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Specialized medical along with genetic characterization involving adult-onset leukoencephalopathy brought on by CSF1R strains.
TNF-α significantly increased in G2, but decreased in all other groups. Creatinine increased significantly in groups G5, 6, 7, 8, 9, 11 and 12. In the kidneys of the diabetic rats, thickened capillary basement membrane, diffuse mesangial sclerosis and nodular glomerulosclerosis was observed. Rats treated with melatonin showed marked improvement in these symptoms. However, in those treated with vitamin D and E, thickened capillary basement membrane and mesangial sclerosis was still present.

Melatonin, administered either with or without insulin had a significant biochemical antioxidant effect and histological renoprotective effect. Conversely, vitamin D and E did not appear to have any effects on the parameters measured.
Melatonin, administered either with or without insulin had a significant biochemical antioxidant effect and histological renoprotective effect. Conversely, vitamin D and E did not appear to have any effects on the parameters measured.
The Medical Students' Stressor Questionnaire (MSSQ) is a specific tool to assess the degree of stress in medical students. However, this tool has not been validated in Sri Lanka. Therefore, this study contextually adapted the MSSQ and investigated its validity in the local context.

A total of 603 medical students, in various phases of their undergraduate training, from the Faculty of Medicine at the University of Colombo, participated in the study. Students who have completed their studies in the faculty for at least six months were included. The self-administered questionnaire was contextually adapted to the local setting and was approved by subject and language experts. Responses were analysed for construct validity (including exploratory factor analysis to estimate factor structure of the scale), sample adequacy, and internal consistency. Data were analysed using the SPSS statistical package.

The mean age of the study cohort was 23.3±SD 2.0 years, while 258 (42.8%) were males. The MSSQ scale significantly correlated with the General Health Questionnaire (
<0.001), indicating a strong concurrent validity. The exploratory factor analysis showed that items were loaded appropriately on five new factors, and the Kaiser-Meyer-Olkin measure (0.954) and Bartlett's test of sphericity (p<0.001) showed excellent sample adequacy. The internal consistency of the MSSQ overall (α=0.95), and each of the new factors (α > 0.82 for the first four factors and α=0.54 for the fifth) were satisfactory. The test-retest reliability was high (Pearson's r=0.918, p<0.001).

The contextually adapted MSSQ is a valid and reliable instrument that can be used in the assessment of stress among medical students.
The contextually adapted MSSQ is a valid and reliable instrument that can be used in the assessment of stress among medical students.
This study examines the extent of understanding of medical students from KSA and New Zealand (NZ) about predatory journals.

From March to July 2019, self-administered questionnaires were sent to fourth- and fifth-year students of two medical schools in KSA and NZ. Between-group comparisons were carried out using the two-sided Student's
test and the Chi-square test. Statistical significance was determined at a
-value <0.05.

A total of 263 students completed the questionnaire (response rate 59.1 percent KSA; 31 percent NZ). Prior research experience was significantly higher among KSA students (56.6 percent) as compared to NZ students (32.3 percent;
=0.0006). A significantly higher number of KSA students (75.6 percent) felt that they were under pressure to publish studies during their term at medical school as compared to only 12.3 percent of NZ medical students (
<0.0001). While one-third of the students in both countries were familiar with 'open-access publishing' (30.8 percent KSA versus 4to promote awareness about predatory journals are warranted.
This study aims to assess the psychosocial and clinical issues affecting physicians who have been directly involved in treating patients with novel coronavirus (COVID-19).

We recruited physicians from four hospitals in Jordan. A structured 20-item, self-administered survey was used to gather data. Descriptive statistics were employed to represent the numbers and percentages of the participants' responses to the survey items. Multivariate logistic regression was used to examine the relationship between the participants' traits and items related to the level of fear, the quality of care provided to patients, and social distancing among family members.

A total of 135 physicians participated; 65.9% were men. More than half reported moderate to high levels of fear (55.5%). The majority (71.1%) were moderately to highly concerned about becoming infected with COVID-19 from the patients they treated. Most physicians practiced adequate social distancing. While most of them thought that COVID-19 patients received a high quality of care, they generally perceived a shortage of specialised physicians and personal protective equipment (PPE). The ratings for the quality of care and social distancing practices were significantly associated with the presence or absence of training related to COVID-19.

The degree of fear and concerns about COVID-19's impact on physicians and their families was high. There were also concerns about the long-term consequences of COVID-19 on medical services.
The degree of fear and concerns about COVID-19's impact on physicians and their families was high. There were also concerns about the long-term consequences of COVID-19 on medical services.
Tobacco use poses a threat to the health of pregnant women and their children. Our study assessed the association between maternal exposure to secondhand smoke (SHS) during pregnancy and children's cerebral palsy (CP) in Shandong, China.

In our observational study, 5067 mother-child pairs were included from Shandong Province, China. Siremadlin nmr Mothers filled in questionnaires about exposure to SHS during pregnancy. Statistical analysis and logistic regression models were built in R program to estimate the association in adjusted odds ratio (AOR) between SHS exposure during pregnancy and risk of children's CP, after adjustment for potential confounders including delivery mode and baby's birthweight.

Exposure to SHS was noted among 3663 (72.3%) of the 5067 non-smoking mothers during their pregnancy. Of the 239 CP children within the study, 192 (80.3%) were exposed to SHS during pregnancy. Children born to mothers exposed to SHS during pregnancy had a higher risk of CP (AOR=1.44; 95% CI 1.02-2.04) than those born to non-exposed mothers, the risk increased by exposure time in the logistic regression model.
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