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508-0.974). However, somatic modulation or medical treatments targeting somatic modulation were not related to improvement.
Patients showing modulation after neck or jaw maneuvers have specific clinical characteristics. However, somatic modulation itself does not affect the final treatment outcome.
Patients showing modulation after neck or jaw maneuvers have specific clinical characteristics. However, somatic modulation itself does not affect the final treatment outcome.
This study aimed to assess if a short tinnitus treatment, combining counseling with broadband noise filtered by the hearing loss curves, provided significant relief in tinnitus patients.
25 tinnitus subjects of heterogeneous etiology were subjected to sound therapy, 1 hour per day, for 4 months. All of them underwent a unique initial counseling session aimed at undoing previous negative perceptions of tinnitus and highlighting the real expectations from tinnitus therapies. Customized stereo sound stimuli were designed by filtering broadband noise using the hearing loss curves of each ear. A monthly follow-up was carried out by assessing the severity of tinnitus through a validated Spanish version of the Tinnitus Handicap Inventory (THI).
88% (22 of 25) of the patients completing the treatment obtained significant relief after 4 months. After 4 months of treatment, the average decrease in THI from its initial value for the 22 successful participants was 29.
The average THI score reduction after 4 months of treatment can be considered to be an excellent improvement when compared with other similar studies. The proposed customized sound therapy was effective in reducing tinnitus in patients of heterogeneous etiology.
The average THI score reduction after 4 months of treatment can be considered to be an excellent improvement when compared with other similar studies. The proposed customized sound therapy was effective in reducing tinnitus in patients of heterogeneous etiology.
To investigate the efficacy of prompt concomitant corticosteroid treatment with single application of high-concentration intratympanic (IT) dexamethasone and tapered low-dose systemic methylprednisolone of an idiopathic sudden sensorineural hearing loss (ISSNHL).
Between September 2017 and September 2019, 86 adult patients met the criteria for the diagnosis of ISSNHL at baseline evaluation. The patients received immediate concomitant treatment with single high-concentration (24 mg/mL) IT dexamethasone and low-dose (48 mg) oral methylprednisolone for 1 week followed by tapered doses. Improvement in pure-tone average (PTA) and word recognition score (WRS) was determined after 1 and 6 months.
A total of 63 patients met the requirements for the analysis. PTA improved in 71% and WRS improved in 59% of patients with ISSNHL. PTA and WRS were statistically significantly different at different time points during the intervention (p<0.0005). Hearing improved in all measured frequencies from 125 to 8000 Hz until the second follow-up. In 65.4% of patients with tinnitus, the WRS has improved compared with 27.3% without tinnitus (p<0.05). In 69.2% of patients without vertigo, the WRS has improved compared with 41.7% with vertigo (p<0.05).
Prompt concomitant single high-concentration IT and low-dose systemic corticosteroid treatment is efficient in recovering hearing loss and speech discrimination in ISSNHL. Tinnitus positively predicts hearing outcome. Vertigo negatively predicts speech discrimination recovery.
Prompt concomitant single high-concentration IT and low-dose systemic corticosteroid treatment is efficient in recovering hearing loss and speech discrimination in ISSNHL. Tinnitus positively predicts hearing outcome. Vertigo negatively predicts speech discrimination recovery.
To examine the efficacy of an intratympanic steroid injection in tinnitus cases unresponsive to medical treatment.
The study was carried out at the Ear, Nose, and Throat Department with 107 patients (46 male, 61 female) between the ages of 20 and 77 with a mean of 42.8 years who had idiopathic tinnitus. Patients were randomized by simple randomization to receive intratympanic dexamethasone or isotonic solution. The patients received six intratympanic injections, two per week for three weeks. Tinnitus handicap index (THI) was performed before treatment and at first week, first month, and six months after the completion of the study protocol. The audiometric tests were performed six months after the treatment.
In the study group, pretreatment THI and post-treatment first month THI scores and pretreatment THI and post-treatment sixth month THI scores were significantly different whereas the same scores were not significantly different in the control group. The comparison of THI scores between the groups revealed significantly lower scores in the first and sixth months for the study group.
The effect of the intratympanic injection of dexamethasone on the efficacy of treatment of tinnitus severity was statistically significant.
The effect of the intratympanic injection of dexamethasone on the efficacy of treatment of tinnitus severity was statistically significant.
The purpose of this study was to analyze auditory brainstem response (ABR) waveforms of patients with tinnitus with normal hearing, according to tinnitus duration, and demonstrate the possible pathophysiological mechanisms of tinnitus.
From January 2016 to December 2017, patients who presented to our hospital with tinnitus as their chief complaint were enrolled and reviewed retrospectively. Pure tone audiometry and ABR tests were performed. The patients were classified into three groups according to tinnitus duration acute (<1 month), subacute (1-6 months), and chronic (>6 months). Selleck Mivebresib The amplitudes of waves I and V and the latencies of waves I, III, and V were evaluated. In this study, 177 ears of 128 patients with tinnitus with normal hearing were evaluated.
Wave V amplitude was significantly lower during the subacute phase than during the acute phase. The absolute latency value of wave V was greater during the subacute phase than during the acute phase. The interpeak latency I-V was significantly prolonged during the subacute phase compared with the acute and chronic phases.
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