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Circular RNA circRHOT1 leads to pathogenesis of non-small mobile carcinoma of the lung by epigenetically boosting C-MYC appearance via signing up KAT5.
Laboratory based X-ray micro-CT is a non-destructive testing method that enables three dimensional visualization and analysis of the internal and external morphology of samples. Although a wide variety of commercial scanners exist, most of them are limited in the number of degrees of freedom to position the source and detector with respect to the object to be scanned. Hence, they are less suited for industrial X-ray imaging settings that require advanced scanning modes, such as laminography, conveyor belt scanning, or time-resolved imaging (4DCT). We introduce a new X-ray scanner FleXCT that consists of a total of ten motorized axes, which allow a wide range of non-standard XCT scans such as tiled and off-centre scans, laminography, helical tomography, conveyor belt, dynamic zooming, and X-ray phase contrast imaging. Additionally, a new software tool 'FlexRayTools' was created that enables reconstruction of non-standard XCT projection data of the FleXCT instrument using the ASTRA Toolbox, a highly efficient and open source set of tools for tomographic projection and reconstruction.Both photonic quantum computation and the establishment of a quantum internet require fiber-based measurement and feed-forward in order to be compatible with existing infrastructure. Here we present a fiber-compatible scheme for measurement and feed-forward, whose performance is benchmarked by carrying out remote preparation of single-photon polarization states at telecom-wavelengths. The result of a projective measurement on one photon deterministically controls the path a second photon takes with ultrafast optical switches. By placing well-calibrated bulk passive polarization optics in the paths, we achieve a measurement and feed-forward fidelity of (99.0 ± 1)%, after correcting for other experimental errors. Our methods are useful for photonic quantum experiments including computing, communication, and teleportation.The temporal response of single-photon detectors is usually obtained by measuring their impulse response to short-pulsed laser sources. Itacnosertib In this work, we present an alternative approach using time-correlated photon pairs generated in spontaneous parametric down-conversion (SPDC). By measuring the cross-correlation between the detection times recorded with an unknown and a reference photodetector, the temporal response function of the unknown detector can be extracted. Changing the critical phase-matching conditions of the SPDC process provides a wavelength-tunable source of photon pairs. We demonstrate a continuous wavelength-tunability from 526 nm to 661 nm for one photon of the pair, and 1050 nm to 1760 nm for the other photon. The source allows, in principle, to access an even wider wavelength range by simply changing the pump laser of the SPDC-based source. As an initial demonstration, we characterize single-photon avalance detectors sensitive to the two distinct wavelength bands, one based on Silicon, the other based on Indium Gallium Arsenide.For low-order adaptive optics systems, a method that is able to correct for system aberrations in the final focal plane is presented. The paper presents a novel figure of merit, corresponding to the integrated non-normalized tip-tilt-free optical transfer function. The inherent singular value decomposition modal content of the interaction matrix is used to optimize this figure of merit. The method has proven to be stable and robust, providing a simple mean to facilitate diffraction limited imaging in an experimental setup for ophthalmic applications.Optical imaging of objects embedded within scattering media such as biological tissues suffers from the loss of resolving power. In our previous work, we proposed an approach called collective accumulation of single scattering (CASS) microscopy that attenuates this detrimental effect of multiple light scattering by combining the time-gated detection and spatial input-output correlation. In the present work, we perform a rigorous theoretical analysis on the effect of multiple light scattering to the optical transfer function of CASS microscopy. In particular, the spatial frequency-dependent signal to noise ratio (SNR) is derived depending on the intensity ratio of the single- and multiple-scattered waves. This allows us to determine the depth-dependent resolving power. We conducted experiments using a Siemens star-like target having various spatial frequency components and supported the theoretical derived SNR spectra. Our study provides a theoretical framework for understanding the effect of multiple light scattering in high-resolution and deep-tissue optical imaging.Speckle pattern analysis has been found by many researchers to be applicable to remote sensing of various biomedical parameters. This paper shows how analysis of dynamic differential speckle patterns scattered from subjects' sclera illuminated by a laser beam allows extraction of micro-saccades movement in the human eye. Analysis of micro-saccades movement using advanced machine learning techniques based on convolutional neural networks offers a novel approach for non-contact assessment of human blood oxygen saturation level (SpO2). Early stages of hypoxia can rapidly progress into pneumonia and death, and lives can be saved by advance remote detection of reduced blood oxygen saturation.We present a novel broadband continuously tunable microwave photonic delay line consisting of a modulator, a four-stage microring resonator delay line, a tunable optical bandpass filter, and a photodetector. Unlike the traditional microring delay lines working at the on-resonant wavelength, the microring resonators in our chip work at the anti-resonant wavelengths, leading to a large delay bandwidth and a small delay ripple. The experimental results show that relative group delay can be continuously tuned from 0 to 160 ps for microwave frequencies in the range of 0 to 16 GHz. The delay ripple is less than 6.2 ps. These results represent an important step towards the realization of integrated continuously tunable delay lines demanded in broadband microwave phased array antennas.Understanding the impact of the cladding tube structure on the overall guiding performance is crucial for designing a single-mode, wide-band, and ultra low-loss nested hollow-core anti-resonant fiber (HC-ARF). Here we thoroughly investigate on how the propagation loss is affected by the nested elements when their geometry is realistic (i.e., non-ideal). Interestingly, it was found that the size, rather than the shape, of the nested elements has a dominant role in the final loss performance of the regular nested HC-ARFs. We identify a unique 'V-shape' pattern for suppression of higher-order modes loss by optimizing free design parameters of the HC-ARF. We find that a 5-tube nested HC-ARF has wider transmission window and better single-mode operation than a 6-tube HC-ARF. We show that the propagation loss can be significantly improved by using anisotropic nested anti-resonant tubes elongated in the radial direction. Our simulations indicate that with this novel fiber design, a propagation loss as low as 0.11 dB/km at 1.
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