Notes

Baby growth stops because the initial locating regarding preeclampsia is a clinical predictor associated with mother's and neonatal prognoses: a new single-center retrospective study.
Indeed, we identify several known and novel glycan-mediated ligands of galectin-1 as well as validate that galectin-1 binds the native CD44 glycoprotein in a glycan-mediated manner.
CNS relapse in patients with LDCGB is a poor prognosis event. The incidence of relapse is variable according to the literature. Data in Latin America is lacking.

In order to establish the incidence of CNS relapse in our cohort, time to CNS relapse and the impact of CNS relapse risk factors, a retrospective cohort study was performed, from January 2012 to June 2017.

One hundred and forty seven patients were analyzed. The median age was 66 years (ICR 56-76); 76 patients (51.70%) were men. The IPI was low or intermediate/low in 115 (78.2%) cases. The CNS IPI was intermediate in 77 (52.4%) and high in 14 (9.5%) of cases. Thirty-five (23.81%) patients received intrathecal prophylaxis. No patient received systemic prophylaxis. During the follow-up, 8 (4.59%) patients had CNS relapse, none of them with high IPI. The median time to relapse was 6.5 months (ICR 5.5-10). Seven (87.5%) patients relapsed within the year of diagnosis. We found no risk factors for CNS involvement in the bivariate analysis. The incidence of relapse was 2.7% (CI 0.2% -4.6%), 4.8% (CI 1.8% -8.9%) and 5.4% (CI 4.5- 8.9%) at 6, 12 and 24 months, respectively.

The incidence of CNS relapse was similar to that described in the international series. Our study confirms that the majority of patients relapse during the first year of follow up. We must carry out broader collaborative work to better establish the risk factor for CNS relapse.
The incidence of CNS relapse was similar to that described in the international series. Our study confirms that the majority of patients relapse during the first year of follow up. We must carry out broader collaborative work to better establish the risk factor for CNS relapse.Invasive mechanical ventilation (VMI) is a life support therapy that is not free of complications, such as ventilator induced diaphragmatic dysfunction, which is characterized by atrophy and weakness of the muscle. Interest in this pathology seems to be based on the association found with negative clinical results. The prevalence ranges between 29 and 80%, probably due to the variability between the different diagnostic methods and the time of evaluation. The gold standard continues to be the transdiaphragmatic negative pressure generated by the bilateral stimulation of the phrenic nerves, although due to the lack of practicality, diaphragmatic ultrasound began to be used. Although it has several modalities, not all of them have correlation analysis with the gold standard. Another problem arises when analyzing the independent association between pathology and VMI, since confusing factors are not easy to isolate.Squamous cell carcinoma of the tongue is the most common malignant tumor of the oral cavity. The finding of metastases, in this type of cancer, is considered the main factor of poor prognosis with a marked effect on the overall survival. The normal progression tends to be locoregional, at the surgical site or regional lymph nodes, and systemic involvement is usually uncommon. We present the case of a male patient, 40 years old, with tongue cancer and bilateral kidney metastases, eleven months after initial diagnosis. The aggressive biology, the extremely rare metastases location and a grim prognosis, illustrate an unusual case, which highlights the importance of its publication.
Chronic Obstructive Pulmonary Disease (COPD), a preventable and underdiagnosed pathology, can be defined as a progressive and poorly reversible limitation to airflow as a result of a persistent inflammatory response due to inhalation of harmful substances, particularly tobacco smoke. The disease has a systemic impact. Among other conditions, it may increase the risk of cognitive impairment along with its associated consequences.

Prospective, cross-sectional, observational and analytical design. Picrotoxin cell line The space were COPD patients who visited in two health institutions from June 2017 to September 2018. Non-probabilistic and convenience sampling. Data were collected on demographics, tobacco consumption, comorbidities (Charlson index), a validated scale for dyspnea (MCRm), the main symptom in COPD and the COPD Assessment Test (CAT) were applied along with a history of exacerbation of the disease. The severity of COPD was evaluated by spirometry according to GOLD guideline. Cognitive impairment was assessed using Net.
This study describes the knowledge and perceptions regarding colorectal cancer screening (CRC) in a population of teachers from primary and secondary schools in Carcarañá, Santa Fe. The proportion of participants who underwent the screening is described, as well as the facilitating factors and barriers that could affect test adherence.

An observational, descriptive and cross-sectional study was carried out through a self-administered survey of the population of teachers aged 50 or over from all primary and secondary schools in the city.

96 teachers, 87 women (90.6%) and 9 men (9.4%) were surveyed. Average age 53.2 ± 2.5 years. 66.7% knew about CRC screening. However, only 13.5% knew the recommended time to start performing these tests. 28.1% had adhered to some of the screening tests. 94.8% agreed that CRC has a greater chance of cure if it is discovered early, and 92.7% reported that screening is part of good health care. .

The positive perception regarding screening is not consistent with adherence to screening. Lack of knowledge, lack of information and medical indication are the most important barriers to adherence. The main facilitating factor was the existence of a family history of CRC. New research that addresses this issue would be necessary in order to develop strategies aimed at modifying these barriers and reducing mortality from this neoplasm
The positive perception regarding screening is not consistent with adherence to screening. Lack of knowledge, lack of information and medical indication are the most important barriers to adherence. The main facilitating factor was the existence of a family history of CRC. New research that addresses this issue would be necessary in order to develop strategies aimed at modifying these barriers and reducing mortality from this neoplasm
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