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Incidence regarding over weight along with obesity and their linked components between well being sciences college students, Saudi Persia.
Background Postoperative infection is one of the most prevalent complications following total joint arthroplasty (TJA). As such procedures become more prevalent, it is imperative that we develop new prophylactic methods to prevent the need for revision procedures. In recent years, surgeons have opted to use antibiotic-loaded bone cement (ALBC) rather than plain bone cement (PBC) in primary hip and knee replacements due to its theoretical potential of lowering infection rates. However, the cost-effectiveness of this intervention remains in question.Questions/Purposes To determine the rate of infection and cost-effectiveness of antibiotic-loaded bone cement as compared to plain bone cement in hip and knee arthroplasty. Patients and methods We reviewed 4116 primary hip and knee arthroplasty cases performed between 2016 and 2018 at Morristown Medical Center in New Jersey. Data regarding demographics, complications, and any readmissions due to deep infection were collected retrospectively. During that time period costs in order to increase quality and efficiency. We estimate that our hospital system could save nearly $120,000/year by using plain bone cement instead of antibiotic-loaded cement. Published by Elsevier B.V. on behalf of Professor P K Surendran Memorial Education Foundation.Background The purpose of this study was to determine whether intramedullary administration of extended-release minocycline microspheres would affect osseointegration. Methods Twenty-two rats were randomized to minocycline or saline femoral intramedullary injection followed by implantation of titanium alloy rods. Following euthanasia at four-weeks, pushout testing was performed and bone-volume-fraction assessed. Results Pushout strength was marginally greater in minocycline-treated implants (122.5 ± 39.1 N) compared to saline (96.9 ± 26.1 N) (P = 0.098). No difference was observed in energy to maximum load, mean stiffness, or peri-implant bone-volume-fraction (P > 0.05). Conclusions Peri-implant minocycline administration did not impair implant fixation strength or peri-implant bone-volume, supporting its potential utility as an adjunct to intramedullary implants. © 2019 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.Ensuring responsible production and consumption is one of the United Nations' Sustainable Development Goals (SDGs) to which the European Union (EU) has committed. An increasing body of literature has demonstrated that global trade flows are key contributors to the environmental impacts of consumption. Indeed, very often developed countries import fuels and other resources from developing ones, displacing a large share of environmental burdens related to consumption of goods outside their boundaries. This paper has a triple goal. Firstly, it assesses the environmental impacts of traded goods with a bottom-up approach, adopting life cycle assessment (LCA) and identifying hotspots related to EU consumption. Secondly, it analyses the extent to which the trade of goods is contributing to the environmental impacts of EU apparent consumption. Finally, it compares the contribution of environmental impact of EU traded goods against overall global impacts. Forty representative products imported or exported by the EU were selected based on their relevance in mass and economic value according to official trade statistics. LCA was applied to these products using the EU Environmental Footprint method. FK228 The results were then upscaled in order to be representative of the entire impact of traded goods in the EU. Overall, consumption in the EU resulted to cause considerable environmental impacts outside EU boundaries and impacts of imports and exports were mostly associated with few products groups, which either were traded in large quantities (e.g. "Fuels and mineral oils") or had a high impact intensity compared to the others (e.g. "Pulp of wood and other cellulosic material" for land use). © 2019 The Authors.An estimated 3.3 million people are living with a traumatic brain injury (TBI)-associated morbidity. Currently, only invasive and sacrificial methods exist to study neurochemical alterations following TBI. Nuclear magnetic resonance methods-magnetic resonance imaging (MRI) and spectroscopy (MRS)-are powerful tools which may be used non-invasively to diagnose a range of medical issues. These methods can be utilized to explore brain functionality, connectivity, and biochemistry. Unfortunately, many of the commonly studied brain metabolites (e.g., N-acetyl-aspartate, choline, creatine) remain relatively stable following mild to moderate TBI and may not be suitable for longitudinal assessment of injury severity and location. Therefore, a critical need exists to investigate alternative biomarkers of TBI, such as acrolein. Acrolein is a byproduct of lipid peroxidation and accumulates following damage to neuronal tissue. Acrolein has been shown to increase in post-mortem rat brain tissue following TBI. However, no methods exist to noninvasively quantify acrolein in vivo. Currently, we have characterized the T1 and T2 of acrolein via NMR saturation recovery and Carr-Purcell-Meiboom-Gill experiments, accordingly, to maximize the signal-to-noise ratio of acrolein obtained with MRS. Additionally, we have quantified acrolein in water and whole-brain phantom using PRESS MRS and standard post-processing methods. With this potential novel biomarker for assessing TBI, we can investigate methods for predicting acute and chronic neurological dysfunction in humans and animal models. By quantifying and localizing acrolein with MRS, and investigating neurological outcomes associated with in vivo measures, patient-specific interventions could be developed to decrease TBI-associated morbidity and improve quality of life.Educational activities and training opportunities in toxicologic pathology are major goals of 9 formally established Toxicologic Pathology Societies and the International Academy of Toxicologic Pathology. Some Toxicologic Pathology Societies have examination-based certification programs while others accept certification or registration by veterinary pathology organizations including the American College of Veterinary Pathologists, the European College of Veterinary Pathologists. We summarize here the membership numbers and current activities of formally established Toxicologic Pathology Socities. ©2020 The Japanese Society of Toxicologic Pathology.
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