properties. Herein, the electrochemical behavior of three organosulfur compounds, i.e., 4,4'-thiobisbenzenethiol (TBBT), 1,4-benzenedithiol (1,4-BDT), and diphenyl disulfide (DPDS), is revealed in room-temperature rechargeable sodium (Na) batteries, which show significantly improved performances when sodiated Nafion membranes are used. Large oligomers of organosulfur can be formed during charging, and they are readily blocked by the nanosized ion-conducting clusters in the Nafion membrane. In addition, large organosulfur monomers can also be blocked. Only 5.4% of TBBT diffuses through the Nafion membrane after 800 h. The Na|TBBT cell sustains 77% of the theoretical capacity after 300 cycles (2420 h). Moreover, the Na|TBBT redox flow cell shows promising rechargeability. Due to the medium molecular size, the organosulfur oligomers are expected to provide a new avenue to develop high-capacity chalcogen cathodes, besides inorganic S and S-containing polymers.
To evaluate the incidence of perioperative infections without antimicrobial prophylaxis in patients undergoing clean surgeries for adrenal and renal tumors.

We prospectively enrolled 1362 consecutive patients who underwent minimally invasive adrenalectomy (n=303), radical nephrectomy (n=499), and partial nephrectomy (n=560) using the gasless laparoendoscopic single-port surgery technique between 2005 and 2019. In 1059 patients, antimicrobial prophylaxis was not administered. The remaining 303 patients were considered at high risk for infection and received single-dose antimicrobial prophylaxis. The endpoint was the incidence of perioperative infections within 1month from the surgery date. Perioperative infections were classified into surgical site infections, urinary tract infections, and remote infections.

Seventy-four patients whose collecting systems were opened during partial nephrectomy were excluded, and the remaining 1013 patients with nonuse of antimicrobial prophylaxis and 275 patients with single-dose antimicrobial prophylaxis were retrospectively analyzed. The incidence of superficial surgical site infections, deep/organ-space surgical site infections, urinary tract infections, and remote infections was 1.6%, 0.7%, 2.8%, and 1.3%, respectively, in patients with nonuse of antimicrobial prophylaxis and 0.4%, 1.8%, 1.5%, and 1.5%, respectively, in patients with single-dose antimicrobial prophylaxis. All patients who developed perioperative infections were successfully treated. No clinical or surgical variables were significantly associated with the incidence of surgical site infections. One limitation of the present study was its nonrandomized and noncontrolled design.

In minimally invasive clean surgeries for adrenal and renal tumors, antimicrobial prophylaxis is not necessary when individual risk of infection is considered low.
In minimally invasive clean surgeries for adrenal and renal tumors, antimicrobial prophylaxis is not necessary when individual risk of infection is considered low.The supplemental feeding of wildlife is a worldwide phenomenon. The most widespread and socially accepted example is bird feeding. Commercial hedgehog (Erinaceus europaeus L.) diets are readily available in Switzerland. To test the hypothesis that commercial hedgehog diets are nutritionally inadequate, the following parameters (as taken from the label) of five commercial diets (three dry and two wet) were compared to the natural diet of E. selleck compound europaeus List of feed materials, crude ash (CA), crude protein (CP), crude fibre (CF), ether extract (EE) and nitrogen-free extracts (NfE). To test the second hypothesis, that feed labels of commercially available hedgehog diets in Switzerland are in accordance with Swiss and European law, the following parameters were assessed Type of feed, net quantity, moisture content, instructions for proper use, list of the feed materials and claims. In all dry diets, the first ingredient was cereals (38.8%-50%), whereas in both wet diets, it was meat and meat by-products (51% in one product). Only one product had a CP content comparable to that of the natural diet and four products had a higher NfE content. Overall, the wet products were more comparable to the natural diet, especially regarding CP and NfE content. Of the five examined diets, three were labelled as complete feeds and two as compound feeds. The label analysis revealed inaccuracies and possible misleading information on two products. In conclusion, the use of commercial dry hedgehog diets should be discouraged as they do not resemble the natural diet of E. europaeus and are likely nutritionally inadequate. The commercial wet hedgehog diets should only be used supplementary. The feed labels of commercially available hedgehog diets were not always in compliance with Swiss and European law. The public should be educated about feeding E. europaeus and the risks of commercial diets for wildlife.
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