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Significant improvement in all clinical parameters was achieved at T
and was maintained for up to 10 years (T
), with P < .01 for each parameter. At T
, treatment effectiveness was perceived as excellent by 56% and as good by 26.5% of subjects, while 10.7% perceived a moderate improvement, and 6.8% referred a slight improvement or did not have any improvement. see more Only seven individuals required additional treatments after T
.
These findings suggest that the symptomatic management of TMJ DJD achieved in the short or medium term with a cycle of arthrocentesis and viscosupplementation was effectively maintained in the long term.
These findings suggest that the symptomatic management of TMJ DJD achieved in the short or medium term with a cycle of arthrocentesis and viscosupplementation was effectively maintained in the long term.
To determine the relationship between hormonal contraceptive (HC) use and painful symptoms, particularly those associated with headache and painful temporomandibular disorders (TMD).
Data from the Orofacial Pain Prospective Evaluation and Risk Assessment (OPPERA) prospective cohort study were used. During the 2.5-year median follow-up period, quarterly health update (QHU) questionnaires were completed by 1,475 women aged 18 to 44 years who did not have TMD, menopause, hysterectomy, or hormone replacement therapy use at baseline. QHU questionnaires evaluated HC use, symptoms of headache and TMD, and pain of ≥ 1 day duration in 12 body regions. Participants who developed TMD symptoms were examined to classify clinical TMD. Headache symptoms were classified based on the International Classification of Headache Disorders 3 (ICHD-3). Associations between HC use and pain symptoms were analyzed using generalized estimating equations and Cox models.
HC use, endorsed in 33.7% of QHU questionnaires, was significantly associated with concurrent symptoms of TMD (odds ratio [OR] 1.20, 95% CI 1.06 to 1.35) and headache (OR 1.26, 95% CI 1.11 to 1.43). HC use was also significantly associated with concurrent pain of ≥ 1 day duration in the head (OR 1.38, 95% CI 1.16 to 1.63), face (OR 1.44, 95% CI 1.13 to 1.83), and legs (OR 1.22, 95% CI 1.01 to 1.47), but not elsewhere. Initiation of HC use was associated with increased odds of subsequent TMD symptoms (OR 1.37, 95% CI 1.13 to 1.66) and pain of ≥ 1 day in the head (OR 1.37, 95% CI 1.01 to 1.85). Discontinuing HC use was associated with lower odds of subsequent headache (OR 0.82, 95% CI 0.67 to 0.99). HC use was not significantly associated with subsequent onset of examiner-classified TMD.
These findings imply that HC influences craniofacial pain, and that this pain diminishes after cessation of HC use.
These findings imply that HC influences craniofacial pain, and that this pain diminishes after cessation of HC use.
To test the hypothesis that, in comparison with control, experimental noxious stimulation of the right masseter muscle would result in significant changes in the firing rates, thresholds, and recruitment orders of single-motor units (SMUs) of the nonpainful, synergistic right anterior temporalis muscle during goal-directed isometric biting task performance.
Twenty healthy volunteers received an infusion of hypertonic saline (HS; 5% sodium chloride) into the right masseter to produce pain intensity of 40 to 60 on a 100-mm visual analog scale (VAS). Isotonic saline (IS) infusion was a control. Standardized biting tasks were performed with an intraoral force transducer, and intramuscular electromyographic activity was recorded from the right anterior temporalis muscle. Tasks (slow and fast ramp biting tasks, two-step biting task) were performed in 3 blocks baseline, HS infusion, and IS infusion. Across blocks, SMU thresholds and firing rates were statistically compared, and SMU recruitment sequences were quaes of individual SMUs in the nonpainful synergistic muscles.The global pandemic of COVID-19 poses a huge threat to the health and lives of people all over the world, and brings unprecedented pressure to the medical system. We need to establish a practical method to improve the efficiency of treatment and optimize the allocation of medical resources. Due to the influx of a large number of patients into the hospital and the running of medical resources, blood routine test became the only possible check while COVID-19 patients first go to a fever clinic in a community hospital. This study aims to establish an efficient method to identify key indicators from initial blood routine test results for COVID-19 severity prediction. We determined that age is a key indicator for severity predicting of COVID-19, with an accuracy of 0.77 and an AUC of 0.92. In order to improve the accuracy of prediction, we proposed a Multi Criteria Decision Making (MCDM) algorithm, which combines the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) and Naïve Bayes (NB) classifier, to further select effective indicators from patients' initial blood test results. The MCDM algorithm selected 3 dominant feature subsets Age, WBC, LYMC, NEUT with a selection rate of 44%, Age, NEUT, LYMC with a selection rate of 38%, and Age, WBC, LYMC with a selection rate of 9%. Using these feature subsets, the optimized prediction model could achieve an accuracy of 0.82 and an AUC of 0.93. These results indicated that Age, WBC, LYMC, NEUT were the key factors for COVID-19 severity prediction. Using age and the indicators selected by the MCDM algorithm from initial blood routine test results can effectively predict the severity of COVID-19. Our research could not only help medical workers identify patients with severe COVID-19 at an early stage, but also help doctors understand the pathogenesis of COVID-19 through key indicators.In current research, the hydraulic performance prediction and optimization of an engine cooling water pump was conducted by computational fluid dynamic (CFD) analysis. Through CFD simulation, the pump head, shaft power and efficiency for the original pump at volume flow rate 25 L/min and impeller rotating speed 4231 r/min were 3.87 m, 66.7 W and 23.09% respectively. For improving hydraulic performance, an optimization study was carried out. After optimization, four potential optimized designs were put forward. The efficiency of the optimized design No.1 for engine cooling water pump was nearly 6% higher than that of the original pump model; and the head of the optimized design No.2 for engine cooling water pump was 9% higher than that of the original pump model. Under the condition of maintaining the pump head and considering comprehensive improvement effect, the optimized design No.3 was considered as the best design and selected as the test case for validating the optimum design. The hydraulic performance predictions for this optimum engine cooling water pump agreed well with experimental data at design condition with relative discrepancies of 2.
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