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Nude (D) mutant mice carry a absurdity mutation in the homeobox involving Hoxc13.
Genetically, the uncorrected pairwise divergences between the new species and their congeners in the C. siamensis group were between 15.53-28.09%. The new species is currently known only from granitic rocky streams at Wang Mai Pak Waterfall in the Nakhon Si Thammarat mountain range. Its discovery suggests that additional unrecognized species of Cnemaspis may still occur in unexplored areas of southern Thailand.A new genus, Sinogodavaria gen. nov., with two new species, S. multiformis sp. nov. and S. tenebrosa sp. nov., is described from China. It belongs phylogenetically to the Hypocera group of genera. The species Latiborophaga bathmis Liu is transferred to the new genus. A key to species of the new genus is presented.Four species of Minettia Robineau-Desvoidy, 1830 from Southwest China are described as new to science Minettia (Minettiella) dashahensissp. nov., M. (Minettiella) longispinasp. nov., M. (Minettiella) membranaceasp. nov. and M. (Minettiella) zhaotongensissp. nov. A key to the species of the subgenus Minettiella of the world is presented.Mimops orientalis Kraepelin, 1903 is a monotypic species of Mimopidae endemic to China. The species is known only from a single specimen, the holotype. Little is known about its biology, habitat associations, or phylogenetic relationships. It was rediscovered on Qinling Mountain in Shaanxi and Henan provinces, China, 117 years after its last record. Detailed descriptions and colour photographs of living specimens are provided along with its ecology, updated conservation notes, and data on sexual dimorphism. selleckchem A genetic analysis (COI, 16S rRNA, and 28S rRNA) was conducted to assess the phylogenetic relationships among Mimopidae, Cryptopidae, Scolopendridae, Scolopocryptopidae, and Plutoniumidae. The results support classifying Mimopidae as a valid family.Polynoidae Kinberg, 1856 has five branchiate genera Branchipolynoe Pettibone, 1984, Branchinotogluma Pettibone, 1985, Branchiplicatus Pettibone, 1985, Peinaleopolynoe Desbruyères & Laubier, 1988, and Thermopolynoe Miura, 1994, all native to deep-sea, chemosynthetic-based habitats. Of these, Peinaleopolynoe has two accepted species; Peinaleopolynoe sillardi Desbruyères & Laubier, 1988 (Atlantic Ocean) and Peinaleopolynoe santacatalina Pettibone, 1993 (East Pacific Ocean). The goal of this study was to assess the phylogenetic position of Peinaleopolynoe, utilizing DNA sequences from a broad sampling of deep-sea polynoids. Representatives from all five branchiate genera were included, several species of which were sampled from near the type localities; Branchinotogluma sandersi Pettibone, 1985 from the Galápagos Rift (E/V "Nautilus"); Peinaleopolynoe sillardi from organic remains in the Atlantic Ocean; Peinaleopolynoe santacatalina from a whalefall off southern California (R/V "Western Flyer") and Thermopolynoe is required. We apply the subfamily name Lepidonotopodinae Pettibone 1983, for the clade comprised of Branchipolynoe, Branchinotogluma, Bathykurila, Branchiplicatus, Lepidonotopodium, Levensteiniella Pettibone, 1985, Thermopolynoe, and Peinaleopolynoe.The megascolecid earthworms of the Phu Quoc island are intensively investigated. Twelve species in three genera (Lampito Kinberg, 1867, Amynthas Kinberg, 1867, and Metaphire Sims & Easton, 1972) are recorded. Of these, Metaphire doiphamon Bantaowong & Panha, 2016 is recorded for the first time in Vietnam, and three species are newly described, namely Amynthas catenatus sp. nov., A. phuquocensis sp. nov., and A. poropapillatus sp. nov. An identification key to 12 megascolecid species is provided as well.[This corrects the article DOI 10.1177/1179573519899471.].Background Bacteremia and sepsis are significant contributors to the morbidity, mortality, and economic burden of health care systems worldwide. Procalcitonin has been identified as a potentially useful marker of disease and severity in sepsis. However, the assumption that greater procalcitonin levels correlate with greater burden of disease has not been adequately studied. Methods A retrospective chart review of adult patients admitted to an urban teaching hospital with suspected sepsis was undertaken to test the association of elevated procalcitonin (>30 ng/mL) with other markers of sepsis (lactic acid, white blood cell count, percent bands), severity of disease (Sequential Organ Failure Assessment [SOFA] and Acute Physiology and Chronic Health Evaluation-II [APACHE II] scores), and mortality. Results In total, 168 patients were identified over 18 months (42% ward, 11% Stepdown, 44% medical intensive care unit [MICU], 2% surgical intensive care unit (STICU), 1% gynecology [GYN]). The Spearman correlation analysis showed that serum procalcitonin level did not correlate with SOFA (P = .238) or APACHE II (P = .918) scores on admission, and did not correlate with survival (Kruskal-Wallis test, P = .937). However, higher serum procalcitonin levels were associated with patients who had positive blood cultures (Kruskal-Wallis test, P = .0016 for Gram-positive and P = .0007 for Gram-negative bacteria). Lactic acid levels on admission strongly correlated with SOFA APACHE II (the Spearman correlation, P 30 ng/mL do not appear to correlate with the severity of disease in a sample of patients with markedly elevated initial procalcitonin levels.Introduction Considering limited data about the association between smoking and primary systemic vasculitides (PSV), present study aims to investigate smoking habit in PSV patients compared to healthy subjects as well as to examine the effect of smoking on clinical characteristics, disease activity and disease outcome in PSV patients. Methodology We included 126 patients diagnosed with PSV and 210 age- and sex-matched healthy controls. Demographic and clinical information and smoking history of patients and healthy controls were obtained by direct interview and questionnaire. Individuals who had smoked at least 100 cigarettes in their lifetime before the first symptom of vasculitis were classified as smokers; those who had never smoked or smoked less than 100 cigarettes in their lifetime were categorized as never smokers. Disease activity was evaluated by Birmingham Vasculitis Activity Score (BVAS). Disease outcome was assessed by vasculitis damage index (VDI) and the number of patients with disease in remission.
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