Notes

Vaccine-induced ErbB (EGFR/HER2)-specific immunity throughout quickly arranged dog cancer.
To investigate the overeruption of unopposed molars and the adaptation of alveolar bone height in young and adult rats.

A total of 56 4-week-old (young) and 26-week-old (adult) male Wistar rats were followed up longitudinally. In each age group (n = 28), 16 rats were included in the experimental subgroup, in which all the maxillary right molars were extracted, and 12 rats were included in the control subgroup. All rats were scanned at regular intervals with in vivo microcomputed tomography for a 12-week period, and the eruption rate of the mandibular first molars and the surrounding bone were measured, with the reference point at the mandibular canal. The molar categories were unopposed right molars and overloaded left molars in the experimental group and control molars in the control group.

The young unopposed molars had the highest mean eruption rate (172 ± 67 μm/day). The overeruption was most marked during the first 3 weeks postextraction, thereafter gradually returning to a level comparable to contlars compared to control molars.
To investigate the effect of aging on the morphology of the interface between monolithic implant crowns and standardized titanium base abutments.

Four groups of hybrid abutment crowns differing in restorative material (lithium disilicate [LD] or polymer-infiltrated ceramic network [PICN]) and in fabrication procedure of the interfacial zone for luting to a titanium abutment (milled during CAD/ CAM procedure [M] or prefabricated [P]) were formed LDS-M, LDS-P, PICN-M, and PICN-P (n = 10 each). The morphology of the crown-abutment interface was examined before and after artificial aging using scanning electron microscopy. The total gap length per specimen was measured at both time points, and intergroup (Kruskal-Wallis [KW]) plus pairwise (Wilcoxon Mann-Whitney [WMW]) comparisons were performed (α = .05).

Before aging, statistically significant differences in gap length were identified among groups (KW P = .0369) for PICN-P > LDS-P (WMW P = .0496) and LDS-M > LDS-P (WMW P = .0060). The effect of agin material and the nature of the interface influenced the interfacial gap dimension.
To determine the influence of thermal and mechanical cycling on fracture load and fracture pattern of resin nanoceramic crowns and polymer-infiltrated ceramic-network (PICN) crowns, both fabricated with CAD/CAM technology.

A total of 90 premolar crowns bonded to titanium abutments were divided into three groups of 30 crowns each 30 resin nanoceramic crowns (LU); 30 PICN crowns (VE); and 30 metal-ceramic crowns (MC). The 30 specimens of each group were further divided into three subgroups of 10 each that underwent (1) no treatment, (2) thermocycling (2,000 cycles, 5°C to 55°C), and (3) thermocycling with subsequent mechanical cycling (120,000 cycles, 80 N, 2 Hz). The specimens were loaded to failure, and two-way ANOVA and chi-square test were used to determine differences in fracture resistance and pattern.

Mechanical and thermal cycling significantly influenced the critical load to failure of the three materials; however, no significant differences were observed between the thermocycled materials and the materials that were thermocycled with subsequent mechanical cycling. The MC specimens experienced significantly higher fracture loads than those of the LU and VE specimens, which showed no differences from each other in fracture resistance. The fracture patterns showed chipping in MC crowns and partial or complete fracture in LU and VE crowns. The fracture pattern depended on the material and was unrelated to the type of treatment it underwent.

All crowns showed adequate resistance to normal masticatory forces in the premolar area. The cyclic fatigue load negatively influenced all three materials.
All crowns showed adequate resistance to normal masticatory forces in the premolar area. The cyclic fatigue load negatively influenced all three materials.
To three-dimensionally evaluate the internal fit at the implant-abutment interface of abutments fabricated with different workflows using a combination of the silicone replica technique and microcomputed tomography (μCT).

Thirty abutments were fabricated to restore internal-connection implants and were divided into three groups according to fabrication method (1) full digital (abutment machined using CAD/CAM system); (2) Ti-Base (prefabricated standard Ti-Base abutments); and (3) UCLA (UCLA-type abutments) (n = 10/group). Linear and volume measurements were performed to assess the internal misfit using a silicone replica of the implant-abutment interface misfit area, which was three-dimensionally reconstructed after μCT. The internal discrepancies in three different regions of interest (Gap
, Gap
, and Gap
) were assessed. Data were statistically evaluated using ANOVA and Tukey test (P < .05).

Ti-Base and UCLA abutments presented significantly lower misfit volume (0.49 mm
, 95% CI ± 0.045 mm
anorkflow (CAD/CAM custom abutments).
To investigate the influence of different postpolymerization strategies and artificial aging periods on the Martens hardness parameters of 3D-printed resin materials indicated for temporary use.

Disks made of four 3D-printed resin materials (n = 30 each) were additively manufactured and postpolymerized with three different postpolymerization devices (n = 10 specimens of each material per device). Disks cut from a prefabricated milling material served as a control. The Martens parameters (ie, Martens hardness [HM] and indentation modulus [E
]) were measured initially and after 14- and 28-day storage periods in 37°C distilled water. Sodium Monensin in vivo The data were statistically analyzed using univariate analysis, Kolmogorov Smirnov test, and nonparametric tests, including Kruskal-Wallis, Mann-Whitney U, and Wilcoxon tests (α = .05).

The highest impact on the Martens parameters was exerted by material (HM η

= 0.957, E
η

= 0.967, P < .001), followed by postpolymerization device (HM η

= 0.557, E
η

= 0. parameters. Such materials might be an alternative to conventional materials for the milling procedure.
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