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9% with CCRT vs. 87.4% without CCRT, p = 0.006) in those with more than one risk factor. Postoperative CCRT did not affect the 5-year LRFS (100% with CCRT vs. 99.0% without CCRT, p = 0.66) in patients with no risk factors.
Postoperative CCRT significantly decreased LR in patients with pT3N0 rectal cancer with a negative resection margin but having a distance from the anal verge ≤ 5 cm or DRM ≤ 2 cm.
Postoperative CCRT significantly decreased LR in patients with pT3N0 rectal cancer with a negative resection margin but having a distance from the anal verge ≤ 5 cm or DRM ≤ 2 cm.
Long-acting reversible contraception is highly effective in preventing unintended pregnancy and unsafe abortion. An educational video administered during early postpartum period might be an effective tool to improve postpartum LARC use. The objectives were to evaluate whether a postpartum educational video about LARC could increase postpartum LARC utilization at 6-8weeks postpartum and to assess why postpartum women did not receive LARC.
This randomized-controlled trial was conducted at the postpartum unit of a university Hospital between August 2016 and February 2017. Postpartum women who were aged > 20years and willing to participate were recruited. Participants allocated to the study group watched the 7-min educational video on LARC methods while the control group did not. To assess LARC utilization, data were collected at 6-8weeks postpartum using telephone calls and/or medical record review to determine postpartum contraception use and reasons for not using LARC.
Two-hundred and seventy participants were enrolled, and the video (135) and non-video (135) groups had similar baseline characteristics. In the video group, 57.8% (95% CI 49.0-66.2) reported using a LARC method, compared to 25.9% (95% CI 18.8-34.2) in the non-video group (p < 0.05). The reasons for not using LARC in both groups were inconvenience of access (42.0-43.8%) and uncertainty about methods (17.0-24.6%).
The educational video introduced at immediate postpartum period was efficacious in increasing the utilization of LARC at 6-8weeks postpartum. Inconvenience of access was the most common reason cited for not using LARC.
Clinicaltrials.in.th TCTR20171225001 "retrospectively registered".
Clinicaltrials.in.th TCTR20171225001 "retrospectively registered".
Modern strategies for the screening and diagnosis of Gestational Diabetes Mellitus (GDM) rely on universal Oral Glucose Tolerance Test (OGTT). However, they are unsustainable in low-income countries. In this study, we aimed at assessing the feasibility of a simplified diagnostic policy.
The study took place in an urban referral hospital in Freetown, Sierra Leone. During an 11-month period, pregnant women were offered capillary blood test for glucose assessment. They could be screened at any time during pregnancy. GDM was diagnosed if fasting glucose was ≥ 92mg/dl or if the OGTT was positive. The latter was prescribed only to women presenting after 24weeks' gestation with at least one risk factor for GDM and fasting capillary glucose between 85 and 91mg/dl. A definitive diagnosis required confirmation to this aim, women with values above the thresholds were invited to refer the next working day for repeating the test after fasting overnight.
Overall, 7827 women were referred for screening, of whom 6872 (87%) underwent at least one capillary glucose assessment. However, 895 of those who had a positive test did not return for confirmation. Overall, a definite assessment could be done in 5799 subjects corresponding to 76% (95% CI 75-77%) of those eligible. GDM was diagnosed in 128 women (1.9%, 95% CI 1.6-2.2%). Based on an expected confirmation rate of 22% (calculated from those who referred for confirmation) in the 895 women who did not come back, one could infer that GDM would have been diagnosed in additional 197 women, raising the prevalence to 4.7% (95% CI 4.2-5.3%).
Three quarters of subjects could be assessed with our approach. Data also suggest that GDM is not rare even if identification of affected cases remains challenging.
Three quarters of subjects could be assessed with our approach. Data also suggest that GDM is not rare even if identification of affected cases remains challenging.The purpose of the main research was to investigate the effects of methyl jasmonate (MeJA) (0.05, 0.25, 0.5, and 2.5 mM) on the pollen germination and tube elongation of Pinus nigra. Total pollen germination rate increased after MeJA treatments while the most enhancement was observed at 0.05-mM MeJA. No germination was observed at 2.5-mM MeJA. Although the unipolar and bipolar germination were observed in all groups, no significant changes were observed in unipolar and bipolar pollen germination rates after MeJA treatments. Tube length increased only at 0.05-mM MeJA. Although branched tubes were observed in all groups, branched tube rate increased only at 0.05-mM MeJA. Although two branched, three branched, and consecutive branched tubes were observed in all groups, the most common branching type was two branched type in all groups. Although anisotropy of actin filaments in the shank and apex of unbranched tubes decreased after MeJA treatments, the most decrease was observed at 0.05-mM MeJA. Also, anisotropy of actin filaments in the shank and in pre-branching region of branched tubes decreased only at 0.25-mM MeJA. Anisotropy of both two apexes of a branched tube changed only at 0.25- and 0.5-mM MeJA. Callose accumulation in the apex of unbranched and branched tubes increased in parallel with the increase in MeJA concentration. However, more callose is accumulated in one apex than the other apex of a branched tube. In conclusion, MeJA affected the actin organization, changed the callose distribution, and altered the pollen tube growth of Pinus nigra.For Fig. 4, an internal working draft of the image depicting the device placed in the heart was erroneously provided during the production process. The original article has been updated to include the correct version.
PR interval prolongation > 200ms resulting in the diagnosis of first-degree atrioventricular block (AVB1) is caused by a delay in the AV nodal/His conduction and/or the right intra-atrial conduction (RIAC). The aim of the study was to assess the prevalence of AVB1 due to RIAC delay (AVB1 with normal AH and HV) in patients with atrial fibrillation (AF) and atrial flutter (AFlu).
We included 1067 consecutive patients (33% female, age 63 ± 13years) referred for catheter ablation of AF (AF-group) (453 patients), AF and AFlu (136 patients), AFlu (292 patients), and AVNRT/AVRT (186 patients). SB-3CT manufacturer AH-, HV-, PR-interval, and P-wave duration were measured on the 12-lead ECG and the intracardiac electrograms in sinus rhythm. RIAC delay was defined as a prolonged PR interval > 200ms with normal AH and HV intervals.
The prevalence of AVB1 is higher in patients with AFlu (41%) and AF (21%) and patients with both arrhythmias (30%) as compared with a reference group (8%) of patients with AVNRT/AVRT. AVB1 was due to RIAC delay in 42 of 67 patients (63%) in the AF-group, in 37 of 96 patients (39%) in the AFlu-group, and in 17 of 36 patients (47%) in the AF/AFlu group, respectively.
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