Notes

Target-driven supramolecular self-assembly for frugal amyloid-β photooxygenation towards Alzheimer's.
vegetables form a major component of the human diet. However, poor agronomic practices may put consumers at risk of parasitic infections. This study evaluated the parasitic contamination of vegetables grown in selected farms in Ibadan, Nigeria.

Two hundred and eighty vegetable species African eggplant (
), lettuce (
), cucumber (
), spinach (
), white jute (
), pumpkin (
), green pepper (
.), okro (
), quill grass (
), tomato (
) were collected from farms within Ibadan. Samples were washed in water, and the resulting washing solution was filtered and centrifuged to concentrate the parasitic stages. Sediments were examined by iodine and modified Ziehl-Neelsen stained smears technique.

parasites were detected in 14 (5.0%, 95% CI 32.6%-67.3%) of samples. The highest contaminated vegetable was white jute 32.1 (95% CI 17.9%-50.6%), followed by pumpkin 7.1(95% CI 1.9-22.6), quill grass 7.1% (95% CI 1.9-22.6) and lettuce 3.5 (95% CI 0.6-17.7). The commonest parasites were
larvae 42.9 (95% CI 21.3-67.4),
21.4 (95% CI 7.5-47.5),
21.4 (95% CI 21.3-67.4), and
. 14.3 (95% CI 4.0-39.9).

these findings provide evidence of contamination of vegetables from farms in Ibadan with parasites of public health importance. Information on best practices should be designed, packaged and disseminated through appropriate channels to enhance positive behavior change among farmers.
these findings provide evidence of contamination of vegetables from farms in Ibadan with parasites of public health importance. Information on best practices should be designed, packaged and disseminated through appropriate channels to enhance positive behavior change among farmers.Patients with lupus anticoagulants are at high risk of systemic arterial and venous thrombosis and arterial stroke. We present an unusual case of a young man presenting inguinal pain. Doppler ultrasound revealed spermatic vein thrombosis on the left side. Hematologic workup revealed positive lupus anticoagulant. The patient was treated with therapeutic heparin.Primary malignant melanoma of the female genital tract is an extremely rare tumor. It most commonly affects the vulva then the cervix and the vagina. Vulvar cancer accounts for about 1% (all sites) of melanomas. In order of frequency, it occurs in the vagina, uterus and ovary. Less than 200 cases of vulvar cancers have been described worldwide. We here report a clinical case of malignant vulvar melanoma in a 72-year-old postmenopausal woman. Partial hemivulvectomy and bilateral superficial inguinal lymphadenectomy were performed. The postoperative course was favorable and the patient was discharged on postoperative day 15.Most ingested foreign bodies pass spontaneously through the gastrointestinal tract and only 1% of them can perforate or penetrate the wall of stomach and duodenum and migrate into organs, such as the liver and pancreas. We report herein the case of a 59-year-old woman who presented to the emergency department with epigastric pain and fever. Computed tomography of the abdomen revealed a linear foreign body that perforate the posterior wall of the prepyloric region of the stomach. The foreign body was removed laparoscopically in one piece and was identified as a 3-cm-long fish bone. The patient recovered without complications and was discharged on the 4th postoperative day. Pancreatic foreign body is a rare entity and laparoscopic removal is warranted in majority of cases.A 54-year-old female presented with a six year history of increasing abdominal swelling and discomfort and two months of intermittent constipation and difficulty with micturition. She was referred from the gynecological service having been investigated for a pelvic pathology without any positive findings. Her medical history was otherwise unremarkable. Physical examination revealed a non-tender intra-abdominal mass extending from epigastrium to the pelvis with a smooth surface. A large intra-abdominal multi-loculated cyst, separate from the ovaries, was seen on imaging. At laparotomy, the cystic tumour was discovered to arise from the mesentery of the terminal ileum and was resected en bloc. Histopathology revealed the tumour to be a benign mucinous cystadenoma, possibly of ovarian origin. This report aims to raise awareness of the difficulty of distinguishing ovarian from extra-ovarian mucinous cystadenomas on histopathological examination alone.The effect of air-borne nanoparticles (NPs) on human health is an active area of research, with clinical relevance evidenced by the current COVID-19 pandemic. As in vitro models for such studies, lung-on-a-chip (LOAC) devices can represent key physical and physiological aspects of alveolar tissues. However, widespread adoption of the LOAC device for NP testing has been hampered by low intra-laboratory and inter-laboratory reproducibility. To complement ongoing experimental work, we carried out finite-element simulations of the deposition of NPs on the epithelial layer of a well-established LOAC design. We solved the Navier-Stokes equations for the fluid flow in a three-dimensional domain and studied the particle transport using Eulerian advection-diffusion for fine NPs and Lagrangian particle tracking for coarse NPs. Using Langmuir and Frumkin kinetics for surface adsorption and desorption, we investigated NP adsorption under different exercise and breath-holding patterns. Conditions mimicking physical exercise, through changes in air-flow volume and breathing frequency, enhance particle deposition. selleck compound Puff profiles typical of smoking, with breath-holding between inhalation and exhalation, also increase particle deposition per breathing cycle. Lagrangian particle tracking shows Brownian motion and gravitational settling to be two key factors, which may cooperate or compete with each other for different particle sizes. Comparisons are made with experimental data where possible and they show qualitative and semi-quantitative agreement. These results suggest that computer simulations can potentially inform and accelerate the design and application of LOAC devices for analyzing particulate- and microbe-alveolar interactions.
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