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Gastrointestinal diseases account for significant morbidity and mortality across the world. The study aims at establishing the epidemiological profile of gastrointestinal diseases in a Nigerian tertiary care center.
This is a descriptive retrospective study of all gastrointestinal specimens, submitted to the histopathology department of Delta State University Teaching Hospital (DELSUTH) for diagnosis. The age, sex, and histological diagnosis were extracted from the archives of the department. click here These were re-reclassified into diagnostic groups, analyzed using Excel spread sheet 2007 and summarized in tables.
The study involves 570 patients (290 males and 280 females) with gastrointestinal tract (GIT) diseases within the age range of 10 days to 99 years, and of a mean age of 48.4 years. Congenital, inflammatory, benign neoplasms, malignant neoplasms and vascular diseases accounted for 1.6%, 77.5%, 2.6%, 18.1% and 0.18% of the cases respectively. These lesions were domiciled in the esophagus (1.4%), stomachGIT cancers (colorectal and gastric cancer) being the next most common. The preponderance of GIT lesions among the productive age calls for action to ameliorate the trend. Preventive public enlightenment campaign on GIT cancer risk factors and population-based screening programmes especially for Helicobacter pylori infection and colorectal cancer is highly recommended.
To understand factors related to cervical cancer screening behaviors and factors that influence these behaviors among women living in Eswatini.
Data from the World Health Organization STEP's data - A household cross sectional survey in Eswatini in 2014 for 1217 eligible women aged 15 and above. The dependent variable was binary categorized, into two levels With or without cervical cancer screening experience and independent variables were factors related to cervical cancer screening. The binary logistic regression models were used to analyze the factors related to cervical cancer screening.
Women with cervical cancer screening experience were 15.2%. The multiple logistic regression analysis revealed that women's age, education, employment status, history of cardiovascular disease and community environment were significantly correlated with the cervical cancer screening behavior.
Screening for cervical cancer is still low among women living in Eswatini. Our findings provide a greater understanding of African women's factors related to cervical cancer screening among African countries which are age, education, employment status and environmental issues. This can particularly be attributed to the limited availability and accessibility of cervical cancer screening services among socio-economically disadvantaged populations.
Screening for cervical cancer is still low among women living in Eswatini. Our findings provide a greater understanding of African women's factors related to cervical cancer screening among African countries which are age, education, employment status and environmental issues. This can particularly be attributed to the limited availability and accessibility of cervical cancer screening services among socio-economically disadvantaged populations.
Failure of radioactive iodine therapy (RAI) in patients with hyperthyroidism is not uncommon. A Second dose is usually needed if the first one failed. The purpose of this audit was to determine the efficacy of RAI in patients with hyperthyroidism at Groote Schuur Hospital (GSH).
This was a retrospective study. A single observer reviewed the records of all patients who received I131 therapy for hyperthyroidism between 23rd April, 2010 and 23rd November, 2017 in conjunction with their pre- and post-treatment thyroid function tests. Results of their thyroid ultrasound were retrieved and documented. The images of their Tc99m sodium per-technetate thyroid scans were also retrieved and reprocessed. Cure was determined by three consecutive thyroid function tests by euthyroid or hypothyroid status 6 months after therapy.
Of the 353 patients with complete records, 310 (88%) of our patients were females and 43 (12%) were male patients. Majority (200 patients) of the patients were older than 45 years of age, 148 poiodine therapy be considered before second RAI.
Our audit showed cure rate was 68% at 6 month and 89% at a year. A second dose was indicated in 32% of patients. Patients presenting with severe thyrotoxicity are likely to require more than one RAI therapy. Further researches are suggested to find out if pre-treatment with antithyroid drugs would influence efficacy of RAI in patients with severe thyrotoxicity and would a one year follow up after radioiodine therapy be considered before second RAI.
Due to the prevailing socio-cultural and religious affiliations, Paediatricians in sub-Saharan Africa face unique ethical dilemmas. An understanding and application of the ethical principles can help prevent and resolve these dilemmas, and improve child health indices. The objective is to determine the knowledge, attitude and practical applications of non-maleficence and beneficence by child-care doctors at a Teaching Hospital.
This is a questionnaire-based study. Socio-demographics, knowledge and attitude towards the ethical principles, and its utilisation by doctors in childcare was sought. Data were analyzed using descriptive statistics.
294 doctors participated. The mean percentage knowledge score of nonmaleficence and beneficence was 31.00±21.14, significantly higher among doctors in Paediatrics (39.35±23.44, p=0.0001). For every decrease in professional rank, knowledge score decreased by 3.8224 (95% CI -5.824 - -1.819; p=0.0001). The doctors had a high mean percentage score on attitude towards ethics of 74.79±16.34, and for every increase in years of practice, attitude towards ethics score would increase by 2.922 (95% CI 1.133 to 4.711, p=0.001). There was a low practice score of 34.27±20.07. Majority (69%) encountered less than one dilemma a month. More than 90% of doctors had encountered dilemmas involving the principle of non-maleficence [184 (90.6%)], while 154 (75.9%) involved beneficence.
Most respondents have a low level of knowledge and practice of the principles of nonmaleficence and beneficence. Their excellent attitude implies their willingness at improving their knowledge and practice.
Most respondents have a low level of knowledge and practice of the principles of nonmaleficence and beneficence. Their excellent attitude implies their willingness at improving their knowledge and practice.
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