Notes

A quinary covering move metal oxide involving NaNi1/4Co1/4Fe1/4Mn1/8Ti1/8O2 as a high-rate-capability and also long-cycle-life cathode substance pertaining to rechargeable salt electric batteries.
The practice of phubbing has become an emerging phenomenon of worldwide interest to researchers. The cause is due to the fact that smartphones are ubiquitous and are often used in co-present interactions. This behavior is generally considered inappropriate and is called "phubbing". Phubbing, as described by Chotpitayasunondh and Douglas (2018), is the act of snubbing someone in a social setting by looking at one's phone instead of paying attention to the other person. The aim of this article is to provide an overview of research studies on phubbing through a review of the current literature. find more To do this, a search was carried out in an international database, finding 84 relevant articles in English that appeared in peer-reviewed journals published between 2012, the year in which the term 'phubbing' appears, and January 2020. The review covers the main fields of research studies on phubbing behaviors. Likewise, the results of the study show the distribution of published articles on phubbing by year that detail the type of study and the methodological approach and, finally, the research journals that have published articles on phubbing. The results of this review are expected to stimulate and guide future research in this field.Although total hip arthroplasty (THA) is considered to be the most successful orthopedic operation in restoring mobility and relieving pain, common Metal-on-Metal (MoM) implants developed in the past decade suffer from severe inflammatory reactions of the surrounding tissue caused by the premature corrosion and degradation of the implant. A substantial amount of research has been dedicated to the investigation of mechanically driven fretting and crevice corrosion as the primary mechanism of implant failure. However, the exact mechanism by which hip implant breakdown occurs remains unknown, as current in vitro fretting and crevice corrosion studies have failed to completely replicate the corrosion characteristics of recovered implants. Here, we show that minor electric potential oscillations on a model hip implant replicate the corrosion of failed implants without the introduction of mechanical wear. We found in a controlled lab setting that small electrical oscillations, of similar frequency and magnitude as those resulting from ambient electromagnetic waves interacting with the metal of the implant, can force electrochemical reactions within a simulated synovial fluid environment that have not been previously predicted. In lab testing we have shown the replication of titanium, phosphorous, and oxygen deposition onto the surface of ASTM astmF75 CoCrMo metal alloy test specimens, matching the chemical composition of previously retrieved wear particles from failed patient prosthetics. Our results demonstrate that the electrical activity and ensuing electrochemical activity excites two corrosion failure modes direct dissolution of the medically implantable alloy, leaching metal ions into the body, and surface deposition growth, forming the precursor of secondary wear particles. We anticipate our findings to be the foundation for the future development and testing of electrochemically resistant implantable material.Arenaviral infections often result lethal hemorrhagic fevers, affecting primarily in African and South American regions. To date, there is no FDA-approved licensed vaccine against arenaviruses and treatments have been limited to supportive therapy. Hence, the study was employed to design a highly immunogenic cross-reactive vaccine against Arenaviridae family using reverse vaccinology approach. The whole proteome of Lassa virus (LASV), Lymphocytic Choriomeningitis virus (LCMV), Lujo virus and Guanarito virus were retrieved and assessed to determine the most antigenic viral proteins. Both T-cell and B-cell epitopes were predicted and screened based on transmembrane topology, antigenicity, allergenicity, toxicity and molecular docking analysis. The final constructs were designed using different adjuvants, top epitopes, PADRE sequence and respective linkers and were assessed for the efficacy, safety, stability and molecular cloning purposes. The proposed epitopes were highly conserved (84%-100%) and showed greater cumulative population coverage. Moreover, T cell epitope GWPYIGSRS was conserved in Junin virus (Argentine mammarenavirus) and Sabia virus (Brazilian mammarenavirus), while B cell epitope NLLYKICLSG was conserved in Machupo virus (Bolivian mammarenavirus) and Sabia virus, indicating the possibility of final vaccine construct to confer a broad range immunity in the host. Docking analysis of the refined vaccine with different MHC molecules and human immune receptors were biologically significant. The vaccine-receptor (V1-TLR3) complex showed minimal deformability at molecular level and was compatible for cloning into pET28a(+) vector of E. coli strain K12. The study could be helpful in developing vaccine to combat arenaviral infections in the future. However, further in vitro and in vivo trials using model animals are highly recommended for the experimental validation of our findings.There are a myriad of bottleneck variables that constrict the overall manufacturing capacity and make improvement decisions complex. Consequently, this study aims to identify and analyse the copious variables to pinpoint the key variable factors that influence and turn the manufacturing elements into bottleneck problem to prioritize process improvement effort. The study is limited to identifying and analysing the numerous bottleneck variables to gain insight into how much each of the variables influences the process output via the manufacturing elements. The 76-bottleneck variables abstracted from the literature were used to craft a structured questionnaire that were administered to respondents in the manufacturing industry whose size was determined at a 95% confidence level and 5% error margin respectively. The 95% confidence level is chosen to ensure adequate representation of the population and to validate the data for the study. The respondents' scores were collated into (m x n) data matrix which served ad in this study are generic and the improvement effort should focus on addressing the principal variables while not neglecting the middling and weakling variables.
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