Notes

Long lasting Dipole Moments Increase Digital Combining along with Singlet Fission in Pentacene.
Six breeding lines selected from the south and eight breeding lines selected from the north were tested and compared to two common check clones at five locations in Ghana. A Finlay-Wilkinson stability analysis resulted in stable performances within the target mega-environment from which the genotypes were selected, but predominantly without adaptation to the other region. Our results provide a strong rationale for running separate programs to allow for faster genetic progress in each of these two major West African mega-environments by selecting for specific and broad adaptation. © 2019 The Authors. Crop Science published by Wiley Periodicals, Inc. on behalf of Crop Science Society of America.The ascent of hydrous magma prior to volcanic eruptions is largely driven by the formation of H2O vesicles and their subsequent growth upon further decompression. Porosity controls buoyancy as well as vesicle coalescence and percolation, and is important when identifying the differences between equilibrium or disequilibrium degassing from textural analysis of eruptive products. Decompression experiments are routinely used to simulate magma ascent. Samples exposed to high temperature (T) and pressure (P) are decompressed and rapidly cooled to ambient T for analysis. During cooling, fluid vesicles may shrink due to decrease of the molar volume of H2O and by resorption of H2O back into the melt driven by solubility increase with decreasing T at P  less then  300 MPa. Here, we quantify the extent to which vesicles shrink during cooling, using a series of decompression experiments with hydrous phonolitic melt (5.3-3.3 wt% H2O, T between 1323 and 1373 K, decompressed from 200 to 110-20 MPa). Most samples degassed at near-equilibrium conditions during decompression. However, the porosities of quenched samples are significantly lower than expected equilibrium porosities prior to cooling. At a cooling rate of 44 K·s-1, the fictive temperature T f, where vesicle shrinkage stops, is up to 200 K above the glass transition temperature (T g), Furthermore, decreasing cooling rate enhances vesicles shrinkage. We assess the implications of these findings on previous experimental degassing studies using phonolitic melt, and highlight the importance of correctly interpreting experimental porosity data, before any comparison to natural volcanic ejecta can be attempted. © The Author(s) 2020.Observations from the Kepler mission have revealed frequent superflares on young and active solar-like stars. Superflares result from the large-scale restructuring of stellar magnetic fields, and are associated with the eruption of coronal material (a coronal mass ejection, or CME) and energy release that can be orders of magnitude greater than those observed in the largest solar flares. These catastrophic events, if frequent, can significantly impact the potential habitability of terrestrial exoplanets through atmospheric erosion or intense radiation exposure at the surface. MK-8617 We present results from numerical modeling designed to understand how an eruptive superflare from a young solar-type star, κ 1 Cet, could occur and would impact its astrospheric environment. Our data-inspired, three-dimensional magnetohydrodynamic modeling shows that global-scale shear concentrated near the radial-field polarity inversion line can energize the closed-field stellar corona sufficiently to power a global, eruptive superflare that releases approximately the same energy as the extreme 1859 Carrington event from the Sun. We examine proxy measures of synthetic emission during the flare and estimate the observational signatures of our CME-driven shock, both of which could have extreme space-weather impacts on the habitability of any Earth-like exoplanets. We also speculate that the observed 1986 Robinson-Bopp superflare from κ 1 Cet was perhaps as extreme for that star as the Carrington flare was for the Sun.[This corrects the article DOI 10.1371/journal.pone.0050093.].Evidence suggests the existence of association between a large panel of modifiable biomarkers representing inflammation, coagulation, paraoxonase, and endothelial activation pathways and carotid atherosclerosis. Thus, this study investigated whether CRP, FGA, FGB, FGG, PON1, and EDNRA gene variants affected plasma hs-CRP, fibrinogen levels, and thickness of carotid intima media thickness (IMT). Nineteen single-nucleotide polymorphisms of CRP, FGA, FGB, FGG, PON1, and EDNRA genes were examined in 480 participants from 160 families. Carotid IMT was measured by ultrasound. Generalized linear models with generalized estimating equation were utilized to consider the dependence of subjects within families. In the recessive model, homozygotes for the minor alleles of rs1800789, rs1800790 and rs4220 SNPs in FGB gene indicated a reduced risk of IMT (Exp. β = 0.89, 0.89, 0.88), which remained significant after adjustment for confounding factors. Significant interaction effects between CRP SNP rs1130864 and rs3093059 and gender for IMT were observed with a significant association in men only. Men carrying minor-minor genotype of CRP SNP rs1130864 and rs3093059 had 0.70- and 0.78-fold lower IMT than men carrying minor-major/major-major genotype. We also observed that the interaction of CRP SNP rs1130864 and rs3093059 with obesity on IMT, hs-CRP and fibrinogen levels. These results support the hypothesis that inflammatory genes are involved in atherosclerosis, most likely via complex gene-gender and gene-obesity interactions.BACKGROUND Transfusion-associated graft-versus-host disease (TA-GvHD) is caused by leukocytes, specifically T cells within a transfused blood product. Currently, the prevention of transfusion-associated graft-versus-host disease is performed by irradiation of blood products. With a sufficient reduction of leukocytes, the risk for TA-GvHD can be decreased. With consistent advances in current state-of-the-art blood filters, we herein propose that double filtration can sufficiently reduce leukocytes to reduce the risk for TA-GvHD. MATERIALS Thirty RBC concentrates were filtered with leukocyte filters, followed by storage at 1-6 oC for 72 hours, and then a second filtration was performed. Residual leukocytes in the double-filtered RBC units (n = 30) were assessed with flow cytometric methods, and an additional assay with isolated peripheral blood mononuclear cells (PBMCs) (n = 6) was done by both flow cytometric methods and an automated hematology analyzer. Quality of the RBCs after filtration was evaluated by hematological and biochemical tests.
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