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A draft report by the International Commission on Radiation Units and Measurements (ICRU) Report Committee 26 (RC 26) will recommend alternative definitions of the operational quantities that are better estimators of radiation protection quantities. Dose coefficients for use with physical field quantities - fluence and, for photons, air kerma - are given for various particle types over a broad energy range. For the skin dosimetry, several changes are of particular interest. Specifically, the use of absorbed dose instead of dose equivalent has been selected as the operational quantity since deterministic effects are of primary interest in the skin. In addition, newly recommended phantoms are specified for computing the operational dose coefficients. The report also addresses computational approaches such as tally volumes, depths, source areas, and rotational angles. In this work, dose coefficients calculated for the local skin in support of the ICRU report are presented. Energy-dependent dose coefficients wereRP by IOP Publishing Limited. All rights reserved.Modified hybrid structures of TiO2 nanotubes (TONT), p-Al doped TONT/n-TONT with an additional overlayer of alumina, are constructed to achieve 99.57% photodegradation of the stable organic pollutant methylene blue(MB) within 180 minutes, a degradation rate 17 times higher than by pure TONTs. A2ti-2 inhibitor The anodization at three different temperatures 20C, 280C and 400C followed by impregnation of Al is used for their preparation. The analyses of structure, chemical composition and morphology respectively by X-ray diffraction, X-ray photoelectron spectroscopy (XPS), high resolution transmission microscopy, Rutherford back scattering and field emission scanning electron microscopy confirm the formation of the hybrid structure.This structure exhibits the highest photodegradation rate with TONT based catalysts till date for MB blue, by enhancing the electron -hole separation, the absorption of visible photons and the adsorption sites for the pollutant. The optical data coupled with valence band XPS is used for elucidating the energy band structure of the p-n junctions and to gain insight into the effect of junction mechanism on photoactivity. The rectification ratios of the impregnated p-n junctions, determined by current -voltage measurements, are found to vary from 102 to 106. © 2020 IOP Publishing Ltd.Despite increasing interest in tin disulfide (SnS2) as a two-dimensional (2D) material due to its promising electrical and optical properties, the surface treatment of silicon dioxide (SiO2) substrates prior to the atomic layer deposition (ALD) deposition of SnS2 has not been thoroughly studied. In this paper, we prepared two types of SiO2 substrates with and without using an O2 plasma surface treatment and compared the ALD growth behavior of SnS2 on the SiO2 substrates. The hydrophilic properties of the two SiO2 substrates were investigated by X-ray photoelectron spectroscopy and contact angle measurements, which showed that using an O2 plasma surface treatment tuned the surface to be more hydrophilic. ALD-grown SnS2 thin films on the two different SiO2 substrates were characterized by X-ray diffraction, Raman spectroscopy, atomic force microscopy, and X-ray photoelectron spectroscopy. To estimate the exact thickness of the ALD-grown SnS2 thin films, transmission electron microscopy was used. Our data revealed that using O2 plasma surface treatment increased the growth rate of the initial ALD stage. Thus, the ALD-grown SnS2 thin film on the SiO2 substrate treated with O2 plasma was thicker than the film grown on the non-treated SiO2 substrate. © 2020 IOP Publishing Ltd.A close relationship between age and gut microbiota exists in invertebrates and vertebrates, including humans. Long-living people are a model for studying healthy aging; they also have a distinctive microbiota structure. The relationship between the microbiota of long-living people and aging phenotype remains largely unknown. Herein, the feces of long-living people were transplanted into mice, which were then examined for aging-related indices and beneficial bacteria. Mice transplanted with fecal matter from long-living people (L group) had greater α diversity, more probiotic genera (Lactobacillus and Bifidobacterium), and short-chain fatty acid producing genera (Roseburia, Faecalibacterium, Ruminococcus, Coprococcus) than the control group. L group mice also accumulated less lipofuscin and β-galactosidase and had longer intestinal villi. This study indicates the effects that the gut microbiota from long-living people have on healthy aging.Circulating growth hormone (GH) concentrations increase during pregnancy in mice and remain pituitary-derived. Whether abundance or activation of the GH secretagogue, ghrelin increase during pregnancy or in response to dietary octanoic acid supplementation are unclear. We therefore measured circulating GH profiles in late pregnant C57BL/6J mice and in aged-matched non-pregnant females, fed standard laboratory chow supplemented with 5% octanoic or palmitic (control) acid (n=4-13/group). Serum total and acyl-ghrelin concentrations, stomach and placenta ghrelin mRNA and protein expression, Pcsk1 (encoding prohormone convertase 1/3) and Mboat4 (membrane bound O-acyl transferase 4) mRNA were determined at zeitgeber (ZT) 13 and ZT23. Total and basal GH secretion were higher in late pregnant than non-pregnant mice (P less then 0.001), regardless of diet. At ZT13, serum concentrations of total (P=0.004), but not acyl-ghrelin, and the density of ghrelin-positive cells in the gastric antrum (P=0.019) were higher, and gastric Mboat4 and Pcsk1 mRNA expression were lower in pregnant than non-pregnant mice at ZT23. In the placenta, ghrelin protein was localised mostly to labyrinthine trophoblast cells. Serum acyl-, but not total, ghrelin was lower at mid-pregnancy than in non-pregnant mice, but not different at early or late pregnancy. In conclusion, dietary supplementation with 5% octanoic acid did not increase activation of ghrelin in female mice. Our results further suggest that increases in maternal GH secretion throughout murine pregnancy are not due to circulating acyl-ghrelin acting at the pituitary. Nevertheless, time-dependent increased circulating total ghrelin could potentially increase ghrelin action in tissues that express the acylating enzyme and receptor.
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