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Introduction High prevalence of musculoskeletal disorders (MSDs) have been reported among operators in dentistry related to prolonged demanding and awkward operative tasks, in which non-neutral vertebral positions and risky joint articulations are adopted. The aim of the study was to investigate the feasibility and reliability of the application of the Rapid Entire Body Assessment (REBA) among dental students utilising three digital photographs of the operator to determine chairside ergonomic risk.Materials and methods Third-year dental students (n = 28) obtained profile, back and frontal digital photographs of student operators in a clinical session. REBA scorings were assigned per student utilising the photographs by student groups and independently by a physiotherapist. MLN8054 research buy Statistical comparisons were done for both scorings.Results There was substantial interrater reliability (kappa = 0.625; p less then 0.001) and moderate concordance level (Kendall's Tau-b of 0.568; p less then 0.01) between the scores derived from students and staff. Medium- and high-risk students based on the REBA scores accounted for 64% and 75% of the class as determined by students and staff, respectively.Discussion The high percentage of medium-to-high-risk REBA values matched the prevalence of MSDs reported by dental students in the literature. Compared to staff, students with moderate reliability were able to produce REBA scores adequately.Conclusion REBA utilising digital photographs may be an easily applicable and moderately reliable tool for alerting static ergonomic risk for clinical dental students. Modification of at-risk behaviour early in training may limit the establishment of bad posture habits and aid in the prevention of MSDs during their clinical years and post-graduation.Introduction The General Data Protection Regulation (GDPR) is now at the core of data protection and provides more rights than ever before for individuals to control the data that is held about them, and holds organisations accountable.Materials and methods Questionnaire-based knowledge audit consisting of 18 questions relating to GDPR, which was created and distributed to all staff at departmental audit meetings. The gold standard was set that all members of staff were required to pass the questionnaire, with the pass mark set at 14/18. This was followed by a tailored teaching session in conjunction with an online delivery element.Results Cycle 1 was completed in December 2018; the pass rate was 1.6% (1/63) with a response rate of 87.5% (63/72). Scores ranged from 5-14 out of 18. Following dissemination of results, a tailored teaching session was conducted in conjunction with online learning. Cycle 2 was completed in February 2019; the pass rate was 83.9% (47/56) with a response rate of 77.7% (56/72). Scores ranged from 3-18 out of 18.Conclusions Initially, staff knowledge of GDPR was inadequate. Staff knowledge improved with tailored teaching; however, knowledge and understanding of GDPR requires further improvement to meet the gold standard. Therefore, repeat cycles of tailored teaching and audit are planned. It is important that all staff have a good understanding and working knowledge of GDPR to ensure compliance in all areas of practice.Objectives To explore the level and nature of dental care provided by dental hygienists and therapists to older adults (65 and over) and to identify barriers to such care.Methods An online survey of all GDC-registered hygienists and therapists in Scotland.Results Thirty-two percent (196 of 609) responded. Seventy-five percent worked in general dental practice. Nearly two-thirds of the workload of those in general dental practice was with older patients. Most reported that numbers of such patients were increasing. Fifty-seven percent worked to inflexible appointment slots of 15 or 30 minutes. Time pressure, consent to treatment and power of attorney were the worst administrative problems in the workplace.Only one in four, mainly Public Dental Service (PDS) employees, provided domiciliary care or treated patients in care homes. Common problems in these settings were poor hygiene, communicating with patients, capacity to consent, power of attorney, insufficient training and time, poor staff liaison, lack of supp effectively and economically by developing such 'mid-level' clinical roles in new models of dental care.Childhood maltreatment is associated with cognitive deficits that in turn have been predictive for therapeutic outcome in psychiatric patients. However, previous studies have either investigated maltreatment associations with single cognitive domains or failed to adequately control for confounders such as depression, socioeconomic environment, and genetic predisposition. We aimed to isolate the relationship between childhood maltreatment and dysfunction in diverse cognitive domains, while estimating the contribution of potential confounders to this relationship, and to investigate gene-environment interactions. We included 547 depressive disorder and 670 healthy control participants (mean age 34.7 years, SD = 13.2). Cognitive functioning was assessed for the domains of working memory, executive functioning, processing speed, attention, memory, and verbal intelligence using neuropsychological tests. Childhood maltreatment and parental education were assessed using self-reports, and psychiatric diagnosis was ba related cognitive preconditions, might enhance response to therapeutic treatments.CD19-CAR T-cell therapy (CART19) causes B-cell aplasia (BCA) and dysgammaglobulinemia but there is a lack of information about the degree of its secondary immunodeficiency. We conducted a prospective study in children and young adults with acute lymphoblastic leukaemia treated with CART19, analysing the kinetics of BCA and dysgammaglobulinemia during therapy, as well as the B-cell reconstitution in those with CART19 loss. Thirty-four patients were included (14 female) with a median age at CART19 infusion of 8.7 years (2.9-24.9). Median follow-up after infusion was 7.1 months (0.5-42). BCA was observed 7 days after infusion (3-8), with persistence at 24 months in 60% of patients. All patients developed a progressive decrease in IgM and IgA 71% had undetectable IgM levels at 71 days (41-99) and 13% undetectable IgA levels at 185 days (11-308). Three of 12 patients had protective levels of IgA in saliva. In two of three patients who lost CART19, persistent B-cell dysfunction was observed. No severe infections occurred.
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