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Addictive disorders are a serious health problem to which large amounts of research resources are devoted. This study aims to analyze the evolution and scientific impact of the publications derived from the funding of research projects by the Spanish National Plan on Drugs (PNSD). The list of grants awarded was provided by the PNSD. Derived publications were obtained by asking the principal investigators of the grants and searching in the Web of Science and Scopus. Bibliometric indicators and evolutive trends of scientific production per project were calculated. On average, the PNSD conferred 15 annual grants to research projects, with an annual amount close to one million euros (€944,200.64) and an average amount per grant of just over €60,000, being higher in basic research and in alcohol. 71,9% of the grants had derived publications and almost half of them produced between one and three publications, with basic research being the most prolific. The international journal in which most articles were published was Psychopharmacology (50) and among Spanish journals, Adicciones stood out (28). A high level of co-authorship and international collaboration was identified. Most of the PNSD-funded projects produced research articles, many of them in journals belonging to the first and second quartiles of the Journal Citation Reports. The results of this study have revealed the scientific impact of the PNSD research projects funding and may contribute to determining future funding priorities.Although correct diagnosis and management of patients with schizophrenia and a comorbid substance use disorder (SUD) would determine a decrease in morbidity and mortality in these patients, development of efficient therapeutic strategies is still pending. We present recommendations on the pharmacological and psychological management of these patients following the 'PICO' structure (Patient-Intervention-Comparison-Outcomes). Evaluation of the quality of studies and summary of the evidence for each question was performed following the recommendations of the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) working group. Our results suggest 1) In patients with schizophrenia and cannabis use disorder, it is not possible to recommend one antipsychotic drug over another (between olanzapine, risperidone or haloperidol) for improving psychotic symptoms, reducing cannabis use, or improving pragmatic variables (weak recommendation). Clozapine cannot be recommended to reduce cannabis use (weak recommendation). 2) In patients with schizophrenia and cocaine use disorder we recommend haloperidol over olanzapine to reduce craving (moderate recommendation), and olanzapine over haloperidol to improve motor side effects in these patients (moderate recommendation). 3) In patients with schizophrenia and alcohol use disorder while naltrexone is recommended to reduce alcohol use (in terms of reducing alcohol craving) (weak recommendation), there is insufficient evidence to make any recommendation on the use of adjuvant acamprosate (weak recommendation). 4) In patients with schizophrenia and nicotine use disorder, adjuvant bupropion and varenicline are recommended for reducing nicotine use and nicotine abstinence (strong/moderate recommendation). 5) In patients with schizophrenia and polydrug use disorder, second-generation over first-generation antipsychotic drugs and olanzapine over other second-generation antipsychotics are recommended to improve psychotic symptoms (moderate/weak recommendation).Traditionally, psychopathy research has focused on assessing men with the Psychopathy Checklist Revised (PCL-R). Research on women with other assessment tools is scarce. The objective of this study is to evaluate psychopathy, using various tools, in a sample with both women and men. The study involved 204 inmates (mean age (DS) = 40.93 (11.8)), 28 women (13.7%), in the Pereiro de Aguiar penitentiary (Ourense). Sociodemographic, substance use, and criminal variables were collected, and all were evaluated with the following tools PCL-R, Comprehensive Assessment of Psychopathic Personality (CAPP), and the International Personality Disorder Examination. In this sample, when assessed with the PCL-R, males obtained significantly higher scores on facet 4, which measures antisocial behaviour. Women obtained significantly higher scores on the Self domain in the CAPP, measuring narcissism. No symptom or item was able to clearly discriminate psychopathic women from psychopathic men in a Support Vector Machine model. The construct of psychopathy is similar for women and men in this representative penitentiary sample. Women showed higher scores for narcissism and men for antisociality. It is better to combine the PCL-R with another tool such as the CAPP to assess these psychopathological differences. No symptom or item has a score that can be recommended as a method for discriminating psychopathic women from psychopathic men.The objective of the study was to analyze the relationship between individual socioeconomic characteristics and cigarette consumption in Spain. The sample consisted of 19,931 individuals aged 15 or older who completed the European Health Interview Survey for Spain (EHSS-2014). Variables prevalence and intensity of cigarette consumption. Multivariate ordered logistic regression analysis was performed with the following socioeconomic variables social classes, educational attainment, main activity, economic situation and, for the working population, the activity sector. Other control variables were sociodemographic variables and healthy lifestyle habits (physical exercise, diet and alcohol consumption). Bemnifosbuvir The factors that relate to greater prevalence are lower social class, not having university studies, being unemployed, having worse economic situation and working in hospitality industry. On the other hand, the variables related to higher intensity of cigarette consumption of the smoking population are lower social class, not having university studies, and being neither a student nor on a permanent contract. Regarding control variables, those regressors associated with a higher prevalence and intensity of cigarette consumption are being male, being aged between 36 and 65, being divorced, having fewer children at home and having worse lifestyle habits.
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