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DeepG4: A deep understanding approach to predict cell-type specific active G-quadruplex locations.
CFA was performed on the second part of the sample (n = 135) to test the fitness of the 3-factor solution. According to CFI (0.91), NFI (0.91), NNFI (0.90), IFI (0.91), PNFI (0.77), GFI (0.75) AGFI (0.70), PGFI (0.62) and chi-square (540.31) indexes, the model had acceptable fitness. Cronbach's alpha was employed to measure the internal consistency and it revealed to be at a good to excellent level (behavioral problems related to oppositional defiant = 0.88; behavioral problems related to inattentive = 0.84; behavioral problems related to conduct = 0.74). The 3-factors subscales were associated with total difficulties, internalizing and externalizing SDQ, indicating the good convergent validity of F-ECBI. Conclusion The F-ECBI has good psychometric properties in Iran and can be employed as a useful instrument for measuring children's behavioral problems.Objective Multiple sclerosis (MS) is a chronic neurological disease that could aggressively affect patients' quality of life in most instances. This study aimed to compare the effectiveness of an existential-spiritual psychotherapy with a cognitive-behavioral therapy on quality of life and meaning in life in women with multiple sclerosis. Method A convenience sample of 43 women with multiple sclerosis participated in this quasi-experimental study. They were randomly assigned into 3 groups an existential-spiritual intervention, a cognitive-behavioral intervention, and the control group. Participants were assessed for outcome measures (quality of life and meaning in life) at 3 points in time pretest, posttest, and 5-months follow-up. The Multiple Sclerosis Quality of Life-54 (MSQOL-54) and the Meaning in Life Questionnaires (MLQ) were used as outcome measures. To compare outcomes among the study groups, repeated measures analysis of variance was performed. Results The results showed that while no difference wasistential-spiritual intervention resulted in more positive improvements in some aspects of meaning in life and quality of life.Objective Road traffic injuries are leading cause of death and economic losses, particularly in developing countries such as Iran. Thus, increased understanding of the causes of traffic accidents can help solve this problem. The primary goal of this study was to examine attentional bias, decision-making styles, and impulsiveness in drivers with safe or risky driving behaviors. The secondary purpose was to determine the variance of each variable among 2 groups of drivers. Method This was a cross sectional design study, in which 120 male drivers aged 20-30 years (60 males with risky driving behaviors and 60 with safe driving behaviors) were recruited from Tehran using sampling technique. Barratt Impulsiveness Scale (BIS), Decision-Making Style Scale (DMSQ), Manchester Driver Behavior Questionnaire (MDBQ), Self-Assessment Manikin Scale (SAM), and Dot Probe Task were used. The analyses were performed using IBM SPSS version 22. Results The mean age of participants was 26 years. Significant differences were found between impulsiveness (attentional, motor, and non planning impulsiveness) and decision-making styles (spontaneous and avoidant) between the 2 groups. Also, based on the results of discriminant function analysis (DFS), the subscales of impulsiveness and 2 decision-making styles explained 25% of the variance in the 2 groups of risky and safe drivers. Conclusion Findings of this study indicated that impulsiveness and 2 decision-making styles were predominant factors. Therefore, not only is there a need for research to reduce traffic accidents, but studies can also be helpful in issuing driving licenses to individuals.Objective Suicide is a preventable social harm in the field of health. The present study aimed to design a prediction model for suicide incidence based on Box-Jenkins model in Ilam province. Method Using a retrospective method all completed and attempted suicide data were collected during 1993-2013. Then, using the autoregressive integrated moving average (ARIMA) model, the time series analysis of the Box-Jenkins model was conducted to predict suicide status in the coming years (2014-2015). Results According to the actual results obtained from the suicide data in 2014, a total of 1078 suicides were recorded and compared to the predicted results, according to the fitted model of the time series, which showed the selected model predicted 931 suicide cases, showing 86% accuracy of prediction. The series' prediction indicated 931 suicides in 2014 with a negative growth rate of 25.3% compared to 2013 and 969 suicide cases in 2015 with a positive growth rate of 3.93% compared to 2014. Conclusion The results of this study showed the designed model provides a high diagnostic value to predict suicide rates. These types of models can help to predict suicide in future and plan to control and prevent suicide attempts.Objective This study aimed to investigate the mediating role of positive and negative affect in the association of perceptions of parental involvement, autonomy support, and warmth with resilience among Adolescents with Addicted Parents. Method In this descriptive-correlational study, 63 Adolescents of Addicted Parents studying in Zahak and Hirman, located in Sistan and Baluchestan Province in Iran, were selected using convenience sampling method. The participants completed the questionnaires on perceptions of parenting styles, resilience, and positive and negative affect. see more Data were analyzed via the correlation coefficient and path analysis. Results The results showed that the adolescents' perceived parenting styles were directly and significantly related to positive affect and resilience (P less then 0.01). Moreover, the results of the path analysis indicated that mediated by positive affect, the adolescents' perceived parenting styles predicted resilience indirectly (P less then 0.01). Conclusion Given the results of this study, perceived parenting styles can directly and indirectly predict resilience. It can be concluded that adolescents' perceived parenting styles can enhance resilience among them through promoting positive affect.
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